| URN | urn:agi-llid:6714 |
|---|---|
| Total Entities | 0 |
| Connectivity | 4769 |
| Name | Src |
| Description | Rous sarcoma oncogene |
| Notes | mediates growth effects of both the precursor and fully processed forms of gastrins on rat intestinal epithelial cells [RGD] |
| GO Molecular Function | SH3-SH2 adaptor activity |
|---|---|
| transferase activity | |
| transferase activity, transferring phosphorus-containing groups | |
| kinase activity | |
| protein kinase activity | |
| protein tyrosine kinase activity | |
| non-membrane spanning protein tyrosine kinase activity | |
| protein complex binding | |
| phosphoprotein binding | |
| ion channel binding | |
| protein domain specific binding | |
| protein C-terminus binding | |
| cell adhesion molecule binding | |
| enzyme binding | |
| receptor binding | |
| integrin binding | |
| insulin receptor binding | |
| growth factor receptor binding | |
| ephrin receptor binding | |
| estrogen receptor binding | |
| protein kinase binding | |
| protein kinase C binding | |
| SH2 domain binding | |
| nucleotide binding | |
| ATP binding | |
| heme binding |
| GO Cellular Component | membrane |
|---|---|
| caveola | |
| mitochondrial inner membrane | |
| postsynaptic density | |
| plasma membrane | |
| cytoplasm | |
| cytosol | |
| mitochondrion | |
| lysosome | |
| late endosome | |
| cytoskeleton | |
| nucleus | |
| neuron projection |
| GO Biological Process | immune system process |
|---|---|
| oogenesis | |
| uterus development | |
| leukocyte migration | |
| Fc-gamma receptor signaling pathway involved in phagocytosis | |
| innate immune response | |
| T cell costimulation | |
| cell proliferation | |
| positive regulation of MAP kinase activity | |
| positive regulation of ERK1 and ERK2 cascade | |
| positive regulation of glucose metabolic process | |
| positive regulation of phosphatidylinositol 3-kinase activity | |
| bone resorption | |
| regulation of bone resorption | |
| branching involved in mammary gland duct morphogenesis | |
| positive regulation of cytokine secretion | |
| blood coagulation | |
| platelet activation | |
| regulation of vascular permeability | |
| forebrain development | |
| axon guidance | |
| cell cycle | |
| cell adhesion | |
| positive regulation of cyclin-dependent protein kinase activity | |
| signal transduction | |
| intracellular signal transduction | |
| positive regulation of intracellular signal transduction | |
| Ras protein signal transduction | |
| negative regulation of intrinsic apoptotic signaling pathway | |
| positive regulation of protein kinase B signaling | |
| negative regulation of extrinsic apoptotic signaling pathway | |
| positive regulation of insulin receptor signaling pathway | |
| positive regulation of platelet-derived growth factor receptor signaling pathway | |
| positive regulation of canonical Wnt signaling pathway | |
| signal complex assembly | |
| regulation of intracellular estrogen receptor signaling pathway | |
| progesterone receptor signaling pathway | |
| neurotrophin TRK receptor signaling pathway | |
| fibroblast growth factor receptor signaling pathway | |
| epidermal growth factor receptor signaling pathway | |
| cell-cell adhesion | |
| positive regulation of cell adhesion | |
| negative regulation of focal adhesion assembly | |
| cell migration | |
| positive regulation of smooth muscle cell migration | |
