| URN | urn:agi-llid:60588 |
|---|---|
| Total Entities | 0 |
| Connectivity | 10 |
| Name | Ache |
| Description | acetylcholinesterase |
| Notes | catalyzes the hydrolysis of acetylcholine to choline and acetate; plays a role in neuronal development and synapse formation [RGD, Feb 2006] |
| Ariadne Ontology | Phospholipid biosynthesis |
|---|
| GO Molecular Function | collagen binding |
|---|---|
| laminin binding | |
| protein self-association | |
| protein homodimerization activity | |
| choline binding | |
| acetylcholine binding | |
| hydrolase activity | |
| serine hydrolase activity | |
| carboxylesterase activity | |
| cholinesterase activity | |
| acetylcholinesterase activity |
| GO Cellular Component | cell junction |
|---|---|
| membrane | |
| extracellular region | |
| synapse | |
| nuclear envelope | |
| endoplasmic reticulum lumen | |
| anchored to membrane | |
| plasma membrane | |
| cell surface | |
| cytoplasm | |
| perinuclear region of cytoplasm | |
| Golgi apparatus | |
| rough endoplasmic reticulum | |
| neuron projection | |
| axon | |
| dendrite | |
| neuronal cell body | |
| extracellular space | |
| basal lamina | |
| presynaptic membrane | |
| postsynaptic membrane | |
| neuromuscular junction |
| GO Biological Process | cell adhesion |
|---|---|
| synaptic transmission, cholinergic | |
| regulation of receptor recycling | |
| positive regulation of dendrite morphogenesis | |
| positive regulation of axonogenesis | |
| osteoblast development | |
| choline metabolic process | |
| receptor internalization | |
| neurotransmitter receptor biosynthetic process | |
| acetylcholine catabolic process | |
| acetylcholine metabolic process | |
| neuron death | |
| synapse assembly | |
| retina development in camera-type eye | |
| protein tetramerization |
| Pathway | acetylcholine signaling pathway via muscarinic acetylcholine receptor |
|---|---|
| acetylcholine signaling pathway via nicotinic acetylcholine receptor | |
| organophosphate response pathway |
| Group | Phospholipid biosynthesis |
|---|---|
| cell adhesion | |
| synaptic transmission, cholinergic | |
| regulation of receptor recycling | |
| positive regulation of dendrite morphogenesis | |
| positive regulation of axonogenesis | |
| osteoblast development | |
| choline metabolic process | |
| receptor internalization | |
| neurotransmitter receptor biosynthetic process | |
| acetylcholine catabolic process | |
| acetylcholine metabolic process | |
| neuron death | |
| synapse assembly | |
| retina development in camera-type eye | |
| protein tetramerization | |
| collagen binding | |
| laminin binding | |
| protein self-association | |
| protein homodimerization activity | |
| choline binding | |
| acetylcholine binding | |
| hydrolase activity | |
| serine hydrolase activity | |
| carboxylesterase activity | |
| cholinesterase activity | |
| acetylcholinesterase activity | |
| cell junction | |
| membrane | |
| extracellular region | |
| synapse | |
| nuclear envelope | |
| endoplasmic reticulum lumen | |
| anchored to membrane | |
| plasma membrane | |
| cell surface | |
| cytoplasm | |
| perinuclear region of cytoplasm | |
| Golgi apparatus | |
| rough endoplasmic reticulum | |
| neuron projection | |
| axon | |
| dendrite | |
| neuronal cell body | |
| extracellular space | |
| basal lamina | |
| presynaptic membrane | |
| postsynaptic membrane | |
| neuromuscular junction |
| MedScan ID | 60588 |
|---|
| GenBank ID | NC_005111 |
|---|---|
| NM_172009 | |
| NP_742006 | |
| AC_000080 | |
| AF134349 | |
| AAD27645 | |
| CH473973 | |
| EDM13278 | |
| X71089 | |
| BC094521 | |
| AAH94521 | |
| S50879 | |
| AAB24586 | |
| X70140 | |
| CAA49717 | |
| X70141 | |
| CAA49718 | |
| P37136 | |
| AY555735 |
| LocusLink ID | 83817 |
|---|---|
| 60588 |
| Alias | acetylcholinesterase |
|---|---|
| glycolipid-anchored form of acetylcholinesterase |
| Organism | Rattus norvegicus |
|---|
| Unigene ID | Rn.105879 |
|---|
| KEGG ID | rno:83817 |
|---|
| Swiss-Prot Accession | P37136 |
|---|
| EC Number | 3.1.1.7 |
|---|
| GO ID | 0042166 |
|---|---|
| 0003990 | |
| 0004091 | |
| 0033265 | |
| 0004104 | |
| 0005518 | |
| 0016787 | |
| 0043236 | |
| 0042803 | |
| 0043621 | |
| 0017171 | |
| 0006581 | |
| 0008291 | |
| 0007155 | |
| 0019695 | |
| 0070997 | |
| 0045212 | |
| 0002076 | |
| 0050772 | |
| 0050775 | |
| 0051262 | |
| 0031623 | |
| 0001919 | |
| 0060041 | |
| 0007416 | |
| 0007271 | |
| 0005794 | |
| 0031225 | |
| 0030424 | |
| 0005605 | |
| 0030054 | |
| 0009986 | |
| 0005737 | |
| 0030425 | |
| 0005788 | |
| 0005576 | |
| 0005615 | |
| 0016020 | |
| 0031594 | |
| 0043005 | |
| 0043025 | |
| 0005635 | |
| 0048471 | |
| 0005886 | |
| 0045211 | |
| 0042734 | |
| 0005791 | |
| 0045202 |
| PIR ID | JH0811 |
|---|
| Swiss-Prot ID | ACES_RAT |
|---|
| Cell Localization | Cell junction |
|---|---|
| synapse | |
| Secreted | |
| Cell membrane | |
| Cytoplasm |
| IPI ID | IPI00203357 |
|---|---|
| IPI00231569 | |
| IPI00231570 |
| Rat chromosome position | 12 |
|---|
| RGD ID | 69313 |
|---|
| Primary Cell Localization | Cytoplasm |
|---|