Rgma (repulsive guidance molecule BMP co-receptor a)

Gene: Rgma (repulsive guidance molecule BMP co-receptor a) Rattus norvegicus

Analyze

Symbol:

Rgma

Name:

repulsive guidance molecule BMP co-receptor a

RGD ID:

1311983

Description:

Predicted to enable coreceptor activity and transferrin receptor binding activity. Involved in negative regulation of axon regeneration; negative regulation of collateral sprouting; and positive regulation of neuron projection development. Predicted to be located in cell surface and endoplasmic reticulum. Predicted to be active in plasma membrane. Used to study middle cerebral artery infarction. Biomarker of middle cerebral artery infarction; sciatic neuropathy; and temporal lobe epilepsy. Human ortholog(s) of this gene implicated in multiple sclerosis. Orthologous to human RGMA (repulsive guidance molecule BMP co-receptor a); PARTICIPATES IN Bone morphogenetic proteins signaling pathway; INTERACTS WITH 1,2-dimethylhydrazine; 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

LOC308739; repulsive guidance molecule A; repulsive guidance molecule family member A; RGM domain family, member A

RGD Orthologs

Alliance Genes

More Info

more info ...

Candidate Gene For:

Eae30

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	136,538,782 - 136,582,763 (+)	NCBI		GRCr8
mRatBN7.2	1	127,128,934 - 127,172,918 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	127,128,934 - 127,172,918 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	135,121,700 - 135,165,733 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	142,291,803 - 142,335,840 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	135,115,277 - 135,159,262 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	134,699,053 - 134,742,512 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	134,699,299 - 134,742,514 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	135,725,212 - 135,768,409 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	128,547,399 - 128,591,304 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	1	128,641,975 - 128,668,760 (+)	NCBI
Celera	1	119,260,496 - 119,304,476 (+)	NCBI		Celera
Cytogenetic Map	1	q31	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

genetic disease (ISO)

middle cerebral artery infarction (IEP,IMP)

multiple sclerosis (ISO)

Penetrating Eye Injuries (IEP)

sciatic neuropathy (IEP)

Spinal Cord Injuries (IMP)

temporal lobe epilepsy (IEP)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (EXP,ISO)

1-naphthyl isothiocyanate (EXP)

17alpha-ethynylestradiol (ISO)

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,3,7,8-Tetrachlorodibenzofuran (EXP)

3,3',5,5'-tetrabromobisphenol A (ISO)

3-isobutyl-1-methyl-7H-xanthine (ISO)

6-propyl-2-thiouracil (EXP)

acrylamide (EXP,ISO)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

amitrole (EXP)

aristolochic acid A (ISO)

arsane (ISO)

arsenic atom (ISO)

atrazine (ISO)

benzo[a]pyrene (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

bromobenzene (EXP)

butanal (ISO)

cadmium atom (ISO)

cadmium dichloride (ISO)

cantharidin (ISO)

carbamazepine (ISO)

CGP 52608 (ISO)

chlorpyrifos (ISO)

cisplatin (ISO)

Cuprizon (EXP)

dexamethasone (ISO)

dorsomorphin (ISO)

doxorubicin (ISO)

endosulfan (EXP)

epoxiconazole (ISO)

ethanol (ISO)

folic acid (ISO)

fulvestrant (ISO)

gentamycin (EXP)

indometacin (ISO)

Licochalcone B (ISO)

mercury dibromide (ISO)

methimazole (EXP)

methoxychlor (EXP)

methylmercury chloride (ISO)

methylphenidate (ISO)

N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal (ISO)

niclosamide (ISO)

p-chloromercuribenzoic acid (ISO)

panobinostat (ISO)

paraquat (EXP)

PCB138 (EXP)

phenylmercury acetate (ISO)

propanal (ISO)