| positive regulation of apoptotic process | |
| negative regulation of apoptotic process | |
| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process | |
| negative regulation of anoikis | |
| adherens junction organization | |
| transcytosis | |
| response to drug | |
| response to fatty acid | |
| response to hydrogen peroxide | |
| cellular response to insulin stimulus | |
| cellular response to lipopolysaccharide | |
| cellular response to progesterone stimulus | |
| cellular response to fatty acid | |
| cellular response to hypoxia | |
| response to mineralocorticoid | |
| response to interleukin-1 | |
| response to mechanical stimulus | |
| response to virus | |
| response to nutrient levels | |
| response to electrical stimulus | |
| response to acidity | |
| positive regulation of DNA biosynthetic process | |
| positive regulation of transcription, DNA-templated | |
| positive regulation of protein autophosphorylation | |
| activation of protein kinase B activity | |
| positive regulation of gene expression | |
| positive regulation of podosome assembly | |
| positive regulation of integrin activation | |
| positive regulation of protein transport | |
| negative regulation of protein homooligomerization | |
| negative regulation of transcription, DNA-templated | |
| negative regulation of mitochondrial depolarization | |
| protein phosphorylation | |
| peptidyl-serine phosphorylation | |
| peptidyl-tyrosine phosphorylation | |
| protein autophosphorylation | |
| phosphorylation | |
| modulation by virus of host morphology or physiology | |
| regulation of protein binding |
| Pathway | Focal Junction Assembly |
|---|---|
| Adherens Junction Assembly (Cadherins) | |
| Adherens Junction Assembly (Nectin) | |
| Androgen Receptor Coregulator ARA55 (TGFB1I1) in Prostate Cancer | |
| Prostate Cancer Overview | |
| Metastatic Colorectal Cancer Overview | |
| Dystrophin Glycoprotein Complex Signaling in Duchenne Muscular Dystrophy | |
| Ca2+ Overload in Duchenne Muscular Dystrophy | |
| Duchenne Muscular Dystrophy Overview | |
| Proteins Involved in Pathogenesis of Alzheimer's Disease | |
| IL-6/IGF-1/VEGFA in Multiple Myeloma | |
| Osteoclast Activation in Multiple Myeloma | |
| Multiple Myeloma Overview | |
| Proteins Involved in Pathogenesis of Chronic Myeloid Leukemia | |
| Chronic Myeloid Leukemia Overview | |
| B-cell Acute Lymphoblastic Leukemia Overview | |
| B-cell Chronic Lymphocytic Leukemia Overview | |
| Hodgkin Lymphoma Overview | |
| Follicular Lymphoma Overview | |
| Cowden Syndrome | |
| Mucosa-Associated Lymphoid Tissue (MALT) Lymphoma Overview | |
| Proteins Involved in Pathogenesis of Breast Cancer Related to ERBB2/VEGFR/Akt Signaling Pathway | |
| Proteins Involved in Pathogenesis of Breast Cancer Related to IGF1R/Akt Signaling Pathway | |
| Breast Cancer Related to IGF1R/Akt Signaling Pathway | |
| Breast Cancer Related to ERBB/VEGFR/Akt Signaling Pathway | |
| Breast Cancer Related to ESR1 Signaling Pathway | |
| Proteins Involved in Pathogenesis of Breast Cancer Related to ESR1 Signaling Pathway | |
| ESR1/ERBB-positive Luminal Breast Cancer | |
| Basal Breast Cancer | |
| Proliferative Diabetic Retinopathy | |
| Common Non-genomic Effects of Thyroid Hormones | |
| Effects of Hyperthyroidism on Bone Remodeling | |
| Clear Cell Ovarian Carcinoma | |
| Proteins Involved in Pathogenesis of Clear Cell Ovarian Carcinoma | |
| Mucinous Ovarian Carcinoma | |
