| URN | urn:agi-llid:3920 |
|---|---|
| Total Entities | 0 |
| Connectivity | 423 |
| Name | Lamp2 |
| Description | lysosomal-associated membrane protein 2 |
| Notes | The protein encoded by this gene is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands. It may play a role in tumor cell metastasis. It may also function in the protection, maintenance, and adhesion of the lysosome. Alternative splicing of this gene results in multiple transcript variants encoding distinct proteins. [provided by RefSeq, Jul 2008] |
| GO Cellular Component | membrane |
|---|---|
| integral component of membrane | |
| endosome membrane | |
| lysosomal membrane | |
| late endosome membrane | |
| platelet dense granule membrane | |
| phagocytic vesicle membrane | |
| plasma membrane | |
| endosome | |
| lysosome | |
| late endosome |
| GO Biological Process | blood coagulation |
|---|---|
| platelet activation | |
| platelet degranulation |
| Pathway | Transcytosis |
|---|---|
| Young Onset PARK2, PINK1, and UCHL1 Induced Parkinson's Disease | |
| Macrophage Function in Crohn's Disease | |
| chaperone mediated autophagy pathway |
| Group | ECM/Cell adhesion proteins |
|---|---|
| blood coagulation | |
| platelet activation | |
| platelet degranulation | |
| membrane | |
| integral component of membrane | |
| endosome membrane | |
| lysosomal membrane | |
| late endosome membrane | |
| platelet dense granule membrane | |
| phagocytic vesicle membrane | |
| plasma membrane | |
| endosome | |
| lysosome | |
| late endosome | |
| Genes with Mutations Associated with Hypertrophic Cardiomyopathy | |
| Biofluids assayable substances |
| LocusLink ID | 3920 |
|---|---|
| 16784 | |
| 24944 |
| Cell Localization | Extracellular |
|---|---|
| Cell membrane | |
| Endosome membrane | |
| Lysosome membrane |
| GO ID | 0007596 |
|---|---|
| 0030168 | |
| 0002576 | |
| 0016021 | |
| 0005770 | |
| 0031902 | |
| 0005765 | |
| 0005764 | |
| 0016020 | |
| 0030670 | |
| 0005886 | |
| 0031088 | |
| 0005768 | |
| 0010008 |
| Alias | LAMPB |
|---|---|
| CD107b | |
| LAMP-2 | |
| LGP110 | |
| lysosome-associated membrane glycoprotein 2 | |
| CD107 antigen-like family member B | |
| Mac3 | |
| Lamp-2a | |
| Lamp-2b | |
| Lamp-2c | |
| RP23-193O17.2 | |
| LGP-B | |
| Lamp II | |
| lysosomal membrane glycoprotein 2 | |
| lysosomal membrane glycoprotein type B | |
| lysosome-associated membrane protein 2 | |
| lysosome-associated membrane protein-2 | |
| LGP-96 | |
| LGP-110 | |
| OTTMUSP00000018739 | |
| Lysosome-associated membrane protein II | |
| LAMP 2 glycoprotein | |
| OTTHUMP00000023944 | |
| OTTMUSP00000018801 | |
| antigen CD107b | |
| CD107b antigen | |
| glycoprotein LAMP 2 | |
| Lysosomal-associated membrane protein II | |
| OTTHUMP00000023943 | |
| lysosomal membrane glycoprotein II | |
| Lysosomal-associated membrane protein 2 | |
| Lamp IIs | |
| LAMP2 | |
| lamp2a | |
| lamp2b |
| Mouse chromosome position | X 22.67 cM |
|---|
| OMIM ID | 309060 |
|---|---|
| 300257 |
| Rat chromosome position | Xq11 |
|---|
| Hugo ID | 6501 |
|---|
| Human chromosome position | Xq24 |
|---|
| Swiss-Prot Accession | P13473 |
|---|---|
| B7Z2R9 | |
| P17047 | |
| Q8C876 | |
| Q6P6W1 | |
| P17046 | |
| A8K4X5 | |
| D3DTF0 | |
| Q16641 | |
| Q6Q3G8 | |
| Q96J30 | |
| Q99534 | |
| Q9UD93 | |
| A2A430 | |
| Q3TXG5 | |
| Q8BSG8 |
| PIR ID | JC2414 |
|---|---|
| JC4317 | |
| A35560 |
| Unigene ID | Hs.496684 |
|---|---|
| Mm.486 | |
| Rn.1722 |
| KEGG ID | hsa:3920 |
|---|---|
| mmu:16784 | |
| rno:24944 |
| Swiss-Prot ID | LAMP2_HUMAN |
|---|---|
| LAMP2_MOUSE |
| Ensembl ID | ENSG00000005893 |
|---|---|
| ENSP00000360386 | |
| ENST00000371335 | |
| ENSMUSG00000016534 | |
| ENSMUSP00000016678 | |
| ENSMUST00000016678 | |
| ENSMUSP00000052283 | |
| ENSMUST00000061755 | |
| ENSMUSP00000074448 | |
| ENSMUST00000074913 | |
| ENSRNOG00000000164 | |
| ENSRNOP00000000177 | |
| ENSRNOT00000000177 |
| Homologene ID | 7809 |
|---|
| Organism | Homo sapiens |
|---|---|
| Mus musculus | |
| Rattus norvegicus |
| MGI ID | 96748 |
|---|
| RGD ID | 2990 |
|---|
| MedScan ID | 3920 |
|---|