| URN | urn:agi-llid:55669 |
|---|---|
| Total Entities | 0 |
| Connectivity | 174 |
| Name | Mfn1 |
| Description | mitofusin 1 |
| Notes | The protein encoded by this gene is a mediator of mitochondrial fusion. This protein and mitofusin 2 are homologs of the Drosophila protein fuzzy onion (Fzo). They are mitochondrial membrane proteins that interact with each other to facilitate mitochondrial targeting. [provided by RefSeq, Jul 2008] |
| GO Molecular Function | GTPase activity |
|---|---|
| hydrolase activity | |
| nucleotide binding | |
| GTP binding |
| GO Cellular Component | membrane |
|---|---|
| integral component of membrane | |
| mitochondrial outer membrane | |
| mitochondrion |
| GO Biological Process | GTP catabolic process |
|---|---|
| multicellular organismal development | |
| mitochondrial fusion |
| Pathway | Mitochondrial Fusion and Fission |
|---|---|
| mitochondria dynamics pathway |
| Group | GTP catabolic process |
|---|---|
| GTPase activity | |
| multicellular organismal development | |
| mitochondrial fusion | |
| hydrolase activity | |
| nucleotide binding | |
| GTP binding | |
| membrane | |
| integral component of membrane | |
| mitochondrial outer membrane | |
| mitochondrion |
| LocusLink ID | 55669 |
|---|---|
| 67414 | |
| 192647 |
| Cell Localization | Mitochondrion outer membrane |
|---|---|
| Cytoplasm |
| GO ID | 0005525 |
|---|---|
| 0003924 | |
| 0008053 | |
| 0016021 | |
| 0005741 | |
| 0016787 | |
| 0000166 | |
| 0006184 | |
| 0007275 | |
| 0016020 | |
| 0005739 |
| Alias | hfzo1 |
|---|---|
| hfzo2 | |
| mitofusin-1 | |
| fzo homolog | |
| transmembrane GTPase MFN1 | |
| putative transmembrane GTPase | |
| mitochondrial transmembrane GTPase FZO-2 | |
| mitochondrial transmembrane GTPase Fzo-1 | |
| HR2 | |
| mKIAA4032 | |
| D3Ertd265e | |
| 2310002F04Rik | |
| 6330416C07Rik | |
| Fzo1b | |
| mitochondrial transmembrane GTPase FZO1B | |
| MGC41806 | |
| mitofusin 1 | |
| mitofusin I | |
| RIKEN cDNA 2310002F04 gene | |
| OTTHUMP00000212066 | |
| OTTMUSP00000035188 | |
| MFN1 | |
| OTTHUMP00000212067 | |
| DKFZp762f247 | |
| MFN I | |
| 2310002F04 | |
| 6330416C07 | |
| DNA segment, Chr 3, ERATO Doi 265, expressed | |
| KIAA4032 | |
| LOC229181 | |
| LOC113736 |
| Mouse chromosome position | 3 15.75 cM |
|---|
| OMIM ID | 608506 |
|---|
| Rat chromosome position | 2q25 |
|---|
| Hugo ID | 18262 |
|---|
| Human chromosome position | 3q26.33 |
|---|
| Swiss-Prot Accession | Q8IWA4 |
|---|---|
| Q811U4 | |
| Q8R4Z9 | |
| Q3URC4 | |
| Q811D5 | |
| Q8CEY6 | |
| Q99M10 | |
| Q9D395 | |
| B2RAR1 | |
| D3DNR6 | |
| O15323 | |
| O60639 | |
| Q9BZB5 | |
| Q9NWQ2 |
| Unigene ID | Hs.478383 |
|---|---|
| Mm.290414 | |
| Rn.160939 |
| KEGG ID | hsa:55669 |
|---|---|
| mmu:67414 | |
| rno:192647 |
| Swiss-Prot ID | MFN1_MOUSE |
|---|---|
| MFN1_RAT | |
| MFN1_HUMAN |
| EC Number | 3.6.5.- |
|---|
| Ensembl ID | ENSG00000171109 |
|---|---|
| ENSP00000280653 | |
| ENST00000280653 | |
| ENSMUSG00000027668 | |
| ENSMUSP00000088801 | |
| ENSMUST00000091257 | |
| ENSRNOG00000011057 | |
| ENSRNOP00000060265 | |
| ENSRNOT00000065144 |
| Homologene ID | 11481 |
|---|
| Organism | Homo sapiens |
|---|---|
| Mus musculus | |
| Rattus norvegicus |
| MGI ID | 1914664 |
|---|
| RGD ID | 621460 |
|---|
| MedScan ID | 55669 |
|---|