Small Molecule NADPH

URN	urn:agi-cas:53-57-6
Total Entities	9
Connectivity	1713
Name	NADPH

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ChildConcepts	NADH
	NAD+
	NADP+
	carba-NAD
	Deaminocozymase
	3-Apadn
	NFDH
	3'-phospho-ADP
	2'-Deoxy NAD

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Pathway	Neurotoxin-Induced Parkinson's Disease
	Role of Polyol Pathway in Diabetic Microangiopathy
	Peripheral Tissue Microangiopathy in Insulin Resistance
	Pancreatic Beta-cell Death in Diabetes Mellitus Type 2
	Defective Clearance of Apoptotic Keratinocytes in Systemic Lupus Erythematosus
	Hemoglobin Reduction and Leukocyte Adhesion Initiate Vasospasm
	CFTR Up-regulates the Oxidative Stress in Airway Epithelium in Cystic Fibrosis
	Diabetes-Induced Cataract
	Age-Related Cataract
	Tricarboxylic acid cycle
	Pentose-phosphate shunt
	Mannose metabolism
	Serine and Glycine metabolism
	Tryptophan metabolism
	Phenylalanine and Tyrosine metabolism
	Ser/Gly/Thr/Cys metabolism
	Lysine metabolsm
	Urea cycle and arginine metabolism
	Glu/Gln/Pro metabolsm
	Methionine metabolism
	Purine metabolism
	Pyrimidine metabolism
	Nicotinate and nicotinamide metabolism
	Pterine biosynthesis
	Folate biosynthesis
	Heme oxidation
	Bile acids metabolism
	Biosynthesis of cholesterol
	Metabolism of glucocorticoids and mineralcorticoids
	Metabolism of estrogens and androgens
	Arachidonic acid metabolism
	Metabolism of triacylglycerols
	Sphingolipid metabolism
	ROS metabolism
	Fatty acid oxidation
	Metabolism of glycerophospholipids and ether lipids
	Fatty acid biosynthesis
	Bile acid metabolism (alternative pathway)
	Galactose metabolism
	Ascorbate biosyntesis
	Pyruvate metabolism
	L-sugars oxidation
	Vitamin A (retinol) metabolism and visual cycle
	Glutathione metabolism
	Malonate, propanoate and beta-alanine metabolism
	Riboflavin metabolism
	Caffeine metabolism
	Selencompound biosynthesis
	Ethanol metabolism
	Omega-3-fatty acid metabolism
	Glyoxylate and glycerate metabolism
	D-amino acid metabolism
	Mevalonate pathway
	Omega-6-fatty acid metabolism
	Ubiquinoine biosynthesis
	Ubiquinoine biosynthesis in humans
	Ubiquinoine biosynthesis in rats
	Cholesterol catabolism
	Capecitabine and Fluorafur metabolism
	ROS in Neutrophil-Mediated Cell Damage
	altered retinoid cycle metabolic pathway
	insulin secretion pathway
	altered insulin secretion pathway
	steroid hormone biosynthetic pathway
	testosterone biosynthetic pathway
	insulin secretion pathway
	altered insulin secretion pathway
	nicotinamide adenine dinucleotide metabolic pathway

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Group	Biofluids assayable substances

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Source	ChemIDplus

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Alias	[4S-(2)H]NADP(H)
	[4S-(2)H]NAD(P)H
	reduced nadide phosphate
	reduced Cozymase II
	reduced nicotinadenine dinucleotide phosphate
	Reduced nicotinamide adenine diphosphate
	Reduced triphosphopyridine nucleotide
	Triphosphopyridine nucleotide reduced
	reduced Coenzyme II
	reduced form nicotinamide adenine dinucleotide phosphate
	nicotinamide adenine dinucleophosphate reduced form
	nadide hydrogen phosphate
	beta nadph
	nicotine adenine dinucleotide phosphate
	nicotineamide-adenine dinucleotide phosphate
	NAD[P]H
	[4S-(2)H]NADPH
	53-57-6
	dihydrotriphosphopyridine nucleotide reduced
	beta reduced nicotinamide adenine dinucleotide phosphate
	beta-Nicotinamide-adenine-dinucleotide-phosphorate
	b-Nicotinamide-adenine-dinucleotide-phosphorate
	Dihydrocodehydrogenase II
	dihydronicotinamide adenine dinucleotide-P
	reduced Codehydrase II
	Adenosine 5'-(trihydrogen diphosphate), 2'-(dihydrogen phosphate), P'-5'-ester with 1,4-dihydro-1-beta-D-ribofuranosyl-3-pyridinecarboxamide
	EINECS 200-177-6
	NADP(H)
	NADPH
	Nicotinamide adenine dinucleotide phosphate
	nicotinamide adenine dinucleotide phosphate, reduced form
	Nicotinamide-adenine-dinucleotide-phosphorate
	Nicotinamide-adenine-dinucleotide-phosphoric acid
	Dihydronicotinamide-adenine dinucleotide phosphate
	NAD(P)H
	nicotinamide adenine dinucleotide phosphate (reduced form)
	nicotinamide adenine dinucleotide phosphate reduced
	22046-90-8
	3545-01-5

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KEGG ID	C00005

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MedScan ID	1081122

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HMDB ID	HMDB00221
	HMDB00799
	HMDB06341

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CAS ID	22046-90-8
	3545-01-5
	53-57-6

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PubChem SID	134971347
	148687

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PubChem CID	5884

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IUPAC Name	[[(2R,3R,4R,5R)-5-adenin-9-yl-3-hydroxy-4-phosphonooxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl] [(2R,3S,4R,5R)-5-(3-carbamoyl-4H-pyridin-1-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl hydrogen phosphate

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InChIKey	ACFIXJIJDZMPPO-NNYOXOHSSA-N

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Rotatable Bond Count	13

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Molecular Weight	745.420886
	745.420883

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Molecular Formula	C21H30N7O17P3

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XLogP	-6.800000
	-6.800000

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ChEBI ID	16474

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Reaxys ID	77911
	605068
	1208813
	1208814
	1208815
	1208816
	1208817

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LinkUrl	http://rgd.mcw.edu/rgdweb/ontology/view.html?acc_id=CHEBI:16474

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ChemIDplus ID	000053576

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