| High-grade Serous Ovarian Carcinoma | |
| Proteins Involved in Pathogenesis of Mucinous Ovarian Carcinoma | |
| Proteins Involved in Pathogenesis of High-grade Serous Ovarian Carcinoma | |
| Endometrioid Ovarian Carcinoma | |
| Proteins Involved in Pathogenesis of Endometrioid Ovarian Carcinoma | |
| Ovarian Cancer Overview | |
| Low-grade Serous Ovarian Carcinoma | |
| Proteins Involved in Pathogenesis of Low-grade Serous Ovarian Carcinoma | |
| Type I Endometrial Cancer (Endometrioid Endometrial Cancer) | |
| Type II Endometrial Cancer (Clear-cell Endometrial Cancer and Papillary Serous Endometrial Cancer) | |
| Endometrial Cancer Overview | |
| Proteins Involved in Pathogenesis of Melanoma | |
| Melanoma Overview | |
| Proteins Involved in Pathogenesis of Prostate Cancer | |
| Cancer Overview | |
| Endothelial Cell Dysfunction in Pulmonary Arterial Hypertension | |
| Proteins Involved in Pathogenesis of Pulmonary Hypertension | |
| Primary Glioblastoma | |
| Medulloblastoma Overview | |
| CCR5 Signaling in Macrophages in HIV Type 1 Infection | |
| Macrophage Survival through CCR5 and CXCR4 Mediated Signaling in HIV Type 1 Infection | |
| Ca2+ Toxicity in Lens Cells | |
| Proteins Involved in Pathogenesis of Cataract | |
| Growth Factor Signaling in Neuroblastoma | |
| Proteins Involved in Pathogenesis of Neuroblastoma | |
| Neuroblastoma Overview | |
| Growth Factor Signaling in Pancreatic Cancer | |
| Pancreatic Ductal Carcinoma | |
| Proteins Involved in Pathogenesis of Pancreatic Cancer | |
| Pancreatic Neuroendocrine Tumors | |
| Growth Factor Signaling in Hepatocellular Carcinoma | |
| Proteins Involved in Pathogenesis of Hepatocellular Carcinoma | |
| Hepatocellular Carcinoma Overview | |
| Osteoclast Activation in Gout | |
| Impairment of Microglia Inhibition by Motor Neuron in Amyotrophic Lateral Sclerosis | |
| Synovial Fibroblast Proliferation in Rheumatoid Arthritis | |
| Osteoclast Activation in Rheumatoid Arthritis | |
| Proteins Involved in Pathogenesis of Epilepsy | |
| Effects of BDNF Upregulation Induced by Seizures | |
| Role of HMGB1 and IL1B in Neuronal Hyperexcitation in Epilepsy | |
| Regulation of Vascular Reactivity in Raynaud Disease | |
| Model Autocrine Cytokine/Chemokine Loops in Systemic Scleroderma Fibroblasts 1 | |
| Mechanism of Skin Fibrosis in Systemic Scleroderma | |
| Myocardial Remodeling in Myocardial Ischemia | |
| WHIM Syndrom Overview | |
| ADRA2C/ADRB2 -> vasoconstriction | |
| ADRB1 -> prostaglandin generation | |
| ADRA2C/ADRB2 -> synaptic endocytosis | |
| GABA(B)R -> postsynaptic inhibition | |
| DRD2 -> TRPC1 transcription | |
| DRD2/4 -> membrane transport | |
| Nociception-related DRD2 expression targets | |
| CHRM1 -> IL2 production | |
| EPHB -> NMDA receptor activation | |
| NTRK1/2/3 -> acetylcholine production | |
| Nociception-related IL6 expression targets | |
| GFs/TNF -> ion channels | |
| Regulation of potassium flux | |
| Summarized nociception-related expression targets | |
| Summarized vascular motility pathway | |
| Regulation of calcium flux | |
| OPRK -> pain perception | |
| FGFR -> AP-1/CREB/CREBBP/ELK-SRF/MYC signaling | |
| PDGFR -> AP-1/MYC signaling | |
| VEGFR -> AP-1/CREB/MYC signaling | |
| HGFR -> AP-1/CREB/MYC signaling | |
| AngiopoietinR -> AP-1 signaling | |
| ErythropoietinR -> AP-1/CREB/MYC signaling | |
| ThrombopoietinR -> AP-1/CREB/ELK-SRF/MYC signaling | |
