| URN | urn:agi-llid:213 |
|---|---|
| Total Entities | 0 |
| Connectivity | 5064 |
| Name | Alb |
| Description | albumin |
| Notes | Albumin is a soluble, monomeric protein which comprises about one-half of the blood serum protein. Albumin functions primarily as a carrier protein for steroids, fatty acids, and thyroid hormones and plays a role in stabilizing extracellular fluid volume. Albumin is a globular unglycosylated serum protein of molecular weight 65,000. Albumin is synthesized in the liver as preproalbumin which has an N-terminal peptide that is removed before the nascent protein is released from the rough endoplasmic reticulum. The product, proalbumin, is in turn cleaved in the Golgi vesicles to produce the secreted albumin. [provided by RefSeq, Jul 2008] |
| Ariadne Ontology | Lipid transport |
|---|---|
| Secreted proteins | |
| Biofluids assayable substances |
| GO Molecular Function | antioxidant activity |
|---|---|
| cell surface binding | |
| lipid binding | |
| drug binding | |
| oxygen binding | |
| toxin binding | |
| chaperone binding | |
| enzyme binding | |
| pyridoxal phosphate binding | |
| fatty acid binding | |
| DNA binding | |
| metal ion binding | |
| zinc ion binding | |
| copper ion binding |
| GO Cellular Component | extracellular region |
|---|---|
| platelet alpha granule lumen | |
| protein complex | |
| cytoplasm | |
| extracellular space | |
| basement membrane |
| GO Biological Process | hemolysis by symbiont of host erythrocytes |
|---|---|
| transmembrane transport | |
| cellular response to starvation | |
| negative regulation of programmed cell death | |
| negative regulation of apoptotic process | |
| platelet activation | |
| platelet degranulation | |
| bile acid metabolic process | |
| lipoprotein metabolic process | |
| maintenance of mitochondrion location | |
| response to stress | |
| response to organic substance | |
| response to nutrient | |
| response to mercury ion | |
| response to platinum ion | |
| positive regulation of circadian sleep-wake cycle, non-REM sleep | |
| vasodilation | |
| blood coagulation | |
| transport | |
| sodium-independent organic anion transport | |
| bile acid and bile salt transport | |
| lipid metabolic process | |
| small molecule metabolic process |
| Pathway | GH1-GHR/NF-kB/ELK-SRF/MYC Expression Targets |
|---|---|
| GH1-GHR/STAT Expression Targets | |
| OSM-OSMR Expression Targets | |
| organophosphate response pathway |
| Group | Lipid transport |
|---|---|
| hemolysis by symbiont of host erythrocytes | |
| transmembrane transport | |
| cellular response to starvation | |
| negative regulation of programmed cell death | |
| negative regulation of apoptotic process | |
| platelet activation | |
| platelet degranulation | |
| bile acid metabolic process | |
| lipoprotein metabolic process | |
| maintenance of mitochondrion location | |
| response to stress | |
| response to organic substance | |
| response to nutrient | |
| response to mercury ion | |
| response to platinum ion | |
| positive regulation of circadian sleep-wake cycle, non-REM sleep | |
| vasodilation | |
| blood coagulation | |
| transport | |
| sodium-independent organic anion transport | |
| bile acid and bile salt transport | |
| lipid metabolic process | |
| small molecule metabolic process | |
| antioxidant activity | |
| cell surface binding | |
| lipid binding | |
| drug binding | |
| oxygen binding | |
| toxin binding | |
| chaperone binding | |
| enzyme binding | |
| pyridoxal phosphate binding | |
| fatty acid binding | |
| DNA binding | |
| metal ion binding | |
| zinc ion binding | |
| copper ion binding | |
| extracellular region | |
| platelet alpha granule lumen | |
| protein complex | |
| cytoplasm | |
| extracellular space | |
| basement membrane | |
| Secreted proteins | |
| Biofluids assayable substances |
| MedScan ID | 213 |
|---|
| Hugo ID | 399 |
|---|
| Human chromosome position | 4q13.3 |
|---|
| LocusLink ID | 213 |
|---|---|
| 11657 | |
| 24186 |
| Alias | PRO0883 |
|---|---|
| PRO0903 | |
| PRO1341 | |
| GIG20 | |
| serum albumin | |
| albumin (32 AA) | |
| albumin (AA 34) | |
| growth-inhibiting protein 20 | |
| cell growth inhibiting protein 42 | |
| Alb1 | |
| Alb-1 | |
| albumin 1 | |
| Albza | |
| DKFZp779N1935 | |
| PEPT | |
| PEPT_2 | |
| serum albumin variant | |
| Alb I | |
| albumin | |
| ALB | |
| albumin I | |
| albumins |
| Organism | Homo sapiens |
|---|---|
| Mus musculus | |
| Rattus norvegicus |
| OMIM ID | 103600 |
|---|---|
| 194470 |
| Unigene ID | Hs.418167 |
|---|---|
| Hs.592379 | |
| Mm.16773 | |
| Rn.202968 |
| KEGG ID | hsa:213 |
|---|---|
| mmu:11657 | |
| rno:24186 |
| Swiss-Prot Accession | P02768 |
|---|---|
| P07724 | |
| Q546G4 | |
| P02770 | |
| P11382 | |
| Q5U3X3 | |
| O95574 | |
| P04277 | |
| Q13140 | |
| Q645G4 | |
| Q68DN5 | |
| Q6UXK4 | |
| Q86YG0 | |
| Q9P157 | |
| Q9P1I7 | |
| Q9UHS3 | |
| Q9UJZ0 | |
| Q3TV03 | |
| Q61802 | |
| Q8C7C7 | |
| Q8C7H3 | |
| Q8CG74 |
| EC Number | 6.1.1.16 |
|---|
| GO ID | 0003677 |
|---|---|
| 0016209 | |
| 0043498 | |
| 0051087 | |
| 0005507 | |
| 0008144 | |
| 0019899 | |
| 0005504 | |
| 0019825 | |
| 0030170 | |
| 0015643 | |
| 0008270 | |
| 0015721 | |
| 0008206 | |
| 0007596 | |
| 0009267 | |
| 0019836 | |
| 0006629 | |
| 0042157 | |
| 0051659 | |
| 0043066 | |
| 0043069 | |
| 0030168 | |
| 0002576 | |
| 0046010 | |
| 0046689 | |
| 0007584 | |
| 0010033 | |
| 0070541 | |
| 0044281 | |
| 0043252 | |
| 0055085 | |
| 0006810 | |
| 0005604 | |
| 0005576 | |
| 0005615 | |
| 0031093 | |
| 0043234 | |
| 0008289 | |
| 0046872 | |
| 0006950 | |
| 0005737 | |
| 0042311 |
| PIR ID | A93872 |
|---|---|
| A93743 | |
| A05139 |
| Swiss-Prot ID | ALBU_RAT |
|---|---|
| ALBU_HUMAN | |
| ALBU_MOUSE |
| Cell Localization | Secreted |
|---|---|
| Plasma membrane |
| IPI ID | IPI00191737 |
|---|---|
| IPI00384697 | |
| IPI00745872 | |
| IPI00131695 |
| Mouse chromosome position | 5 50.0 cM |
|---|
| Rat chromosome position | 14p22 |
|---|
| Homologene ID | 405 |
|---|
| MGI ID | 87991 |
|---|
| RGD ID | 2085 |
|---|
| Primary Cell Localization | Plasma membrane |
|---|