|
.0 |
.003 |
.026 |
.017 |
.567 |
.002 |
.001 |
.021 |
.0 |
.008 |
.012 |
.001 |
.008 |
.0 |
.065 |
.019 |
.043 |
.101 |
.001 |
.077 |
.001 |
.0 |
.002 |
.024 |
.0 |
.005 |
.003 |
.0 |
.005 |
.0 |
.001 |
.003 |
.002 |
.002 |
.035 |
.011 |
.003 |
.042 |
.015 |
.002 |
.012 |
.013 |
.004 |
.002 |
.693 |
.858 |
.081 |
.125 |
.262 |
.397 |
.169 |
.001 |
.036 |
.0 |
.025 |
.012 |
.0 |
.0 |
.001 |
.005 |
.002 |
.044 |
.005 |
.0 |
.0 |
.072 |
.375 |
.273 |
.153 |
.041 |
.0 |
.0 |
.012 |
.0 |
.0 |
.0 |
.0 |
.001 |
.0 |
.001 |
.0 |
.001 |
.001 |
.001 |
.001 |
.0 |
.012 |
.001 |
.003 |
.002 |
.004 |
.706 |
.843 |
.003 |
.035 |
.045 |
.548 |
.028 |
.428 |
.134 |
.001 |
.135 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
.001 |
.001 |
.0 |
.0 |
.0 |
.0 |
.0 |
.0 |
.0 |
.064 |
.041 |
.089 |
.256 |
.002 |
.022 |
.03 |
.0 |
.001 |
.001 |
.0 |
.0 |
.003 |
.001 |
.017 |
.015 |
.152 |
.005 |
.023 |
.001 |
.001 |
.0 |
.015 |
.006 |
.005 |
.001 |
.006 |
.002 |
.054 |
.002 |
.007 |
.001 |
.012 |
.761 |
.945 |
.032 |
.675 |
.956 |
.719 |
1.0 |
1.0 |
.68 |
.259 |
.837 |
.579 |
.984 |
.542 |
.005 |
.999 |
.276 |
.0 |
.007 |
.007 |
.001 |
.199 |
.001 |
.684 |
.007 |
.135 |
.003 |
.008 |
.002 |
.0 |
.002 |
.007 |
.015 |
.176 |
.088 |
.055 |
.017 |
-- |
.035 |
.027 |
.015 |
.047 |
.01 |
.121 |
.031 |
.028 |
.048 |
.069 |
.007 |
.008 |
.003 |
-- |
.03 |
.0 |
.116 |
.001 |
.011 |
.01 |
.018 |
.011 |
.08 |
.01 |
.008 |
.0 |
.0 |
.001 |
.971 |
.0 |
.0 |
.001 |
.001 |
.003 |
.001 |
.005 |
.0 |
.001 |
.084 |
.033 |
.006 |
.0 |
.005 |
.001 |
.002 |
.017 |
.004 |
.003 |
.0 |
.118 |
.0 |
.018 |
1.0 |
.0 |
.0 |
.009 |
.015 |
.0 |
.002 |
.014 |
.005 |
.008 |
.0 |
.033 |
.016 |
.002 |
.003 |
.05 |
.001 |
.011 |
.096 |
.009 |
.115 |
.039 |
.011 |
.018 |
.006 |
.054 |
.044 |
.031 |
.159 |
.279 |
.002 |
.179 |
.207 |
.004 |
.01 |
.184 |
.236 |
.037 |
.0 |
.004 |
.006 |
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
Cxcl11
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
Cxcl10
|
Cxcl10
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
|
Art3
|
Art3
|
Art3
|
Art3
|
Art3
|
Art3
|
Art3
|
Art3
|
Art3
|
Art3
|
Art3
|
Art3
|
Art3
|
Art3
|
Art3
|
Art3
|
Art3
|
Art3
|
Art3
|
Art3
|
Art3
|
Art3
|
Art3
|
Art3
|
Art3
|
Art3
|
Art3
|
Art3
|
Art3
|
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
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--
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|
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|
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|
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--
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--
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|
--
|
--
|
--
|
--
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--
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--
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--
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--
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--
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--
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--