SB 431542 (ISO)

silicon dioxide (ISO)

silver atom (ISO)

silver(0) (ISO)

sodium arsenate (ISO)

tetrachloromethane (EXP,ISO)

thapsigargin (ISO)

trichloroethene (EXP)

trichostatin A (ISO)

triclosan (ISO)

trimellitic anhydride (ISO)

urethane (ISO)

valproic acid (ISO)

vorinostat (ISO)

zaragozic acid A (EXP,ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

BMP signaling pathway (IBA,ISO)

membrane protein ectodomain proteolysis (ISO)

negative regulation of axon regeneration (IMP)

negative regulation of collateral sprouting (IMP)

negative regulation of neuron projection development (IDA,ISO)

neural tube closure (ISO)

neuron projection development (ISO)

positive regulation of membrane protein ectodomain proteolysis (ISO)

positive regulation of neuron projection development (IDA)

positive regulation of transcription by RNA polymerase II (ISO)

regulation of BMP signaling pathway (ISO)

Cellular Component

cell surface (ISO)

endoplasmic reticulum (IEA,ISO)

plasma membrane (IBA)

side of membrane (IEA)

Molecular Function

coreceptor activity (IBA,ISO)

protein binding (ISO)

signaling receptor binding (ISO)

transferrin receptor binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

Bone morphogenetic proteins signaling pathway (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Induction of repulsive guidance molecule in neurons following sciatic nerve injury.	Doya H, etal., J Chem Neuroanat. 2006 Aug;32(1):74-7. Epub 2006 Jul 24.
2.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3.	RGMa inhibition promotes axonal growth and recovery after spinal cord injury.	Hata K, etal., J Cell Biol. 2006 Apr 10;173(1):47-58. Epub 2006 Apr 3.
4.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
5.	RGMA and IL21R show association with experimental inflammation and multiple sclerosis.	Nohra R, etal., Genes Immun. 2010 Jun;11(4):279-93. Epub 2010 Jan 14.
6.	TACE cleaves neogenin to desensitize cortical neurons to the repulsive guidance molecule.	Okamura Y, etal., Neurosci Res. 2011 Sep;71(1):63-70. doi: 10.1016/j.neures.2011.05.012. Epub 2011 May 27.
7.	PID Annotation Import Pipeline	Pipeline to import Pathway Interaction Database annotations from NCI into RGD
8.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
9.	Comprehensive gene review and curation	RGD comprehensive gene curation
10.	RGMA and neogenin protein expression are influenced by lens injury following optic nerve crush in the rat retina.	Schnichels S, etal., Graefes Arch Clin Exp Ophthalmol. 2012 Jan;250(1):39-50. doi: 10.1007/s00417-011-1791-9. Epub 2011 Sep 2.
11.	Repulsive guidance molecule a regulates hippocampal mossy fiber branching in vitro.	Shibata K, etal., Neuroreport. 2013 Aug 7;24(11):609-15. doi: 10.1097/WNR.0b013e3283632c08.
12.	Potential roles of the RGMa-FAK-Ras pathway in hippocampal mossy fiber sprouting in the pentylenetetrazole kindling model.	Song MY, etal., Mol Med Rep. 2015 Mar;11(3):1738-44. doi: 10.3892/mmr.2014.2993. Epub 2014 Nov 21.
13.	Peptides derived from repulsive guidance molecule act as antagonists.	Suda M, etal., Biochem Biophys Res Commun. 2008 Jul 4;371(3):501-4. doi: 10.1016/j.bbrc.2008.04.114. Epub 2008 Apr 29.
14.	CRMP-2 is involved in axon growth inhibition induced by RGMa in vitro and in vivo.	Wang T, etal., Mol Neurobiol. 2013 Jun;47(3):903-13. doi: 10.1007/s12035-012-8385-3. Epub 2012 Dec 30.
15.	Electrical stimulation of olfactory bulb downregulates RGMa expression after ischemia/reperfusion injury in rats.	Zhang G, etal., Brain Res Bull. 2011 Oct 10;86(3-4):254-61. doi: 10.1016/j.brainresbull.2011.08.002. Epub 2011 Aug 5.

