Protein Slc22a16

URN urn:agi-llid:85413
Total Entities 0
Connectivity 10
Name Slc22a16
Description solute carrier family 22 (organic cation/carnitine transporter), member 16
Notes This gene encodes a member of the organic zwitterion transporter protein family which transports carnitine. The encoded protein has also been shown to transport anticancer drugs like bleomycin (PMID: 20037140) successful treatment has been correlated with the level of activity of this transporter in tumor cells. [provided by RefSeq, Dec 2011]

GO Molecular Function transmembrane transporter activity
carnitine transmembrane transporter activity
organic cation transmembrane transporter activity
amine transmembrane transporter activity

GO Cellular Component membrane
integral component of membrane
plasma membrane

GO Biological Process spermatogenesis
single fertilization
multicellular organismal development
cell differentiation
transmembrane transport
amino acid transmembrane transport
sperm motility
ion transport
amine transport
acid secretion
carnitine transport
modified amino acid transport
organic cation transport
transport

Pathway doxorubicin pharmacokinetics pathway

Group Na+ influx co-transport
Organic anions transport
CycB
spermatogenesis
single fertilization
multicellular organismal development
cell differentiation
transmembrane transport
transmembrane transporter activity
amino acid transmembrane transport
carnitine transmembrane transporter activity
organic cation transmembrane transporter activity
amine transmembrane transporter activity
sperm motility
ion transport
amine transport
acid secretion
carnitine transport
modified amino acid transport
organic cation transport
transport
membrane
integral component of membrane
plasma membrane

LocusLink ID 85413
70840

Cell Localization Plasma membrane
Cytoplasm
Membrane
Cell membrane

GO ID 0005275
0015226
0015101
0046717
0015837
0015879
0030154
0007275
0015695
0007338
0030317
0007283
0055085
0016021
0005886
0022857
0003333
0006811
0072337
0006810
0016020

Alias CT2
OAT6
OCT6
OKB1
FLIPT2
dJ261K5.1
RP1-261K5.1
solute carrier family 22 member 16
flipt 2
WUGSC:RG331P03.1
carnitine transporter 2
organic cation transporter 6
fly-like putative transporter 2
organic cation transporter OKB1
organic cation/carnitine transporter 6
fly-like putative organic ion transporter 2
solute carrier family 22 (organic cation transporter), member 16
4921504E14Rik
OTTHUMP00000017785
OTTHUMP00000017786
OTTHUMP00000040478
OTTMUSP00000028480
SLC22A16
solute carrier family 22, member 16
solute carrier family 22 (organic cation/carnitine transporter), member 16
carnitine transporter II
4921504E14
organic cation transporter VI
dJ261K5
fly-like organic ion transporter II
LOC115715
MGC118295
OKB I
fly-like organic ion transporter 2

Mouse chromosome position 10

OMIM ID 608276

Hugo ID 20302

Human chromosome position 6q22.1

Swiss-Prot Accession Q86VW1
B2RRB7
Q497L8
O14567
Q5JXM1
Q8IUG8
Q8IZD5
Q96M90
Q96RU0
Q3LVC1

GenBank ID NC_000006
NM_033125
NP_149116
XM_005267183
XP_005267240
XM_005267184
XP_005267241
XM_005267185
XP_005267242
NC_018917
AC_000138
ABBA01026118
ABBA01026119
AC002464
AAB67044
AL050350
AMYH02014286
CH471051
EAW48313
EAW48314
EAW48315
AB055798
BAC23062
AF268892
AAK58593
AI632467
AK057306
BAB71419
AK304546
BAG65342
AY145502
AAN52928
BC012014
AAH12014
BC037247
BC047565
AAH47565
Q86VW1
JF432782
ADZ15999
NC_000076
XM_006512850
XP_006512913
NM_027572
NP_081848
AC_000032
AAHY01084935
AAHY01084936
AC139760
AC157652
CH466540
EDL04956
AK014809
BC100473
AAI00474
BC138326
AAI38327
BC138327
AAI38328
DQ164804
ABA10822
DQ164805
ABA10823
Q497L8

Unigene ID Hs.520319
Mm.332570

KEGG ID hsa:85413
mmu:70840

Swiss-Prot ID S22AG_HUMAN
S22AG_MOUSE

Ensembl ID ENSG00000004809
ENSP00000357915
ENST00000368919
ENSP00000328583
ENST00000330550
ENSP00000395642
ENST00000451557
ENSMUSG00000019834
ENSMUSP00000077428
ENSMUST00000078314

Homologene ID 41957

Organism Homo sapiens
Mus musculus

MGI ID 1918090

RGD ID 1592810

MedScan ID 85413