| URN | urn:agi-llid:8199 |
|---|---|
| Total Entities | 0 |
| Connectivity | 62 |
| Name | Map1lc3a |
| Description | microtubule-associated protein 1 light chain 3 alpha |
| Notes | MAP1A and MAP1B are microtubule-associated proteins which mediate the physical interactions between microtubules and components of the cytoskeleton. MAP1A and MAP1B each consist of a heavy chain subunit and multiple light chain subunits. The protein encoded by this gene is one of the light chain subunits and can associate with either MAP1A or MAP1B. Two transcript variants encoding different isoforms have been found for this gene. The expression of variant 1 is suppressed in many tumor cell lines, suggesting that may be involved in carcinogenesis. [provided by RefSeq, Feb 2012] |
| GO Molecular Function | microtubule binding |
|---|---|
| phospholipid binding | |
| phosphatidylethanolamine binding |
| GO Cellular Component | membrane |
|---|---|
| organelle membrane | |
| autophagic vacuole membrane | |
| microtubule | |
| endomembrane system | |
| cytoplasm | |
| cytosol | |
| cytoplasmic vesicle | |
| autophagic vacuole | |
| late endosome | |
| cytoskeleton |
| GO Biological Process | autophagic vacuole assembly |
|---|---|
| autophagy | |
| mitochondrion degradation |
| Pathway | mitochondrial autophagy pathway |
|---|
| Group | Microtubule cytoskeleton assembly |
|---|---|
| autophagic vacuole assembly | |
| autophagy | |
| mitochondrion degradation | |
| microtubule binding | |
| phospholipid binding | |
| phosphatidylethanolamine binding | |
| membrane | |
| organelle membrane | |
| autophagic vacuole membrane | |
| microtubule | |
| endomembrane system | |
| cytoplasm | |
| cytosol | |
| cytoplasmic vesicle | |
| autophagic vacuole | |
| late endosome | |
| cytoskeleton | |
| Secreted proteins |
| LocusLink ID | 8199 |
|---|---|
| 84557 | |
| 66734 | |
| 362245 |
| Cell Localization | Cytoplasm |
|---|---|
| Cytoskeleton | |
| Endomembrane system | |
| Cytoplasmic vesicle | |
| Autophagosome membrane |
| GO ID | 0008429 |
|---|---|
| 0005543 | |
| 0000045 | |
| 0000422 | |
| 0005776 | |
| 0000421 | |
| 0031410 | |
| 0005829 | |
| 0012505 | |
| 0005770 | |
| 0005874 | |
| 0031090 | |
| 0008017 | |
| 0006914 | |
| 0005737 | |
| 0005856 | |
| 0016020 |
| Alias | LC3 |
|---|---|
| LC3A | |
| ATG8E | |
| MAP1ALC3 | |
| MAP1BLC3 | |
| RP11-346K17.1 | |
| microtubule-associated proteins 1A/1B light chain 3A | |
| MAP1A/MAP1B LC3 A | |
| MAP1A/1B light chain 3 A | |
| MAP1A/MAP1B light chain 3 A | |
| MAP1 light chain 3-like protein 1 | |
| autophagy-related ubiquitin-like modifier LC3 A | |
| microtubule-associated proteins 1A/1B light chain 3 | |
| 1010001H21Rik | |
| 4922501H04Rik | |
| RP23-87L24.4 | |
| autophagy-related protein LC3 A | |
| microtubule-associated proteins 1A/1B light chain III | |
| MAP1LC3A | |
| MGC105263 | |
| microtubule-associated protein 1 light chain 3 alpha | |
| OTTHUMP00000030696 | |
| OTTHUMP00000030697 | |
| OTTHUMP00000030698 | |
| OTTMUSP00000017090 | |
| RIKEN cDNA 1010001H21 gene | |
| 1010001H21 | |
| 4922501H04 | |
| MAP1 light chain 3-like protein I |
| Mouse chromosome position | 2 |
|---|
| OMIM ID | 601242 |
|---|
| Rat chromosome position | 3q42 |
|---|
| Hugo ID | 6838 |
|---|
| Human chromosome position | 20q11.22 |
|---|
| Swiss-Prot Accession | Q9H492 |
|---|---|
| Q91VR7 | |
| Q6XVN8 | |
| A2AVS1 | |
| Q9DC74 | |
| E1P5P4 | |
| E1P5P5 | |
| Q9BXW5 |
| Unigene ID | Hs.632273 |
|---|---|
| Mm.196239 | |
| Rn.3135 |
| KEGG ID | hsa:84557 |
|---|---|
| mmu:66734 | |
| rno:362245 |
| Swiss-Prot ID | MLP3A_RAT |
|---|---|
| MLP3A_MOUSE | |
| MLP3A_HUMAN |
| Ensembl ID | ENSG00000101460 |
|---|---|
| ENSP00000363970 | |
| ENST00000374837 | |
| ENSP00000353886 | |
| ENST00000360668 | |
| ENSMUSG00000027602 | |
| ENSMUSP00000029128 | |
| ENSMUST00000029128 | |
| ENSRNOG00000025443 | |
| ENSRNOP00000032429 | |
| ENSRNOT00000035060 |
| Homologene ID | 12021 |
|---|
| Organism | Homo sapiens |
|---|---|
| Mus musculus | |
| Rattus norvegicus |
| MGI ID | 1915661 |
|---|
| RGD ID | 735183 |
|---|
| MedScan ID | 8199 |
|---|