Additional References at PubMed

PMID:14749425	PMID:15845084	PMID:15975920	PMID:17389603	PMID:17472960	PMID:17996222	PMID:20457227	PMID:21290411	PMID:22692600	PMID:22728873	PMID:23184880	PMID:23376485
PMID:26651291	PMID:26843113	PMID:29061393	PMID:29396549	PMID:32779334	PMID:38306928

Genomics

Comparative Map Data

Rgma
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	136,538,782 - 136,582,763 (+)	NCBI		GRCr8
mRatBN7.2	1	127,128,934 - 127,172,918 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	127,128,934 - 127,172,918 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	135,121,700 - 135,165,733 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	142,291,803 - 142,335,840 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	135,115,277 - 135,159,262 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	134,699,053 - 134,742,512 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	134,699,299 - 134,742,514 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	135,725,212 - 135,768,409 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	128,547,399 - 128,591,304 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	1	128,641,975 - 128,668,760 (+)	NCBI
Celera	1	119,260,496 - 119,304,476 (+)	NCBI		Celera
Cytogenetic Map	1	q31	NCBI

RGMA
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	15	93,035,271 - 93,089,211 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	15	93,035,271 - 93,089,211 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	15	93,578,501 - 93,632,440 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	15	91,387,641 - 91,433,437 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	15	91,387,640 - 91,433,437	NCBI
Celera	15	69,998,187 - 70,044,004 (-)	NCBI		Celera
Cytogenetic Map	15	q26.1	NCBI
HuRef	15	69,723,091 - 69,768,218 (-)	NCBI		HuRef
CHM1_1	15	93,427,333 - 93,473,451 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	15	90,797,572 - 90,851,558 (-)	NCBI		T2T-CHM13v2.0

Rgma
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	7	73,025,268 - 73,069,647 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	7	73,025,257 - 73,069,647 (+)	Ensembl		GRCm39 Ensembl
GRCm38	7	73,375,520 - 73,419,899 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	7	73,375,509 - 73,419,899 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	7	80,520,406 - 80,564,785 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	7	73,249,020 - 73,293,410 (+)	NCBI		MGSCv36	mm8
Celera	7	70,823,178 - 70,867,680 (+)	NCBI		Celera
Cytogenetic Map	7	D1	NCBI
cM Map	7	41.85	NCBI

Rgma
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955416	21,221,023 - 21,261,831 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955416	21,221,023 - 21,261,831 (-)	NCBI	ChiLan1.0	ChiLan1.0

RGMA
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	16	82,590,158 - 82,635,904 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	15	86,288,195 - 86,333,861 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	15	71,728,669 - 71,774,447 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	15	90,922,199 - 90,951,704 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	15	90,922,199 - 90,956,179 (-)	Ensembl	panpan1.1		panPan2

RGMA
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	3	47,044,342 - 47,089,923 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	3	47,061,910 - 47,089,294 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	3	49,744,736 - 49,788,688 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	3	47,453,705 - 47,497,710 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	3	47,453,784 - 47,498,695 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	3	46,971,723 - 47,015,658 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	3	47,203,068 - 47,247,025 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	3	47,534,393 - 47,578,334 (+)	NCBI		UU_Cfam_GSD_1.0

Rgma
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	136,541,660 - 136,581,389 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936483	9,766,275 - 9,793,001 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936483	9,753,112 - 9,792,817 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

RGMA
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	7	85,921,594 - 85,968,888 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	7	85,921,524 - 85,968,887 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	7	91,815,011 - 91,862,487 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