| EGFR -> AP-1/CREB/ELK-SRF/MYC signaling | |
| EGFR -> NCOR2 signaling | |
| TNFRSF5/13B -> NFATC1 signaling | |
| T-cell receptor -> ATF/CREB signaling | |
| EGFR/ERBB2 -> HIF1A signaling | |
| EGFR -> AP-1/ATF2 signaling | |
| EGFR/ERBB2 -> TP53 signaling | |
| EGFR -> CTNND signaling | |
| EGFR/ERBB3 -> MEF/MYOD/NFATC/MYOG signaling | |
| EGFR/ERBB2 -> CTNNB signaling | |
| EGFR/ERBB -> STAT signaling | |
| FGFR1 -> STAT signaling | |
| KIT -> MITF signaling | |
| PDGFR -> STAT signaling | |
| CSF1R -> STAT signaling | |
| VEGFR -> CTNNB signaling | |
| VEGFR -> NFATC signaling | |
| VEGFR -> ATF/CREB/ELK-SRF signaling | |
| VEGFR -> CTNND signaling | |
| VEGFR -> STAT signaling | |
| HGFR -> STAT signaling | |
| IGF1R -> ELK-SRF/HIF1A/MYC/SREBF signaling | |
| IGF1R -> MEF/MYOD/MYOG signaling | |
| GDNF -> HSF1 signaling | |
| NTRK -> FOXO/MYCN signaling | |
| NTRK -> AP-1/CREB/ELK-SRF/MYC/SMAD3/TP53 signaling | |
| MacrophageR -> CEBPB/NF-kB signaling | |
| PECAM -> STAT signaling | |
| FibronectinR -> AP-1/ELK-SRF/SREBF signaling | |
| IL6ST -> STAT5B signaling | |
| CholinergicRm -> CREB/ELK-SRF signaling | |
| DopamineR2 -> AP-1/CREB/ELK-SRF signaling | |
| DopamineR2 -> NF-kB signaling | |
| VasopressinR1 -> MEF/MYOD/NFATC/MYOG signaling | |
| VasopressinR1 -> STAT signaling | |
| AdenosineR -> NF-kB signaling | |
| VasopressinR1 -> CREB/ELK-SRF/AP-1/EGR signaling | |
| OpioidR -> CREB/ELK-SRF/STAT3 signaling | |
| GRM1/5 -> CREB signaling | |
| AdrenergicRb -> CREB signaling | |
| AdrenergicRb -> STAT3 signaling | |
| VasopressinR2 -> STAT signaling | |
| VasopressinR2 -> CREB/ELK-SRF/AP-1/EGR signaling | |
| VasopressinR2 -> MEF/MYOD/NFATC/MYOG signaling | |
| ThrombinR -> STAT1 signaling | |
| ThrombinR -> NF-kB signaling | |
| ThrombinR -> AP-1/CREB/ELK-SRF/SP1 signaling | |
| ROS in Angiotensin-Mediated Cardiovascular Remodeling and Hypertrophy | |
| NGF/FOXO/MYCN/ELK-SRF Expression Targets | |
| BDNF Expression Targets | |
| CD40LG/NF-kB/ELK-SRF/CREB/NFATC Expression Targets | |
| TNFSF13B Expression Targets | |
| NGF/AP-1/TP53/MYC Expression Targets | |
| NGF/CREB/CEBPB/MEF2A Expression Targets | |
| NGF/SMAD3/NF-kB Expression Targets | |
| ICAM1 Expression Targets | |
| Fibrinogen Expression Targets | |
| IL6 Expression Targets | |
| Dopamine/Gi Expression Targets | |
| Acetylcholine Expression Targets | |
| AREG/STAT Expression Targets | |
| AREG/AP-1 Expression Targets | |
| AREG/HIF1A Expression Targets | |
| AREG/NFATC Expression Target | |
| BTC/STAT Expression Targets | |
| BTC/NFATC Expression Targets | |
| EGF/HIF1A Expression Targets | |
| EGF/TP53 Expression Targets | |
| EREG/CTNNB/CTNND Expression Target | |
| EREG/STAT Expression Targets | |
| EREG/AP-1/ATF Expression Targets | |
| EREG/HIF1A Expression Target | |
| HBEGF/STAT Expression Targets | |
| HBEGF/AP-1/ATF Expression Targets | |
| HBEGF/HIF1A Expression Targets | |
| HBEGF/MEF/MYOD Expression Target | |
| HBEGF/TP53 Expression Targets | |
| NRG1/Catenin Expression Targets | |
| NRG1/STAT Expression Targets | |
| NRG1/AP-1/ATF Expression Targets | |
| NRG1/HIF1A Expression Target | |
| NRG1/MEF/MYOD Expression Targets | |
| NRG1/TP53 Expression Target | |
| TGFA/CTNNB/CTNND Expression Targets | |
| TGFA/STAT Expression Targets | |
| TGFA/HIF1A Expression Targets | |
| TGFA/MEF/MYOD/NFATC Expression Targets | |
| TGFA/TP53 Expression Targets | |
| FGF1/STAT Expression Targets | |
