| URN | urn:agi-llid:3658 |
|---|---|
| Total Entities | 0 |
| Connectivity | 255 |
| Name | Ireb2 |
| Description | iron-responsive element binding protein 2 |
| Notes | RNA-binding proteins that bind iron-responsive elements (IREs) [RGD, Feb 2006] |
| GO Molecular Function | translation repressor activity |
|---|---|
| RNA binding | |
| iron-responsive element binding | |
| metal ion binding | |
| iron-sulfur cluster binding | |
| 4 iron, 4 sulfur cluster binding |
| GO Cellular Component | cytoplasm |
|---|---|
| Golgi apparatus | |
| cytosol | |
| endoplasmic reticulum | |
| mitochondrion |
| GO Biological Process | metabolic process |
|---|---|
| erythrocyte homeostasis | |
| osteoclast differentiation | |
| protoporphyrinogen IX biosynthetic process | |
| post-embryonic development | |
| intestinal absorption | |
| aging | |
| cellular iron ion homeostasis | |
| iron ion transport | |
| response to retinoic acid | |
| response to iron(II) ion | |
| cellular response to hypoxia | |
| negative regulation of translation | |
| regulation of translation | |
| regulation of gene expression | |
| iron ion homeostasis |
| Pathway | doxorubicin response pathway |
|---|
| Group | metabolic process |
|---|---|
| erythrocyte homeostasis | |
| osteoclast differentiation | |
| protoporphyrinogen IX biosynthetic process | |
| post-embryonic development | |
| intestinal absorption | |
| aging | |
| cellular iron ion homeostasis | |
| iron ion transport | |
| response to retinoic acid | |
| response to iron(II) ion | |
| cellular response to hypoxia | |
| negative regulation of translation | |
| translation repressor activity | |
| regulation of translation | |
| regulation of gene expression | |
| iron ion homeostasis | |
| RNA binding | |
| iron-responsive element binding | |
| metal ion binding | |
| iron-sulfur cluster binding | |
| 4 iron, 4 sulfur cluster binding | |
| cytoplasm | |
| Golgi apparatus | |
| cytosol | |
| endoplasmic reticulum | |
| mitochondrion |
| LocusLink ID | 3658 |
|---|---|
| 64602 | |
| 64831 |
| Cell Localization | Cytoplasm |
|---|
| GO ID | 0051539 |
|---|---|
| 0003723 | |
| 0030350 | |
| 0046872 | |
| 0007568 | |
| 0006879 | |
| 0071456 | |
| 0034101 | |
| 0050892 | |
| 0006826 | |
| 0030316 | |
| 0009791 | |
| 0006782 | |
| 0006417 | |
| 0010040 | |
| 0032526 | |
| 0005737 | |
| 0005829 | |
| 0005739 | |
| 0051536 | |
| 0030371 | |
| 0008152 | |
| 0017148 | |
| 0010468 | |
| 0005794 | |
| 0005783 | |
| 0055072 |
| Alias | ACO3 |
|---|---|
| IRP2 | |
| IRP2AD | |
| iron-responsive element-binding protein 2 | |
| IRE-BP 2 | |
| iron regulatory protein 2 | |
| D9Ertd85e | |
| iron-regulatory protein 2 | |
| Ireb2 | |
| Iron-responsive element binding protein II | |
| MGC93423 | |
| LOC146012 | |
| LOC123689 | |
| Iron regulatory protein II | |
| FLJ23381 | |
| DNA segment, Chr 9, ERATO Doi 85, expressed | |
| DKFZp564D1164 | |
| iron responsive element binding protein 2 | |
| IRE-BP II |
| Mouse chromosome position | 9 29.81 cM |
|---|
| OMIM ID | 147582 |
|---|
| Rat chromosome position | 8q24 |
|---|
| Hugo ID | 6115 |
|---|
| Human chromosome position | 15q25.1 |
|---|
| Swiss-Prot Accession | D3DW85 |
|---|---|
| P48200 | |
| Q811J3 | |
| Q62751 | |
| Q66HL4 | |
| E9QPM2 | |
| O70235 | |
| A8KAC7 | |
| Q13095 | |
| Q1HE21 | |
| Q59FQ7 | |
| Q9UF17 |
| PIR ID | A57238 |
|---|---|
| B57238 |
| Unigene ID | Hs.436031 |
|---|---|
| Mm.208991 | |
| Rn.10132 |
| KEGG ID | hsa:3658 |
|---|---|
| mmu:64602 | |
| rno:64831 |
| Swiss-Prot ID | IREB2_RAT |
|---|---|
| IREB2_MOUSE | |
| IREB2_HUMAN |
| Ensembl ID | ENSG00000136381 |
|---|---|
| ENSP00000258886 | |
| ENST00000258886 | |
| ENSMUSG00000032293 | |
| ENSMUSP00000034843 | |
| ENSMUST00000034843 | |
| ENSRNOG00000013271 | |
| ENSRNOP00000017900 | |
| ENSRNOT00000017900 |
| Homologene ID | 11280 |
|---|
| Organism | Homo sapiens |
|---|---|
| Mus musculus | |
| Rattus norvegicus |
| MGI ID | 1928268 |
|---|
| RGD ID | 621539 |
|---|
| MedScan ID | 3658 |
|---|