RGMA
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	29	11,592,929 - 11,638,955 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	29	11,592,604 - 11,638,860 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666059	35,022,501 - 35,068,477 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Rgma
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624768	10,751,991 - 10,778,050 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624768	10,739,674 - 10,778,036 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Rgma
155 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	649
Count of miRNA genes:	254
Interacting mature miRNAs:	336
Transcripts:	ENSRNOT00000068766
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
70225	Bp58	Blood pressure QTL 58	3.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	32356093	162846471	Rat
10059597	Bp377	Blood pressure QTL 377	3.42	0.025	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	32737458	199368955	Rat
2313402	Anxrr24	Anxiety related response QTL 24			aggression-related behavior trait (VT:0015014)	tameness/aggressiveness composite score (CMO:0002136)	1	48963584	144267916	Rat
1578654	Bss10	Bone structure and strength QTL 10	4		femur morphology trait (VT:0000559)	femoral neck cortical cross-sectional area (CMO:0001702)	1	49393172	159356837	Rat
634314	Niddm44	Non-insulin dependent diabetes mellitus QTL 44			blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	49393289	199050459	Rat
2298545	Neuinf8	Neuroinflammation QTL 8	4.6		nervous system integrity trait (VT:0010566)	spinal cord beta-2 microglobulin mRNA level (CMO:0002125)	1	57336763	151090257	Rat
1578780	Cm52	Cardiac mass QTL 52	3.3	0.0001	heart mass (VT:0007028)	heart wet weight (CMO:0000069)	1	81591954	219808434	Rat
738022	Anxrr13	Anxiety related response QTL 13	4.6	0.00039	locomotor behavior trait (VT:0001392)	number of 20 x 20 cm floor squares crossed into, out of or within a discrete space in an experimental apparatus (CMO:0001514)	1	83547917	128547917	Rat
724529	Cm16	Cardiac mass QTL 16	2.7		heart mass (VT:0007028)	calculated heart weight (CMO:0000073)	1	87580395	150700247	Rat
724521	Uae1	Urinary albumin excretion QTL 1	3.8	0.0001	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	1	90508614	173018436	Rat
1358902	Bw47	Body weight QTL 47	1.67		body mass (VT:0001259)	body weight (CMO:0000012)	1	90508614	180359386	Rat
1300153	Bp171	Blood pressure QTL 171	3.37		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	1	90664883	143200202	Rat
2293142	Bp314	Blood pressure QTL 314			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	92184926	137184926	Rat
724567	Tcas6	Tongue tumor susceptibility QTL 6	6.85		tongue integrity trait (VT:0010553)	number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)	1	92948896	144267916	Rat
1331793	Bp200	Blood pressure QTL 200	3.71601		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	94494440	172949803	Rat
1331751	Bp199	Blood pressure QTL 199	3.60022		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	1	94494440	181830018	Rat
1331749	Hrtrt11	Heart rate QTL 11	2.973		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	1	94494440	198211706	Rat
70209	Niddm23	Non-insulin dependent diabetes mellitus QTL 23	2.82		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	94494440	198324465	Rat
731168	Bp154	Blood pressure QTL 154	3.4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	94642644	214537671	Rat
61346	Rf2	Renal disease susceptibility QTL 2	3.7		urine protein amount (VT:0005160)	urine protein level (CMO:0000591)	1	99267916	144267916	Rat
61399	Tcat1	Tongue tumor resistance QTL 1	3.3		tongue integrity trait (VT:0010553)	number of squamous cell tumors of the tongue with diameter greater than 5 mm (CMO:0001879)	1	99267916	144267916	Rat
8655649	Arrd1	Age-related retinal degeneration QTL 1	4.89		retinal layer morphology trait (VT:0003727)	percentage of study population developing retinopathy during a period of time (CMO:0002453)	1	100357752	183970443	Rat
2317833	Alcrsp19	Alcohol response QTL 19	12.4	0.001	response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	1	100979852	145979852	Rat
1641897	Alcrsp1	Alcohol response QTL 1			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	1	100979852	145979852	Rat
2303591	Gluco41	Glucose level QTL 41	2		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	102168504	147168504	Rat
61370	Mcs3	Mammary carcinoma susceptibility QTL 3	2.15		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	1	102268556	147268556	Rat
1354623	Rf46	Renal function QTL 46	3.8		blood creatinine amount (VT:0005328)	plasma creatinine level (CMO:0000537)	1	102813953	151162766	Rat
1354591	Cm36	Cardiac mass QTL 36	4.1		heart left ventricle mass (VT:0007031)	calculated heart weight (CMO:0000073)	1	102813953	201278233	Rat
1354615	Cm32	Cardiac mass QTL 32	5.2		heart left ventricle mass (VT:0007031)	heart left ventricle wet weight (CMO:0000071)	1	102813953	201278233	Rat
1354606	Bp246	Blood pressure QTL 246	3.6		arterial blood pressure trait (VT:2000000)	pulse pressure (CMO:0000292)	1	102813953	218753816	Rat
9590300	Scort16	Serum corticosterone level QTL 16	4.39	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	1	103111621	148111621	Rat
8694370	Bw154	Body weight QTL 154	8.91	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	1	103111621	148111621	Rat
631496	Bp97	Blood pressure QTL 97	3.08		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	106047847	151047847	Rat
1300158	Bp173	Blood pressure QTL 173	3.48		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	1	115540693	185145286	Rat
7794788	Mcs32	Mammary carcinoma susceptibility QTL 32	2.61		mammary gland integrity trait (VT:0010552)	mammary tumor incidence/prevalence measurement (CMO:0000946)	1	115540693	238914717	Rat
631199	Cm23	Cardiac mass QTL 23	4.6	0.0004	heart left ventricle mass (VT:0007031)	heart left ventricle wet weight (CMO:0000071)	1	115585465	172949803	Rat
7421630	Bp362	Blood pressure QTL 362		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	118608292	241799120	Rat
2313060	Bss71	Bone structure and strength QTL 71	2.6	0.0001	long bone metaphysis morphology trait (VT:0000133)	tibia midshaft total cross-sectional area (CMO:0001715)	1	118944747	163944747	Rat
631205	Bp196	Blood pressure QTL 196	4	0.0001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	118944897	199050459	Rat
1598850	Bp297	Blood pressure QTL 297	2.1		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	121006655	166006655	Rat
1598866	Bp287	Blood pressure QTL 287	5.1		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	121006655	166006655	Rat
61442	Strs1	Sensitivity to stroke QTL 1	7.4		cerebrum integrity trait (VT:0010549)	post-insult time to onset of cerebrovascular lesion (CMO:0002343)	1	121767634	166767634	Rat
2293140	Bp313	Blood pressure QTL 313			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	121833674	166833674	Rat
2325726	Eae30	Experimental allergic encephalomyelitis QTL 30			nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis severity score (CMO:0001419)	1	123053310	128593844	Rat
631544	Bp84	Blood pressure QTL 84	5.6		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	123350408	181759564	Rat
1358189	Cstrr1	Cold stress response QTL 1		0.0001	catecholamine amount (VT:0010543)	urine norepinephrine level (CMO:0001629)	1	123350408	182418476	Rat
1641895	Bp298	Blood pressure QTL 298			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	123350408	182418476	Rat
1578770	Stresp23	Stress response QTL 23			kidney sympathetic nerve activity (VT:0004050)	stimulated renal sympathetic nerve activity to basal renal sympathetic nerve activity ratio (CMO:0001786)	1	123350408	182418476	Rat
631549	Bp89	Blood pressure QTL 89	5.7		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	123350581	201284552	Rat
631570	Bp94	Blood pressure QTL 94		0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	123479780	142990467	Rat
634348	Bp138	Blood pressure QTL 138			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	125611501	168883176	Rat
9685799	Bp375	Blood pressure QTL 375			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	125611501	170611501	Rat
631654	Bp107	Blood pressure QTL 107			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	125611501	170611501	Rat
9685802	Bp376	Blood pressure QTL 376			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	126540680	171540680	Rat

