| URN | urn:agi-llid:11269 |
|---|---|
| Total Entities | 0 |
| Connectivity | 68 |
| Name | Ddx19b |
| Description | DEAD (Asp-Glu-Ala-Asp) box polypeptide 19B |
| Notes | DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which exhibits RNA-dependent ATPase and ATP-dependent RNA-unwinding activities. This protein is recruited to the cytoplasmic fibrils of the nuclear pore complex, where it participates in the export of mRNA from the nucleus. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
| GO Molecular Function | ATP-dependent helicase activity |
|---|---|
| hydrolase activity | |
| helicase activity | |
| nucleotide binding | |
| ATP binding | |
| RNA binding |
| GO Cellular Component | nuclear pore |
|---|---|
| nuclear membrane | |
| nuclear envelope | |
| cytoplasm |
| GO Biological Process | mRNA export from nucleus |
|---|---|
| protein transport |
| Pathway | mRNA nuclear export pathway |
|---|
| Group | Nuclear export |
|---|---|
| ATP-dependent helicase activity | |
| hydrolase activity | |
| helicase activity | |
| mRNA export from nucleus | |
| protein transport | |
| nucleotide binding | |
| ATP binding | |
| RNA binding | |
| nuclear pore | |
| nuclear membrane | |
| nuclear envelope | |
| cytoplasm |
| LocusLink ID | 11269 |
|---|---|
| 234733 |
| Cell Localization | Nucleus |
|---|---|
| Cytoplasm | |
| Nuclear pore complex | |
| Nucleus membrane |
| GO ID | 0005524 |
|---|---|
| 0008026 | |
| 0003723 | |
| 0004386 | |
| 0006406 | |
| 0015031 | |
| 0005737 | |
| 0005635 | |
| 0031965 | |
| 0005643 | |
| 0016787 | |
| 0000166 |
| Alias | DBP5 |
|---|---|
| RNAh | |
| DDX19 | |
| ATP-dependent RNA helicase DDX19B | |
| DEAD-box protein 5 | |
| yeast Dbp5 homolog | |
| DEAD box protein 19B | |
| DEAD box RNA helicase DEAD5 | |
| DEAD-box RNA helicase DEAD5 | |
| ATP-dependent RNA helicase DDX19 | |
| DEAD (Asp-Glu-Ala-As) box polypeptide 19B | |
| DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 19 (Dbp5, yeast, homolog) | |
| AW260119 | |
| 2810457M08Rik | |
| 4921519L13Rik | |
| TDBP | |
| zinc responsive protein zd10b | |
| Eif4a-rs I | |
| DEAD/H | |
| DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 19 | |
| DEAD-box protein 19 | |
| Eif4a-rs1 | |
| eukaryotic translation initiation factor 4A related sequence 1 | |
| LOC690693 | |
| mDEAD5 | |
| DEAD (Asp-Glu-Ala-Asp) box polypeptide 19b | |
| zd10b | |
| DEAD (Asp-Glu-Ala-As) box polypeptide 19 | |
| RIKEN cDNA 2810457M08 gene | |
| 2810457M08 | |
| 4921519L13 | |
| DEAD (Asp-Glu-Ala-Asp) box polypeptide 19 | |
| Asp-Glu-Ala-Asp/His) box polypeptide 19 (Dbp5, , homolog | |
| Dbp5 homolog | |
| ddx19 homolog | |
| ddx19b | |
| RIKEN cDNA 4921519L13 gene | |
| Asp-Glu-Ala-Asp/His) box polypeptide 19 (DBP5 homolog, yeast |
| Mouse chromosome position | 8 |
|---|
| OMIM ID | 605812 |
|---|
| Hugo ID | 2742 |
|---|
| Human chromosome position | 16q22.1 |
|---|
| Swiss-Prot Accession | Q9UMR2 |
|---|---|
| B4DL69 | |
| Q8BZY3 | |
| Q8R3C7 | |
| B3KNE9 | |
| B4DXS6 | |
| E7EMK4 | |
| Q6FIB7 | |
| Q6IAE0 | |
| Q96KE7 | |
| Q9H0U0 |
| Unigene ID | Hs.221761 |
|---|---|
| Mm.482176 |
| KEGG ID | hsa:11269 |
|---|---|
| mmu:234733 |
| Swiss-Prot ID | DD19B_HUMAN |
|---|
| EC Number | 3.6.4.13 |
|---|
| Ensembl ID | ENSG00000157349 |
|---|---|
| ENSP00000377267 | |
| ENST00000393657 | |
| ENSP00000348271 | |
| ENST00000355992 | |
| ENSP00000392639 | |
| ENST00000451014 | |
| ENSP00000456757 | |
| ENST00000568625 | |
| ENSP00000456574 | |
| ENST00000563392 | |
| ENSMUSG00000033658 | |
| ENSMUSP00000038551 | |
| ENSMUST00000040241 |
| Homologene ID | 56032 |
|---|
| Organism | Homo sapiens |
|---|---|
| Mus musculus |
| MGI ID | 2148251 |
|---|
| RGD ID | 1593382 |
|---|
| MedScan ID | 11269 |
|---|