| URN | urn:agi-llid:27158 |
|---|---|
| Total Entities | 0 |
| Connectivity | 5 |
| Name | Ndor1 |
| Description | NADPH dependent diflavin oxidoreductase 1 |
| Notes | This gene encodes an NADPH-dependent diflavin reductase that contains both flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD) binding domains. The encoded protein catalyzes the transfer of electrons from NADPH through FAD and FMN cofactors to potential redox partners. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2012] |
| GO Molecular Function | oxidoreductase activity |
|---|---|
| oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen | |
| NADPH-hemoprotein reductase activity | |
| flavin adenine dinucleotide binding | |
| NADP binding | |
| FMN binding | |
| iron ion binding |
| GO Cellular Component | cytoplasm |
|---|---|
| cytosol | |
| perinuclear region of cytoplasm | |
| intermediate filament cytoskeleton | |
| nucleus |
| GO Biological Process | small molecule metabolic process |
|---|---|
| oxidation-reduction process | |
| cell death | |
| cellular response to menadione |
| Pathway | cytosolic iron-sulfur cluster protein assembly pathway |
|---|
| Group | small molecule metabolic process |
|---|---|
| oxidation-reduction process | |
| oxidoreductase activity | |
| oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen | |
| NADPH-hemoprotein reductase activity | |
| cell death | |
| cellular response to menadione | |
| flavin adenine dinucleotide binding | |
| NADP binding | |
| FMN binding | |
| iron ion binding | |
| cytoplasm | |
| cytosol | |
| perinuclear region of cytoplasm | |
| intermediate filament cytoskeleton | |
| nucleus |
| LocusLink ID | 27158 |
|---|---|
| 78797 | |
| 311799 |
| Cell Localization | Cytoplasm |
|---|---|
| Perinuclear region |
| GO ID | 0010181 |
|---|---|
| 0050661 | |
| 0003958 | |
| 0050660 | |
| 0005506 | |
| 0016491 | |
| 0016709 | |
| 0008219 | |
| 0036245 | |
| 0055114 | |
| 0044281 | |
| 0005737 | |
| 0005829 | |
| 0045111 | |
| 0005634 | |
| 0048471 |
| Alias | NR1 |
|---|---|
| bA350O14.9 | |
| RP11-350O14.11-001 | |
| NADPH-dependent diflavin oxidoreductase 1 | |
| NADPH-dependent FMN and FAD-containing oxidoreductase | |
| Ndor | |
| 4930447P04Rik | |
| RP23-132N23.13-001 | |
| RP23-132N23.13 | |
| RP11-350o14.11 | |
| OTTMUSP00000012710 | |
| NDOR1 | |
| NADPH dependent FMN and FAD containing oxidoreductase | |
| nadph dependent diflavin oxidoreductase I | |
| nadph dependent diflavin oxidoreductase 1 | |
| LOC377839 | |
| OTTHUMP00000064742 | |
| NADP(H) dependent FMN and FAD containing oxidoreductase | |
| LOC389822 | |
| LOC648245 | |
| MGC138148 | |
| NAD(P)H dependent diflavin oxidoreductase I | |
| NAD(P)H dependent FMN and FAD containing oxidoreductase | |
| NADP(H) dependent diflavin oxidoreductase 1 | |
| NADP(H) dependent diflavin oxidoreductase I | |
| NAD(P)H dependent diflavin oxidoreductase 1 |
| Mouse chromosome position | 2 |
|---|
| OMIM ID | 606073 |
|---|
| Rat chromosome position | 3p13 |
|---|
| Hugo ID | 29838 |
|---|
| Human chromosome position | 9q34.3 |
|---|
| Swiss-Prot Accession | Q9UHB4 |
|---|---|
| D3YTG6 | |
| A2AI05 | |
| D4ABT4 | |
| D3YTH9 | |
| Q5VSG4 | |
| Q86US9 | |
| Q96BC6 | |
| Q3TQZ6 | |
| Q80WC5 |
| Unigene ID | Hs.512564 |
|---|---|
| Mm.40020 | |
| Rn.82950 |
| KEGG ID | hsa:27158 |
|---|---|
| mmu:78797 | |
| rno:311799 |
| Swiss-Prot ID | NDOR1_HUMAN |
|---|---|
| NDOR1_MOUSE |
| EC Number | 1.6.-.- |
|---|
| Ensembl ID | ENSG00000188566 |
|---|---|
| ENSP00000343344 | |
| ENST00000344894 | |
| ENSP00000360576 | |
| ENST00000371521 | |
| ENSMUSG00000006471 | |
| ENSMUSP00000097903 | |
| ENSMUST00000100329 | |
| ENSMUSP00000109989 | |
| ENSMUST00000114349 | |
| ENSRNOG00000010616 | |
| ENSRNOP00000014445 | |
| ENSRNOT00000014445 |
| Homologene ID | 7144 |
|---|
| Organism | Homo sapiens |
|---|---|
| Mus musculus | |
| Rattus norvegicus |
| MGI ID | 1926047 |
|---|
| RGD ID | 1308479 |
|---|
| MedScan ID | 27158 |
|---|