| FGF10/STAT Expression Targets | |
| CSF1/STAT Expression Targets | |
| PDGFB/STAT Expression Target | |
| PDGFC/STAT Expression Target | |
| PDGFD/STAT Expression Targets | |
| VEGFA/CTNNB/CTNND Expression Targets | |
| VEGFA/NFATC Expression Targets | |
| VEGFA/ATF/CREB/ELK-SRF Expression Targets | |
| VEGFC/CTNNB Expression Target | |
| VEGFC/ATF Expression Target | |
| GDNF/HSF1 Expression Targets | |
| IGF2/MEF/MYOD Expression Targets | |
| IGF2/HIF1A/MYC Expression Targets | |
| CTGF/AP-1/CREB/MYC Expression Targets | |
| CTGF/NCOR2 Expression Target | |
| Erythropoietin/AP-1/MYC/CREB Expression Targets | |
| FLT3LG/AP-1/CREB/CREBBP Expression Targets | |
| GAS6/AP-1/CREB Expression Targets | |
| PGF/AP-1/CREB/CREBBP/MYC Expression Targets | |
| Thrombopoietin/AP-1/CREB/CREBBP/MYC Expression Targets | |
| AREG/CREB/CREBBP Expression Targets | |
| AREG/NCOR2 Expression Targets | |
| EGF/NCOR2 Expression Target | |
| EREG/CREB Expression Target | |
| HBEGF/CREB/MYC Expression Targets | |
| NRG1/CREB/CREBBP/ELK-SRF/MYC Expression Targets | |
| TGFA/CREB/CREBBP/ELK-SRF/MYC Expression Targets | |
| FGF1/AP-1/CREB/ELK-SRF/MYC Expression Targets | |
| FGF1/NCOR2 Expression Target | |
| FGF2/NCOR2 Expression Targets | |
| FGF4/AP-1/MYC Expression Targets | |
| FGF7/AP-1/CREB/CREBBP/MYC Expression Targets | |
| FGF8/AP-1/CREB/MYC Expression Targets | |
| FGF9/AP-1/CREB/MYC Expression Targets | |
| FGF10/AP-1/CREB/CREBBP/MYC Expression Targets | |
| FGF18/AP-1/CREB Expression Targets | |
| FGF23/NCOR2 Expression Targets | |
| CSF1/AP-1/CREB/CREBBP/MYC Expression Targets | |
| PDGFB/AP-1/CREB/MYC Expression Target | |
| PDGFC/CREB Expression Target | |
| PDGFD/AP-1 Expression Targets | |
| VEGFA/NCOR2 Expression Target | |
| ANGPT1/CREB/CREBBP Expression Targets | |
| ANGPT2/AP-1/CREBBP/MYC Expression Targets | |
| FIGF/AP-1 Expression Target | |
| FIGF/NCOR2 Expression Target | |
| F2 -> AP-1/CREB/ELK-SRF/SP1 Expression Targets | |
| F2 -> STAT1/NF-kB Expression Targets | |
| PLG -> AP-1/CREB/ELK-SRF/SP1 Expression Targets | |
| PLG -> STAT1/NF-kB Expression Targets | |
| Adenosine Expression Targets | |
| Glutamate/Gq Expression Targets | |
| AVP/Gq -> STAT Expression Targets | |
| AVP/Gq -> MEF/MYOD/NFATC/MYOG Expression Targets | |
| AVP/Gq -> CREB/ELK-SRF/AP-1/EGR Expression Targets | |
| Morphine Expression Targets | |
| Epinephrine/Gs Expression Targets | |
| Noradrenaline/Gs Expression Targets | |
| AVP/Gs -> STAT Expression Targets | |
| AVP/Gs -> MEF/MYOD/NFATC/MYOG Expression Targets | |
| AVP/Gs -> CREB/ELK-SRF/AP-1/EGR Expression Targets | |
| POMC Expression Targets | |
| IFNA1/Gq Expression Targets | |
| IL16/ATF/CREB/CREBBP Expression Target | |
| CD8/ATF/CREB/CREBBP Expression Targets | |
| CD80/ATF/CREB/CREBBP Expression Targets | |
| CD86/ATF/CREB/CREBBP Expression Targets | |
| CD72/CREB/CREBBP Expression Targets | |
| PDCD1/ATF/CREB/CREBBP Expression Targets | |
| TCR/AP-1 Expression Targets | |
| TCR/CREB/CREBBP/ATF Expression Targets | |
| FGF2/AP-1/CREB/CREBBP/ELK-SRF/MYC Expression Targets | |
| HGF/STAT Expression Targets | |
| Insulin/ELK-SRF/HIF1A/MYC/SREBF Expression Targets | |
| VEGFA/STAT Expression Targets | |
| FGF2/STAT Expression Targets | |
| WNT5A Expression Targets | |
| EGF/AP-1/ATF Expression Targets | |
| EGF/CREB/CREBBP/ELK-SRF/MYC Expression Targets | |
| EGF/MEF/MYOD/NFATC Expression Targets | |
| EGF/STAT Expression Targets | |
