| URN | urn:agi-llid:3313 |
|---|---|
| Total Entities | 0 |
| Connectivity | 421 |
| Name | Hspa9 |
| Description | heat shock 70kDa protein 9 (mortalin) |
| Notes | This gene encodes a member of the heat shock protein 70 gene family. The encoded protein is primarily localized to the mitochondria but is also found in the endoplasmic reticulum, plasma membrane and cytoplasmic vesicles. This protein is a heat-shock cognate protein. This protein plays a role in cell proliferation, stress response and maintenance of the mitochondria. A pseudogene of this gene is found on chromosome 2.[provided by RefSeq, May 2010] |
| GO Molecular Function | unfolded protein binding |
|---|---|
| enzyme binding | |
| heat shock protein binding | |
| fibroblast growth factor binding | |
| nucleotide binding | |
| ATP binding |
| GO Cellular Component | nucleolus |
|---|---|
| mitochondrial nucleoid | |
| cell surface | |
| cytoplasm | |
| mitochondrion | |
| nucleus |
| GO Biological Process | negative regulation of apoptotic process |
|---|---|
| protein export from nucleus | |
| protein targeting to mitochondrion | |
| response to toxic substance | |
| cellular response to interleukin-1 | |
| cellular protein metabolic process | |
| protein folding |
| Pathway | Mitochondrial Protein Transport |
|---|---|
| mitochondrial iron-sulfur cluster protein biogenesis pathway |
| Group | Protein folding |
|---|---|
| negative regulation of apoptotic process | |
| protein export from nucleus | |
| protein targeting to mitochondrion | |
| response to toxic substance | |
| cellular response to interleukin-1 | |
| cellular protein metabolic process | |
| protein folding | |
| unfolded protein binding | |
| enzyme binding | |
| heat shock protein binding | |
| fibroblast growth factor binding | |
| nucleotide binding | |
| ATP binding | |
| nucleolus | |
| mitochondrial nucleoid | |
| cell surface | |
| cytoplasm | |
| mitochondrion | |
| nucleus | |
| Secreted proteins | |
| Biofluids assayable substances |
| LocusLink ID | 3313 |
|---|---|
| 15526 | |
| 291671 |
| Cell Localization | Cytoplasm |
|---|---|
| Mitochondrion | |
| Nucleus | |
| Nucleolus |
| GO ID | 0005524 |
|---|---|
| 0019899 | |
| 0051082 | |
| 0044267 | |
| 0043066 | |
| 0006611 | |
| 0006457 | |
| 0006626 | |
| 0005737 | |
| 0042645 | |
| 0005739 | |
| 0005730 | |
| 0017134 | |
| 0031072 | |
| 0000166 | |
| 0005634 | |
| 0071347 | |
| 0009636 | |
| 0009986 |
| Alias | CSA |
|---|---|
| MOT | |
| MOT2 | |
| GRP75 | |
| PBP74 | |
| GRP-75 | |
| HSPA9B | |
| MTHSP75 | |
| stress-70 protein, mitochondrial | |
| mortalin-2 | |
| p66-mortalin | |
| mortalin, perinuclear | |
| heat shock 70kD protein 9B | |
| peptide-binding protein 74 | |
| 75 kDa glucose-regulated protein | |
| 74kDa | |
| Hsc74 | |
| Hsp74 | |
| Mot-2 | |
| Hsp74a | |
| Hspa9a | |
| Mthsp70 | |
| Mortalin | |
| p66 MOT | |
| C3H-specific antigen | |
| heat shock protein 9A | |
| heat shock protein, A | |
| heat shock 70 kDa protein 9 | |
| heat shock protein cognate 74 | |
| heat shock protein, 74 kDa, A | |
| GRP 75 | |
| heat shock 70kDa protein 9A | |
| mt-HSP70 | |
| Hsp74-ps1 | |
| mitochondrial Stress-70 protein | |
| mitochondrial heat shock protein 70 | |
| MGC4500 | |
| LOC91471 | |
| HSPA9 | |
| Hsp74b | |
| mortalin II | |
| stress-70 protein | |
| perinuclear mortalin | |
| heat shock 70kDa protein 9 | |
| Hsp74-ps I | |
| 70 kDa heat shock protein 9 | |
| 70 kDa heat shock protein 9B | |
| 75 kDa glucose regulated protein | |
| dnaK-type molecular chaperone grp75 | |
| heat shock 70kD protein 9 | |
| heat shock 70kD protein 9B (mortalin-2) | |
| heat shock 70kDa protein 9 (mortalin) | |
| heat shock, 74 kDa, pseudogene | |
| heat shock protein, 74 kDa, pseudogene I | |
| heat shock 70kDa protein 9B | |
| heat shock protein 9B (mortalin-2) | |
| heat shock protein 9b | |
| heat shock protein 9 | |
| heat shock 70kDa protein 9B (mortalin-2) | |
| heat shock protein, 74 kDa, pseudogene 1 |
| Mouse chromosome position | 18 18.8 cM |
|---|
| OMIM ID | 600548 |
|---|
| Rat chromosome position | 18p12 |
|---|
| Hugo ID | 5244 |
|---|
| Human chromosome position | 5q31.1 |
|---|
| Swiss-Prot Accession | P38646 |
|---|---|
| P38647 | |
| F1M953 | |
| P48721 | |
| B2RCM1 | |
| P30036 | |
| P31932 | |
| Q1HB43 | |
| Q53H23 | |
| Q6GU03 | |
| Q9BWB7 | |
| Q9UC56 | |
| Q3TW93 | |
| Q3UVN1 | |
| Q3V015 | |
| Q7TSZ0 | |
| Q9CQ05 |
| PIR ID | B48127 |
|---|---|
| S39839 |
| Unigene ID | Hs.184233 |
|---|---|
| Mm.209419 | |
| Rn.7535 |
| KEGG ID | hsa:3313 |
|---|---|
| mmu:15526 | |
| rno:291671 |
| Swiss-Prot ID | GRP75_HUMAN |
|---|---|
| GRP75_MOUSE |
| Ensembl ID | ENSG00000113013 |
|---|---|
| ENSP00000297185 | |
| ENST00000297185 | |
| ENSMUSG00000024359 | |
| ENSMUSP00000025217 | |
| ENSMUST00000025217 |
| Homologene ID | 39452 |
|---|
| Organism | Homo sapiens |
|---|---|
| Mus musculus | |
| Rattus norvegicus |
| MGI ID | 96245 |
|---|
| RGD ID | 1311806 |
|---|
| MedScan ID | 3313 |
|---|