| URN | urn:agi-llid:9751 |
|---|---|
| Total Entities | 0 |
| Connectivity | 39 |
| Name | Snph |
| Description | syntaphilin |
| Notes | Syntaxin-1, synaptobrevin/VAMP, and SNAP25 interact to form the SNARE complex, which is required for synaptic vesicle docking and fusion. The protein encoded by this gene is membrane-associated and inhibits SNARE complex formation by binding free syntaxin-1. Expression of this gene appears to be brain-specific. [provided by RefSeq, Jul 2008] |
| GO Molecular Function | syntaxin-1 binding |
|---|
| GO Cellular Component | membrane |
|---|---|
| synapse | |
| cell junction | |
| integral component of membrane | |
| presynaptic membrane | |
| mitochondrial membrane | |
| cytoplasmic microtubule | |
| plasma membrane | |
| mitochondrion | |
| neuron projection | |
| neuronal cell body |
| GO Biological Process | brain development |
|---|---|
| neuron differentiation | |
| vesicle fusion | |
| neurotransmitter secretion | |
| synaptic vesicle docking involved in exocytosis | |
| negative regulation of endocytosis |
| Pathway | Exocytosis |
|---|---|
| mitochondria dynamics pathway |
| Group | brain development |
|---|---|
| neuron differentiation | |
| vesicle fusion | |
| neurotransmitter secretion | |
| synaptic vesicle docking involved in exocytosis | |
| negative regulation of endocytosis | |
| syntaxin-1 binding | |
| membrane | |
| synapse | |
| cell junction | |
| integral component of membrane | |
| presynaptic membrane | |
| mitochondrial membrane | |
| cytoplasmic microtubule | |
| plasma membrane | |
| mitochondrion | |
| neuron projection | |
| neuronal cell body |
| LocusLink ID | 9751 |
|---|---|
| 241727 | |
| 296267 |
| Cell Localization | Membrane |
|---|---|
| Cell junction | |
| Synapse | |
| Synaptosome |
| GO ID | 0017075 |
|---|---|
| 0007420 | |
| 0030182 | |
| 0007269 | |
| 0016081 | |
| 0030054 | |
| 0005881 | |
| 0016021 | |
| 0031966 | |
| 0043005 | |
| 0043025 | |
| 0042734 | |
| 0045806 | |
| 0006906 | |
| 0016020 | |
| 0005739 | |
| 0005886 | |
| 0045202 |
| Alias | bA314N13.5 |
|---|---|
| syntaphilin | |
| AW045671 | |
| AW556958 | |
| AW743098 | |
| mKIAA0374 | |
| 6430515A01 | |
| RP23-419G21.8 | |
| KIAA0374 | |
| OTTHUMP00000070985 | |
| OTTHUMP00000029965 | |
| SNPH | |
| OTTMUSP00000015707 | |
| OTTMUSP00000015703 | |
| MGC46096 | |
| OTTMUSP00000015704 |
| Mouse chromosome position | 2 |
|---|
| OMIM ID | 604942 |
|---|
| Rat chromosome position | 3q41 |
|---|
| Hugo ID | 15931 |
|---|
| Human chromosome position | 20p13 |
|---|
| Swiss-Prot Accession | O15079 |
|---|---|
| Q80U23 | |
| B5DF41 | |
| Q8IYI3 | |
| A2AT08 | |
| A2AT09 | |
| A2AT10 | |
| A2AT11 | |
| A4FUV3 | |
| A4VCI7 | |
| Q4VA51 | |
| Q6GQX4 | |
| Q8C8B8 |
| Unigene ID | Hs.323833 |
|---|---|
| Mm.39312 | |
| Rn.234551 |
| KEGG ID | hsa:9751 |
|---|---|
| mmu:241727 | |
| rno:296267 |
| Swiss-Prot ID | SNPH_HUMAN |
|---|---|
| SNPH_MOUSE | |
| SNPH_RAT |
| Ensembl ID | ENSG00000101298 |
|---|---|
| ENSP00000371297 | |
| ENST00000381873 | |
| ENSP00000371291 | |
| ENST00000381867 | |
| ENSMUSG00000027457 | |
| ENSMUSP00000028951 | |
| ENSMUST00000028951 | |
| ENSMUSP00000092026 | |
| ENSMUST00000094456 |
| Homologene ID | 8817 |
|---|
| Organism | Homo sapiens |
|---|---|
| Mus musculus | |
| Rattus norvegicus |
| MGI ID | 2139270 |
|---|
| RGD ID | 1305867 |
|---|
| MedScan ID | 9751 |
|---|