Markers in Region

AA819234

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	1	127,172,765 - 127,172,858 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	134,742,359 - 134,742,451	NCBI	Rnor6.0
Rnor_5.0	1	135,768,256 - 135,768,348	UniSTS	Rnor5.0
RGSC_v3.4	1	128,591,152 - 128,591,244	UniSTS	RGSC3.4
Celera	1	119,304,324 - 119,304,416	UniSTS
RH 3.4 Map	1	982.2	UniSTS
Cytogenetic Map	1	q31	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium		17						3	66	16	35	3
Low	3	26	31	15	19	15	8	8	8	19	6	8	8
Below cutoff			25	25		25

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001107524	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008759521	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH473980	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000001	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSRNOT00000068766 ⟹ ENSRNOP00000061067

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	1	127,128,934 - 127,172,918 (+)	Ensembl
Rnor_6.0 Ensembl	1	134,699,299 - 134,742,514 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000076446

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	1	134,715,209 - 134,741,356 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000118102 ⟹ ENSRNOP00000090452

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	1	127,159,261 - 127,172,918 (+)	Ensembl

RefSeq Acc Id:

NM_001107524 ⟹ NP_001100994

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	136,538,782 - 136,582,763 (+)	NCBI
mRatBN7.2	1	127,128,934 - 127,172,918 (+)	NCBI
Rnor_6.0	1	134,699,053 - 134,742,511 (+)	NCBI
Rnor_5.0	1	135,725,212 - 135,768,409 (+)	NCBI
RGSC_v3.4	1	128,547,399 - 128,591,304 (+)	RGD
Celera	1	119,260,496 - 119,304,476 (+)	RGD