|
--
|
--
|
--
|
--
|
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|
--
|
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|
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|
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|
--
|
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|
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|
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|
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--
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|
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|
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|
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--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
|
C |
G |
T |
G |
C |
T |
T |
A |
T |
C |
T |
T |
C |
A |
C |
T |
A |
G |
T |
C |
G |
C |
A |
T |
G |
T |
C |
C |
A |
A |
T |
G |
T |
T |
G |
C |
T |
A |
C |
C |
G |
A |
G |
A |
A |
C |
C |
T |
G |
G |
G |
G |
A |
A |
G |
T |
A |
G |
A |
T |
C |
G |
C |
T |
T |
G |
C |
G |
T |
A |
A |
G |
C |
T |
T |
T |
T |
C |
T |
T |
T |
C |
C |
T |
A |
T |
A |
T |
T |
T |
T |
C |
T |
A |
A |
T |
G |
G |
C |
T |
A |
C |
C |
T |
T |
A |
C |
T |
T |
G |
T |
C |
C |
T |
A |
T |
T |
A |
T |
T |
A |
C |
C |
A |
A |
C |
G |
A |
C |
A |
T |
C |
T |
A |
C |
A |
A |
T |
A |
T |
T |
A |
C |
A |
A |
A |
T |
C |
C |
A |
A |
A |
G |
T |
C |
C |
A |
T |
G |
T |
C |
G |
T |
G |
G |
C |
A |
C |
G |
G |
C |
C |
T |
T |
C |
T |
A |
T |
A |
T |
A |
A |
C |
A |
A |
C |
T |
A |
C |
C |
A |
G |
C |
C |
G |
G |
C |
C |
A |
C |
T |
C |
A |
C |
G |
A |
G |
G |
A |
A |
A |
A |
C |
A |
T |
A |
A |
G |
T |
G |
C |
C |
G |
C |
A |
A |
T |
G |
T |
A |
C |
C |
T |
C |
C |
A |
A |
G |
T |
G |
A |
C |
C |
T |
G |
G |
C |
A |
C |
G |
A |
A |
G |
G |
A |
G |
A |
C |
G |
C |
G |
G |
G |
G |
A |
G |
T |
T |
A |
A |
G |
A |
G |
A |
C |
C |
T |
C |
C |
C |
T |
G |
T |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
A
|
A
|
C
|
T
|
T
|
C
|
C
|
G
|
C
|
T
|
C
|
C
|
T
|
G
|
G
|
T/C
|
C
|
A
|
C
|
C/T
|
A
|
T
|
G
|
C
|
A
|
C
|
G
|
T
|
T
|
G
|
C
|
A
|
C
|
C
|
A
|
T
|
C
|
T
|
T
|
T
|
A
|
G
|
C
|
G
|
T
|
T
|
G
|
C
|
A
|
A
|
T
|
C
|
G
|
G
|
T
|
A
|
C
|
A
|
A/G
|
C
|
T
|
A
|
T
|
C
|
C
|
A
|
T
|
A
|
G
|
G
|
G
|
A
|
T
|
T/C
|
C
|
C
|
C
|
T
|
C
|
C
|
A
|
T
|
T
|
A
|
G
|
C
|
G
|
C
|
C
|
C
|
A
|
T
|
G
|
G
|
G
|
C
|
A
|
A
|
T
|
G
|
A/G
|
T
|
T
|
A
|
G
|
G
|
G
|
C
|
C
|
A
|
A
|
T
|
T
|
C
|
G
|
C
|
G
|
T
|
G
|
G
|
C
|
G
|
T
|
G
|
G
|
G
|
A
|
T
|
T
|
T
|
C
|
T
|
C
|
G
|
A
|
G
|
G
|
C
|
G
|
C
|
C
|
G
|
T
|
A/G
|
G
|
A/G
|
A
|
G
|
T
|
G
|
G
|
G
|
A
|
G
|
G
|
T
|
G
|
C
|
A
|
A
|
T
|
C
|
C
|
A
|
A
|
T
|
G
|
T
|
A
|
A
|
T
|
T
|
C
|
C
|
T
|
G
|
G
|
A
|
G
|
G
|
G
|
G
|
T
|
G
|
C
|
T
|
C
|
G
|
G
|
A
|
G
|
T
|
T
|
T
|
A
|
G/A
|
T
|
T
|
G
|
G
|
C
|
T
|
T
|
T
|
A
|
G
|
A
|
A
|
G
|
G
|
G
|
G
|
T
|
T
|
C
|
G
|
G
|
T
|
G
|
A
|
T
|
C/G
|
T
|
T
|
T
|
G
|
C
|
A
|
T/A
|
G
|
T
|
T
|
C
|
T
|
T
|
G
|
G
|
A
|
C
|
C
|
A/T
|
T
|
T
|
A
|
C
|
G/A
|
T
|
T
|
A
|
C
|
T
|
G
|
A
|
T
|
T
|
A
|
C
|
T
|
A
|
T
|
A
|
T
|
A
|
A
|
G
|
A
|
C
|
C
|
G
|
G
|
C
|
G
|
A
|
A/C
|
C/A
|
T
|
C
|
T
|
T
|
T
|
C
|
A
|
T/G
|
|