| HGF/AP-1/CREB/ELK-SRF/MYC Expression Targets | |
| IGF1/ELK-SRF/HIF1A/MYC/SREBF Expression Targets | |
| IGF1/MEF/MYOD/MYOG Expression Targets | |
| Insulin/MEF/MYOD Expression Targets | |
| KITLG/AP-1/CREB/CREBBP/MYC Expression Targets | |
| PDGF/AP-1/CREB/CREBBP/MYC Expression Targets | |
| PDGF/STAT Expression Targets | |
| TCR/NFAT Expression Targets | |
| TGFA/AP-1/ATF Expression Targets | |
| VEGFA/AP-1/CREBBP/MYC Expression Targets | |
| AREG/CTNN Expression Targets | |
| BTC/AP-1/ATF/CREB Expression Targets | |
| BTC/CTNN Expression Targets | |
| EGF/CTNN Expression Targets | |
| scatter factor-hepatocyte growth factor signaling pathway | |
| mitochondrial autophagy pathway |
| Group | Src |
|---|---|
| Oncogenes | |
| immune system process | |
| oogenesis | |
| uterus development | |
| leukocyte migration | |
| Fc-gamma receptor signaling pathway involved in phagocytosis | |
| innate immune response | |
| T cell costimulation | |
| cell proliferation | |
| positive regulation of MAP kinase activity | |
| positive regulation of ERK1 and ERK2 cascade | |
| positive regulation of glucose metabolic process | |
| positive regulation of phosphatidylinositol 3-kinase activity | |
| bone resorption | |
| regulation of bone resorption | |
| branching involved in mammary gland duct morphogenesis | |
| positive regulation of cytokine secretion | |
| blood coagulation | |
| platelet activation | |
| regulation of vascular permeability | |
| forebrain development | |
| axon guidance | |
| cell cycle | |
| cell adhesion | |
| positive regulation of cyclin-dependent protein kinase activity | |
| signal transduction | |
| intracellular signal transduction | |
| positive regulation of intracellular signal transduction | |
| Ras protein signal transduction | |
| negative regulation of intrinsic apoptotic signaling pathway | |
| positive regulation of protein kinase B signaling | |
| negative regulation of extrinsic apoptotic signaling pathway | |
| positive regulation of insulin receptor signaling pathway | |
| positive regulation of platelet-derived growth factor receptor signaling pathway | |
| SH3-SH2 adaptor activity | |
| positive regulation of canonical Wnt signaling pathway | |
| signal complex assembly | |
| regulation of intracellular estrogen receptor signaling pathway | |
| progesterone receptor signaling pathway | |
| neurotrophin TRK receptor signaling pathway | |
| fibroblast growth factor receptor signaling pathway | |
| epidermal growth factor receptor signaling pathway | |
| cell-cell adhesion | |
| positive regulation of cell adhesion | |
| negative regulation of focal adhesion assembly | |
| cell migration | |
| positive regulation of smooth muscle cell migration | |
| positive regulation of apoptotic process | |
| negative regulation of apoptotic process | |
| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process | |
| negative regulation of anoikis | |
| adherens junction organization | |
| transcytosis | |
| response to drug | |
| response to fatty acid | |
| response to hydrogen peroxide | |
| cellular response to insulin stimulus | |
| cellular response to lipopolysaccharide | |
| cellular response to progesterone stimulus | |
| cellular response to fatty acid | |
| cellular response to hypoxia | |
| response to mineralocorticoid | |
| response to interleukin-1 | |
| response to mechanical stimulus | |
| response to virus | |