Sequence:

show sequence

ACGCCGCGCTCAGCGGTGGCGGTGGCGGCGACAGGCCGGGCGAGGCAGCAGGTTAGCCCGGGCC
GCCCTACTCTGCAGGCTTCTCGGAAGTACAAGCTGCGCCGCCCGAGCCCTGCGCCCGGGAAGCA
CTGGCCAGCGGGCCGCTCCTGAGGCCCGCTCCTCCAGGCGCTCGCAGGCATGCAGCCGGGGAGC
AGGCGGAGTGCCCCGGGCCGCTACTGAGTCCGCGGAGCTGAGGGGATCAGCTCCAGCCGTGCCC
CTCCCACCTCACCCAGGGCCCCACGAGCGACCGCCCTACACCTGGTCTTCGCGCGCAGCCCCGC
CAGTGCCAACCCCCCGCGGGCTGGAGGGGCTCATGCAGCCGCCAAGGGAGAGGCTAGTGGTAAC
AGGCCGAGCTGGATGGATGGGTATGGGGAGAGGGGCAGGACGTTCAGCCCTGGGATTGTGGCCG
ACCCTCGCCTTCCTTCTCTGCAGCTTTCCCGCAGCTATCTCTCCCTGCAAGATCCTCAAGTGCA
ACTCTGAGTTCTGGAGCGCCACGTCGTCAGGCAGCCACGCCCCTGCCTCTGACGACGTGCCCGA
GTTCTGTGCTGCCCTGCGCACCTACGCCCTGTGCACGCGACGGACAGCCCGCACCTGCCGGGGC
GACCTGGCTTACCACTCGGCTGTCCATGGCATAGAGGACCTCATGAGCCAGCACAACTGCTCCA
AGGATGGCCCCACCTCACAGCCTCGAGTGCGCACGCTCCCGCCAGCTGGGGACAGCCAGGAGCG
CTCAGATAGCCCCGAGATCTGCCACTATGAGAAGAGTTTCCACAAGCACTCAGCTGCCCCCAAC
TACACTCACTGCGGCCTCTTTGGGGACCCACACCTCAGGACTTTCACAGACCACTTCCAGACAT
GTAAGGTGCAAGGCGCTTGGCCTCTCATCGACAATAATTACCTGAACGTGCAGGTCACCAATAC
ACCTGTGCTGCCCGGCTCTGCCGCCACTGCCACCAGCAAGCTCACCATCATCTTCAAGAACTTC
CAAGAGTGTGTGGACCAGAAAGTATACCAAGCCGAGATGGACGAGCTTCCGTCCGCCTTTGCCG
ATGGCTCCAAAAACGGTGGAGATAAACACGGAGCCAACAGCCTGAAGATCACAGAGAAGGTGTC
AGGCCAGCACGTGGAGATCCAGGCCAAGTACATCGGCACCACCATCGTGGTGAGACAGGTGGGC
CGCTACCTGACCTTCGCCGTCCGGATGCCCGAGGAGGTAGTCAACGCCGTGGAGGACCGTGACA
GCCAAGGCCTCTACCTCTGCCTGCGGGGCTGCCCGCTCAACCAGCAGATCGACTTCCAGGCTTT
CCGTGCCAACGCCGAGAGCCCTCGCAGGCCAGCAGCTGCCAGCCCCTCTCCTGTGGTCCCCGAG
ACATTTCCGTACGAGACAGCTGTGGCCAAGTGCAAAGAGAAGCTGCCTGTAGAAGACTTGTACT
ACCAGGCCTGTGTCTTCGACCTCCTCACGACTGGCGACGTGAACTTCACGCTGGCCGCCTACTA
TGCTTTGGAGGATGGCAAGATGCTCCACTCCAACAAGGACAAGCTACACCTGTTTGAAAGGACT
CGGGAGCTGCCTGGCGCTGTGGCCGCTGCAGCATTTCCCTTGGCCCCCGAGATGCTCCCGGGCA
CCGTCACACTTCTGGTCCTGCTGCCTCTGTTCTGGTAGACGTTTGGCCATGTAGGATACAAAGG
AGGGTATAGACTCTGCCCTGAGCCTTGGGCTCCTGCCCTTGGCTTCTCCTTCGTCTGAGGGTCC
AAGTCAGCATCAGGATGCAGCCCAGCCGGTGGGCTTCCTGTGACCCAGTGTTTTCAGCAGCGGA
