| URN | urn:agi-llid:125170 |
|---|---|
| Total Entities | 0 |
| Connectivity | 11 |
| Name | Mief2 |
| Description | mitochondrial elongation factor 2 |
| Notes | This gene encodes an outer mitochondrial membrane protein that functions in the regulation of mitochondrial morphology. It can directly recruit the fission mediator dynamin-related protein 1 (Drp1) to the mitochondrial surface. The gene is located within the Smith-Magenis syndrome region on chromosome 17. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2011] |
| GO Cellular Component | membrane |
|---|---|
| integral component of membrane | |
| mitochondrial outer membrane | |
| mitochondrion | |
| peroxisome |
| GO Biological Process | mitochondrial fusion |
|---|---|
| positive regulation of protein targeting to membrane | |
| positive regulation of mitochondrial fission | |
| positive regulation of protein homooligomerization | |
| mitochondrion organization |
| Pathway | mitochondria dynamics pathway |
|---|
| Group | Transcription factors |
|---|---|
| mitochondrial fusion | |
| positive regulation of protein targeting to membrane | |
| positive regulation of mitochondrial fission | |
| positive regulation of protein homooligomerization | |
| mitochondrion organization | |
| membrane | |
| integral component of membrane | |
| mitochondrial outer membrane | |
| mitochondrion | |
| peroxisome |
| LocusLink ID | 125170 |
|---|---|
| 237781 | |
| 497916 |
| Cell Localization | Nucleus |
|---|---|
| Mitochondrion outer membrane |
| GO ID | 0008053 |
|---|---|
| 0007005 | |
| 0090141 | |
| 0032464 | |
| 0090314 | |
| 0016021 | |
| 0005741 | |
| 0005739 | |
| 0005777 | |
| 0016020 |
| Alias | MID49 |
|---|---|
| SMCR7 | |
| mitochondrial dynamic protein MID49 | |
| mitochondrial dynamic protein of 49 kDa | |
| Smith-Magenis syndrome chromosome region, candidate 7 | |
| Smith-Magenis syndrome chromosomal region candidate gene 7 protein | |
| Gm11 | |
| AI482195 | |
| mitochondrial dynamic protein of 49 kDa homolog | |
| smith-Magenis syndrome chromosomal region candidate gene 7 protein homolog | |
| RGD1560728 | |
| mitochondrial elongation factor 2 | |
| Smith-Magenis syndrome chromosome region, candidate 7 homolog | |
| OTTMUSP00000008171 | |
| Smith-Magenis syndrome chromosome region, candidate VII | |
| Smith-Magenis syndrome chromosome region, candidate 7 homolog (human) | |
| Mief2 | |
| LOC194946 | |
| Smith-Magenis syndrome chromosome region, candidate | |
| MGC113770 | |
| MGC23130 |
| Mouse chromosome position | 11 |
|---|
| OMIM ID | 615498 |
|---|
| Rat chromosome position | 10q22 |
|---|
| Hugo ID | 17920 |
|---|
| Human chromosome position | 17p11.2 |
|---|
| Swiss-Prot Accession | Q96C03 |
|---|---|
| Q5NCS9 | |
| D3ZS35 | |
| J3KPT3 | |
| Q6ZRD4 | |
| Q96N07 |
| Unigene ID | Hs.655555 |
|---|---|
| Mm.339760 |
| KEGG ID | hsa:125170 |
|---|---|
| mmu:237781 | |
| rno:497916 |
| Swiss-Prot ID | MID49_HUMAN |
|---|---|
| MID49_MOUSE |
| Ensembl ID | ENSG00000177427 |
|---|---|
| ENSP00000379056 | |
| ENST00000395704 | |
| ENSP00000379057 | |
| ENST00000395706 | |
| ENSMUSG00000018599 | |
| ENSMUSP00000018743 | |
| ENSMUST00000018743 |
| Homologene ID | 27354 |
|---|
| Organism | Homo sapiens |
|---|---|
| Mus musculus | |
| Rattus norvegicus |
| MGI ID | 2144199 |
|---|
| RGD ID | 1560728 |
|---|
| MedScan ID | 125170 |
|---|