| response to nutrient levels | |
| response to electrical stimulus | |
| response to acidity | |
| positive regulation of DNA biosynthetic process | |
| positive regulation of transcription, DNA-templated | |
| positive regulation of protein autophosphorylation | |
| activation of protein kinase B activity | |
| positive regulation of gene expression | |
| positive regulation of podosome assembly | |
| positive regulation of integrin activation | |
| positive regulation of protein transport | |
| negative regulation of protein homooligomerization | |
| negative regulation of transcription, DNA-templated | |
| negative regulation of mitochondrial depolarization | |
| transferase activity | |
| transferase activity, transferring phosphorus-containing groups | |
| kinase activity | |
| protein kinase activity | |
| protein tyrosine kinase activity | |
| non-membrane spanning protein tyrosine kinase activity | |
| protein phosphorylation | |
| peptidyl-serine phosphorylation | |
| peptidyl-tyrosine phosphorylation | |
| protein autophosphorylation | |
| phosphorylation | |
| modulation by virus of host morphology or physiology | |
| regulation of protein binding | |
| protein complex binding | |
| phosphoprotein binding | |
| ion channel binding | |
| protein domain specific binding | |
| protein C-terminus binding | |
| cell adhesion molecule binding | |
| enzyme binding | |
| receptor binding | |
| integrin binding | |
| insulin receptor binding | |
| growth factor receptor binding | |
| ephrin receptor binding | |
| estrogen receptor binding | |
| protein kinase binding | |
| protein kinase C binding | |
| SH2 domain binding | |
| nucleotide binding | |
| ATP binding | |
| heme binding | |
| membrane | |
| caveola | |
| mitochondrial inner membrane | |
| postsynaptic density | |
| plasma membrane | |
| cytoplasm | |
| cytosol | |
| mitochondrion | |
| lysosome | |
| late endosome | |
| cytoskeleton | |
| nucleus | |
| neuron projection | |
| Proteins Involved in Pathogenesis of B-cell Acute Lymphoblastic Leukemia | |
| Proteins Involved in Pathogenesis of Cowden Syndrome | |
| Secreted proteins | |
| Biofluids assayable substances |
| Source | Curated |
|---|
| LocusLink ID | 6714 |
|---|---|
| 20779 | |
| 83805 | |
| 99351 |
| Cell Localization | Cytoplasm |
|---|---|
| Cell membrane | |
| Mitochondrion inner membrane | |
| Nucleus | |
| Cytoskeleton |
| GO ID | 0005524 |
|---|---|
| 0042169 | |
| 0005070 | |
| 0046875 | |
| 0070851 | |
| 0020037 | |
| 0005178 | |
| 0044325 | |
| 0016301 | |
| 0004715 | |
| 0051219 | |
| 0004672 | |
| 0004713 | |
| 0005102 | |
| 0038096 | |
| 0007265 | |
| 0031295 | |
| 0007411 | |
| 0007596 | |
| 0045453 | |
| 0060444 | |
| 0007155 | |
| 0007049 | |
| 0071393 | |
| 0007173 | |
| 0008543 | |
| 0030900 | |
| 0045087 | |
| 0035556 | |
| 0050900 | |
| 0019048 | |
| 2000811 | |
| 0043066 | |
| 0043154 | |
| 2001237 | |
| 0051895 | |
| 2001243 | |
| 0051902 | |
| 0032463 | |
| 0048011 | |
| 0048477 | |
| 0018108 | |
| 0030168 | |
| 0070374 | |
| 0090263 | |
| 0033625 | |
| 0071803 | |
| 0051897 | |
| 0050847 | |
| 0046777 | |
| 0045124 | |
| 0033146 | |
| 0043393 | |
| 0043114 | |
| 0070555 | |
| 0007172 | |
| 0007165 | |
| 0060065 | |
| 0005901 | |
| 0005737 | |
| 0005856 | |
| 0005829 | |
| 0005770 | |
| 0005764 | |
| 0005743 | |
| 0005739 | |
| 0005634 | |
| 0005886 | |
| 0050839 | |
| 0019899 | |
| 0030331 | |
| 0005158 | |
| 0000166 | |