GGTGGCCTCTAGCTGACGGCCTGAACATGGTGCCCTCAGAGCCGTCCTCAAATGTTATGGCCAG
GGCTAAGGGCGCGGGACAGCTCTCCCCTCTCGATTAGTGCACGCGACAAGGTTGTGGTGATTGA
TGCTGTGTTTTTGTGACAGTAGAGTTGTGTGAGGGAGAGCAGCTCCCTCCACCCCGACCCCACC
GTGTGAATGTTCGAACCAGAGCCCCACCCCTAAGCTGAAGCCCCACCCCCACCACCAGAGAGAC
ACTGGGAAAGTCGGCTCCTTCCACACTCTCACAATGCACTGAGACAGGCCCGGCTGACTGCTGC
ACACCCGCTCTGGGGCCTCCTGTCCCCTCCCACACACGCGCACACACTGTTACACAAGCACACT
CGCACACACTAAGCCCGTGGGGACACCTCGAGACCGCCACATCAGTAGGGCGGAAGCATCTACG
GATCCCCAGAGGGCCTTGCTCAGTATCTTTAGCAAATGGATGTAACCTTGTAGCCAGTGGGCTA
TGTCCTCTTGGTACCACCTACCCAGTGCTACGTACCCAGAGACGGTCCTGTGCATCCAGCTACT
GTGGATGTGATTGAGGTGCTGCTTCCGAGGACCTGCCTGGAAAGGCCCACAGTTGAAGGGAGGG
TGTGTTTTGGCCTGAGGTCTAAGCAGTACCTCTCATGGGCTCAGATCCCGGCTCCACCCTCTGC
CCCTCTCCCATTGCACTTAAGAAATCAAAGTGCTTGGTTCTGAATGTTACAACAGAGACGTGAT
CCTCCAGTTCCTGCCATCGTTGCCCCTACCCTATCCTTCACCCCTACCCTTGCCCCCCACCAGC
AGAGGGGCCCTGGGACCTCAGGGCATGAGCAGCAGACCCAGTGGATAGGGCCAGCTGGTCTGCC
CTGTCCTCTGCTCTCTTTCTCTTGCCTCTTAGATTCCTGGCTGCTGGTCAGCAGCTCTGCTCCC
CAACCCCTTTGTCTGCATTTCTTTGTGGGGGTTGGGGGGAGCATCATCTAAGAGGCCTTCCTGC
ACCCTGTACCCTGGCAGGCTCTCCTCCCACTAGAACCTTCTTTCAACTCTGGCCACAGCCAGAG
GCCTGTCACTGGGAGCCTAGGTCTCCTTCAGCTCAAGGCGAGAGTCCACCCACAGAGCCCAGAG
CCATTCCCAACTCTGCTGCTGTTCCAGAGGCCCCCCAAGGGACCAGCACAACAGAACAGCCAGC
CCCCTGGGCCACCCAGCCAGCGGCCCTGCAGAGCCTACCCTAGCCCCACTCAATGTTTATAGCA
GCCCTGTGCTGCTCCCCAGGGACCTCTCCATACACTGGCCAGGAGGCTGCAGAACCTGCCTCTC
CCTCCCAGAGGTCCCAACCCCTGCCAAAACCACATGGGTAGCTGGGAGGGGTCAGCTCCGCCCC
TCTCCTCCCTGCTGGTTTTTTAGCTATCCCTATGTTGGAAGTAAAAGAGTCGAAGCACTTTATT
TTGGTTGTGTTTGATCACGTTCTGCTTGGAAGTGGGGACCCCTCACTGAGTCCACATGTCTGCG
GCCTGTGTGGAGCACCACTGCGTGTACATACTGTAAATTATTTATTAATGGCTAAATGCAAGTA
AAGTTTGGTTTGTTTTGTTATTTTCTTTT

hide sequence

Protein Sequences


Protein RefSeqs	NP_001100994	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDM08503	(Get FASTA)	NCBI Sequence Viewer
	EDM08504	(Get FASTA)	NCBI Sequence Viewer
	EDM08505	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000061067
	ENSRNOP00000061067.1
	ENSRNOP00000090452.1

