| URN | urn:agi-llid:683 |
|---|---|
| Total Entities | 0 |
| Connectivity | 80 |
| Name | Bst1 |
| Description | bone marrow stromal cell antigen 1 |
| Notes | Bone marrow stromal cell antigen-1 is a stromal cell line-derived glycosylphosphatidylinositol-anchored molecule that facilitates pre-B-cell growth. The deduced amino acid sequence exhibits 33% similarity with CD38. BST1 expression is enhanced in bone marrow stromal cell lines derived from patients with rheumatoid arthritis. The polyclonal B-cell abnormalities in rheumatoid arthritis may be, at least in part, attributed to BST1 overexpression in the stromal cell population. [provided by RefSeq, Jul 2008] |
| GO Molecular Function | hydrolase activity |
|---|---|
| NAD+ nucleosidase activity |
| GO Cellular Component | membrane |
|---|---|
| anchored component of membrane | |
| extrinsic component of membrane | |
| plasma membrane |
| GO Biological Process | humoral immune response |
|---|---|
| multicellular organismal development |
| Pathway | nicotinamide adenine nucleotide utilization pathway |
|---|
| Group | CD38 |
|---|---|
| humoral immune response | |
| multicellular organismal development | |
| hydrolase activity | |
| NAD+ nucleosidase activity | |
| membrane | |
| anchored component of membrane | |
| extrinsic component of membrane | |
| plasma membrane | |
| Secreted proteins |
| LocusLink ID | 683 |
|---|---|
| 12182 | |
| 81506 |
| Cell Localization | Plasma membrane |
|---|---|
| Cell membrane |
| GO ID | 0003953 |
|---|---|
| 0006959 | |
| 0007275 | |
| 0031225 | |
| 0019898 | |
| 0005886 | |
| 0016787 | |
| 0016020 |
| Alias | CD157 |
|---|---|
| ADP-ribosyl cyclase 2 | |
| BST-1 | |
| cADPr hydrolase 2 | |
| NAD(+) nucleosidase | |
| bone marrow stromal antigen 1 | |
| cyclic ADP-ribose hydrolase 2 | |
| Bp3 | |
| BP-3 | |
| Ly65 | |
| Bsta1 | |
| 114/A10 | |
| A530073F09 | |
| ly-65 | |
| antigen BP3 | |
| BP-3 alloantigen | |
| leukocyte antigen 65 | |
| OTTHUMP00000217617 | |
| CADPR hydrolase II | |
| Cyclic ADP-ribose hydrolase II | |
| OTTMUSP00000033126 | |
| CD157 antigen | |
| Bsta I | |
| antigen CD157 | |
| alloantigen BP-3 | |
| Bst1 | |
| Bst I | |
| bone marrow stromal cell antigen 1 | |
| bone marrow stromal cell antigen I | |
| BP-3 antigen | |
| Bone marrow stromal antigen I |
| Mouse chromosome position | 5 23.84 cM |
|---|
| OMIM ID | 600387 |
|---|
| Rat chromosome position | 14q21 |
|---|
| Hugo ID | 1118 |
|---|
| Human chromosome position | 4p15 |
|---|
| Swiss-Prot Accession | Q10588 |
|---|---|
| Q1XII0 | |
| Q64277 | |
| Q63072 | |
| Q8BRY3 | |
| B2R6A2 | |
| Q5U0K0 | |
| Q96EN3 |
| PIR ID | JC2541 |
|---|---|
| JC4390 | |
| I59301 |
| Unigene ID | Hs.720344 |
|---|---|
| Mm.246332 | |
| Rn.10728 |
| KEGG ID | hsa:683 |
|---|---|
| mmu:12182 | |
| rno:81506 |
| Swiss-Prot ID | BST1_MOUSE |
|---|---|
| BST1_RAT | |
| BST1_HUMAN |
| EC Number | 3.2.2.5 |
|---|
| Ensembl ID | ENSG00000109743 |
|---|---|
| ENSP00000265016 | |
| ENST00000265016 | |
| ENSMUSG00000029082 | |
| ENSMUSP00000098796 | |
| ENSMUST00000101237 | |
| ENSRNOG00000003064 | |
| ENSRNOP00000004094 | |
| ENSRNOT00000004094 |
| Homologene ID | 3198 |
|---|
| Organism | Homo sapiens |
|---|---|
| Mus musculus | |
| Rattus norvegicus |
| MGI ID | 105370 |
|---|
| RGD ID | 620344 |
|---|
| MedScan ID | 683 |
|---|