| URN | urn:agi-llid:51218 |
|---|---|
| Total Entities | 0 |
| Connectivity | 85 |
| Name | Glrx5 |
| Description | glutaredoxin 5 |
| Notes | This gene encodes a mitochondrial protein, which is evolutionarily conserved. It is involved in the biogenesis of iron-sulfur clusters, which are required for normal iron homeostasis. Mutations in this gene are associated with autosomal recessive pyridoxine-refractory sideroblastic anemia. [provided by RefSeq, May 2010] |
| GO Molecular Function | protein disulfide oxidoreductase activity |
|---|---|
| electron carrier activity | |
| metal ion binding | |
| iron-sulfur cluster binding | |
| 2 iron, 2 sulfur cluster binding |
| GO Cellular Component | mitochondrion |
|---|---|
| nucleus |
| GO Biological Process | hemopoiesis |
|---|---|
| cell redox homeostasis |
| Pathway | mitochondrial iron-sulfur cluster protein biogenesis pathway |
|---|
| Group | hemopoiesis |
|---|---|
| protein disulfide oxidoreductase activity | |
| cell redox homeostasis | |
| electron carrier activity | |
| metal ion binding | |
| iron-sulfur cluster binding | |
| 2 iron, 2 sulfur cluster binding | |
| mitochondrion | |
| nucleus |
| LocusLink ID | 51218 |
|---|---|
| 73046 | |
| 362776 |
| Cell Localization | Mitochondrion |
|---|
| GO ID | 0051537 |
|---|---|
| 0009055 | |
| 0046872 | |
| 0015035 | |
| 0045454 | |
| 0030097 | |
| 0005739 | |
| 0005634 | |
| 0051536 |
| Alias | GRX5 |
|---|---|
| FLB4739 | |
| PR01238 | |
| PRO1238 | |
| C14orf87 | |
| glutaredoxin-related protein 5, mitochondrial | |
| glutaredoxin 5 homolog | |
| monothiol glutaredoxin-5 | |
| AU020725 | |
| 2310004O13Rik | |
| 2900070E19Rik | |
| RGD1308383 | |
| MGC14129 | |
| GLRX5 | |
| RIKEN cDNA 2310004O13 gene | |
| glutaredoxin 5 homolog (S. cerevisiae) | |
| glutaredoxin 5 | |
| chromosome 14 open reading frame 87 |
| Mouse chromosome position | 12 |
|---|
| OMIM ID | 609588 |
|---|---|
| 205950 |
| Rat chromosome position | 6q32 |
|---|
| Hugo ID | 20134 |
|---|
| Human chromosome position | 14q32.13 |
|---|
| Swiss-Prot Accession | Q86SX6 |
|---|---|
| Q80Y14 | |
| D4ADD7 | |
| Q0X088 | |
| Q3YML0 | |
| Q86WY3 | |
| Q8IZ54 | |
| Q3YML1 | |
| Q9D6E9 |
| Unigene ID | Hs.744943 |
|---|---|
| Mm.29128 | |
| Mm.490286 | |
| Rn.104008 |
| KEGG ID | hsa:51218 |
|---|---|
| mmu:73046 | |
| rno:362776 |
| Swiss-Prot ID | GLRX5_HUMAN |
|---|---|
| GLRX5_MOUSE |
| Ensembl ID | ENSMUSG00000021102 |
|---|---|
| ENSMUSP00000021522 | |
| ENSMUST00000021522 | |
| ENSRNOG00000004206 | |
| ENSRNOP00000005781 | |
| ENSRNOT00000005781 |
| Homologene ID | 31984 |
|---|
| Organism | Homo sapiens |
|---|---|
| Mus musculus | |
| Rattus norvegicus |
| MGI ID | 1920296 |
|---|
| RGD ID | 1308383 |
|---|
| MedScan ID | 51218 |
|---|