| 0008022 | |
| 0032403 | |
| 0019904 | |
| 0005080 | |
| 0019901 | |
| 0016740 | |
| 0016772 | |
| 0032148 | |
| 0034332 | |
| 0016477 | |
| 0008283 | |
| 0002376 | |
| 0045892 | |
| 0018105 | |
| 0016310 | |
| 2000573 | |
| 0043406 | |
| 0043065 | |
| 0045785 | |
| 0045737 | |
| 0050715 | |
| 0010628 | |
| 0010907 | |
| 0046628 | |
| 0043552 | |
| 0031954 | |
| 0051222 | |
| 0014911 | |
| 0045893 | |
| 0006468 | |
| 0045056 | |
| 0016020 | |
| 0043005 | |
| 0014069 | |
| 0016337 | |
| 0071398 | |
| 0071456 | |
| 0032869 | |
| 0071222 | |
| 1902533 | |
| 0010641 | |
| 0010447 | |
| 0042493 | |
| 0051602 | |
| 0070542 | |
| 0042542 | |
| 0009612 | |
| 0051385 | |
| 0031667 | |
| 0009615 | |
| 0005515 | |
| 0007243 | |
| 0051726 | |
| 0005622 | |
| 0048008 | |
| 0001101 | |
| 0006950 | |
| 0016021 | |
| 0004674 | |
| 0000074 | |
| 0004872 | |
| 0007242 | |
| 0050875 |
| Alias | ASV |
|---|---|
| SRC1 | |
| c-SRC | |
| p60-Src | |
| RP5-823N20.1 | |
| proto-oncogene tyrosine-protein kinase Src | |
| proto-oncogene c-Src | |
| tyrosine kinase pp60c-src | |
| tyrosine-protein kinase SRC-1 | |
| protooncogene SRC, Rous sarcoma | |
| AW259666 | |
| pp60c-src | |
| RP23-169M4.1 | |
| neuronal proto-oncogene tyrosine-protein kinase Src | |
| Rous sarcoma oncogene | |
| tyrosine protein kinase c-src | |
| tyrosine protein kinase pp60-c-src | |
| v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog | |
| Schmidt-Ruppin A-2 viral oncogene homolog | |
| v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog | |
| Src PTK | |
| SRC | |
| SRC I | |
| Src protein kinase | |
| SRC-1 kinase | |
| v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) | |
| Src tyrosine kinase | |
| v-Src | |
| tyrosine kinase SRC-1 | |
| OTTHUMP00000174476 | |
| c-Src tyrosine kinase | |
| OTTHUMP00000174477 | |
| OTTHUMP00000174478 | |
| OTTMUSP00000017316 | |
| OTTMUSP00000019027 | |
| protooncogene src | |
| OTTMUSP00000019028 | |
| p60c-src | |
| OTTMUSP00000019029 | |
| expressed sequence AW259666 | |
| Schmidt-Ruppin A-2) viral oncogene homolog | |
| SRC SH2-domain | |
| SRC SH3-domain | |
| tyrosine protein kinase SRC-1 | |
| SRC protein tyrosine kinase |
| Mouse chromosome position | 2 78.35 cM |
|---|---|
| 2 89.0 cM |
| OMIM ID | 190090 |
|---|
| Rat chromosome position | 3q42 |
|---|
| Hugo ID | 11283 |
|---|
| Human chromosome position | 20q12-q13 |
|---|
| Swiss-Prot Accession | P12931 |
|---|---|
| P05480 | |
| Q80XU2 | |
| Q9WUD9 | |
| G3V776 | |
| Q45QJ2 | |
| Q9JJ10 | |
| Q2M4I4 | |
| E1P5V4 | |
| Q76P87 | |
| Q86VB9 | |
| Q9H5A8 | |
| Q71UK5 | |
| Q9H7V3 |
| PIR ID | A43610 |
|---|---|
| A26891 |
| Unigene ID | Hs.195659 |
|---|---|
| Mm.22845 | |
| Rn.112600 |
| KEGG ID | hsa:6714 |
|---|---|
| mmu:20779 | |
| rno:83805 |
| Swiss-Prot ID | SRC_RAT |
|---|---|
| SRC_MOUSE | |
| SRC_HUMAN |
| EC Number | 2.7.10.2 |
|---|---|
| 2.7.1.112 |
| Ensembl ID | ENSG00000197122 |
|---|---|
| ENSP00000408503 | |
| ENST00000445403 | |
| ENSP00000362680 | |
| ENST00000373578 | |
| ENSMUSG00000027646 | |
| ENSMUSP00000029175 | |
| ENSMUST00000029175 | |
| ENSMUSP00000090237 | |
| ENSMUST00000092576 | |
| ENSRNOG00000009495 | |
| ENSRNOP00000012739 | |
| ENSRNOT00000012739 |
| Homologene ID | 21120 |
|---|
| Organism | Homo sapiens |
|---|---|
| Mus musculus | |
| Rattus norvegicus |
| MGI ID | 98397 |
|---|---|
| 2139334 |
| RGD ID | 620795 |
|---|
| MedScan ID | 6714 |
|---|