RefSeq Acc Id:

NP_001100994 ⟸ NM_001107524

- UniProtKB:

D4A188 (UniProtKB/TrEMBL), A6JBX6 (UniProtKB/TrEMBL), A6JBX8 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MQPPRERLVVTGRAGWMGMGRGAGRSALGLWPTLAFLLCSFPAAISPCKILKCNSEFWSATSSG
SHAPASDDVPEFCAALRTYALCTRRTARTCRGDLAYHSAVHGIEDLMSQHNCSKDGPTSQPRVR
TLPPAGDSQERSDSPEICHYEKSFHKHSAAPNYTHCGLFGDPHLRTFTDHFQTCKVQGAWPLID
NNYLNVQVTNTPVLPGSAATATSKLTIIFKNFQECVDQKVYQAEMDELPSAFADGSKNGGDKHG
ANSLKITEKVSGQHVEIQAKYIGTTIVVRQVGRYLTFAVRMPEEVVNAVEDRDSQGLYLCLRGC
PLNQQIDFQAFRANAESPRRPAAASPSPVVPETFPYETAVAKCKEKLPVEDLYYQACVFDLLTT
GDVNFTLAAYYALEDGKMLHSNKDKLHLFERTRELPGAVAAAAFPLAPEMLPGTVTLLVLLPLF
W

hide sequence

RefSeq Acc Id:

ENSRNOP00000061067 ⟸ ENSRNOT00000068766

RefSeq Acc Id:

ENSRNOP00000090452 ⟸ ENSRNOT00000118102

Protein Domains

Repulsive guidance molecule C-terminal Repulsive guidance molecule N-terminal

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D4A188-F1-model_v2	AlphaFold	D4A188	1-449	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13690113

Promoter ID:

EPDNEW_R638

Type:

initiation region

Name:

Rgma_1

Description:

repulsive guidance molecule family member A

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	1	134,715,269 - 134,715,329	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1311983	AgrOrtholog
BioCyc Gene	G2FUF-58894	BioCyc
Ensembl Genes	ENSRNOG00000012874	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000068766	ENTREZGENE
	ENSRNOT00000068766.3	UniProtKB/TrEMBL
	ENSRNOT00000118102.1	UniProtKB/TrEMBL
Gene3D-CATH	Mog1/PsbP, alpha/beta/alpha sandwich	UniProtKB/TrEMBL
InterPro	RGM	UniProtKB/TrEMBL
	RGM_C	UniProtKB/TrEMBL
	RGM_N	UniProtKB/TrEMBL
KEGG Report	rno:308739	UniProtKB/TrEMBL
NCBI Gene	308739	ENTREZGENE
PANTHER	PTHR31428	UniProtKB/TrEMBL
	PTHR31428:SF4	UniProtKB/TrEMBL
Pfam	RGM_C	UniProtKB/TrEMBL
	RGM_N	UniProtKB/TrEMBL
PhenoGen	Rgma	PhenoGen
RatGTEx	ENSRNOG00000012874	RatGTEx
UniProt	A0A8I6ACJ0_RAT	UniProtKB/TrEMBL
	A6JBX6	ENTREZGENE, UniProtKB/TrEMBL
	A6JBX8	ENTREZGENE, UniProtKB/TrEMBL
	D4A188	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2018-01-18	Rgma	repulsive guidance molecule BMP co-receptor a	Rgma	repulsive guidance molecule family member A	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2013-11-19	Rgma	repulsive guidance molecule family member A	Rgma	RGM domain family, member A	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-04-30	Rgma	RGM domain family, member A	Rgma_predicted	RGM domain family, member A (predicted)	'predicted' is removed	2292626	APPROVED
2005-01-12	Rgma_predicted	RGM domain family, member A (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Annotations - PID (archival)

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Imported Disease Annotations - ClinVar

Imported Annotations - PID (archival)