| URN | urn:agi-llid:60 |
|---|---|
| Total Entities | 0 |
| Connectivity | 952 |
| Name | Actb |
| Description | actin, beta |
| Notes | This gene encodes one of six different actin proteins. Actins are highly conserved proteins that are involved in cell motility, structure, and integrity. This actin is a major constituent of the contractile apparatus and one of the two nonmuscle cytoskeletal actins. [provided by RefSeq, Jul 2008] |
| Ariadne Ontology | Actomyosin based movement |
|---|---|
| Actin-based cytoskeleton assembly | |
| Secreted proteins | |
| Biofluids assayable substances |
| GO Molecular Function | Tat protein binding |
|---|---|
| nitric-oxide synthase binding | |
| protein kinase binding | |
| kinesin binding | |
| nucleotide binding | |
| ATP binding | |
| structural constituent of cytoskeleton |
| GO Cellular Component | NuA4 histone acetyltransferase complex |
|---|---|
| MLL5-L complex | |
| postsynaptic density | |
| protein complex | |
| ribonucleoprotein complex | |
| cytoplasm | |
| cytosol | |
| cortical cytoskeleton | |
| cytoskeleton | |
| axon |
| GO Biological Process | cellular component movement |
|---|---|
| axonogenesis | |
| cellular protein metabolic process | |
| protein folding | |
| 'de novo' posttranslational protein folding | |
| cell junction assembly | |
| cell-cell junction organization | |
| adherens junction organization | |
| response to calcium ion | |
| axon guidance | |
| blood coagulation |
| Pathway | SWI/SNF BRG1/BAF Chromatin Remodeling |
|---|---|
| SWI/SNF BRG1/PBAF Chromatin Remodeling | |
| SWI/SNF BRM/BAF Chromatin Remodeling | |
| TRRAP/TIP60 Chromatin Remodeling | |
| IL2 Expression Targets | |
| IGF1/STAT Expression Targets | |
| Insulin/ELK-SRF/HIF1A/MYC/SREBF Expression Targets | |
| Insulin/STAT Expression Targets | |
| IGF1/ELK-SRF/HIF1A/MYC/SREBF Expression Targets | |
| IGF1/MEF/MYOD/MYOG Expression Targets | |
| Insulin/CEBPA/CTNNB/FOXA/FOXO Expression Targets | |
| Insulin/MEF/MYOD Expression Targets | |
| auditory mechanotransduction pathway |
| Group | Actomyosin based movement |
|---|---|
| Actin-based cytoskeleton assembly | |
| cellular component movement | |
| axonogenesis | |
| cellular protein metabolic process | |
| protein folding | |
| 'de novo' posttranslational protein folding | |
| cell junction assembly | |
| cell-cell junction organization | |
| adherens junction organization | |
| response to calcium ion | |
| axon guidance | |
| blood coagulation | |
| Tat protein binding | |
| nitric-oxide synthase binding | |
| protein kinase binding | |
| kinesin binding | |
| nucleotide binding | |
| ATP binding | |
| structural constituent of cytoskeleton | |
| NuA4 histone acetyltransferase complex | |
| MLL5-L complex | |
| postsynaptic density | |
| protein complex | |
| ribonucleoprotein complex | |
| cytoplasm | |
| cytosol | |
| cortical cytoskeleton | |
| cytoskeleton | |
| axon | |
| Secreted proteins | |
| Biofluids assayable substances |
| MedScan ID | 60 |
|---|
| Hugo ID | 132 |
|---|
| Human chromosome position | 7p22 |
|---|
| LocusLink ID | 60 |
|---|---|
| 11461 | |
| 81822 |
| Alias | BRWS1 |
|---|---|
| PS1TP5BP1 | |
| actin, cytoplasmic 1 | |
| beta cytoskeletal actin | |
| PS1TP5-binding protein 1 | |
| Actx | |
| beta-actin | |
| E430023M04Rik | |
| melanoma X-actin | |
| A-X actin-like protein | |
| actin, beta, cytoplasmic | |
| cytoplasmic beta-actin | |
| Actb | |
| cytoplasmic actin, beta | |
| E430023M04 | |
| LOC115571 | |
| cytoplasmic actin | |
| beta actin | |
| Actin, cytoplasmic I | |
| actin, beta |
| Organism | Homo sapiens |
|---|---|
| Mus musculus | |
| Rattus norvegicus |
| OMIM ID | 102630 |
|---|---|
| 243310 | |
| 607371 |
| Unigene ID | Hs.520640 |
|---|---|
| Mm.328431 | |
| Mm.391967 | |
| Rn.94978 |
| KEGG ID | hsa:60 |
|---|---|
| mmu:11461 | |
| rno:81822 |
| Swiss-Prot Accession | P60709 |
|---|---|
| Q1KLZ0 | |
| B2RRX1 | |
| P60710 | |
| P60711 | |
| P02570 | |
| P70514 | |
| P99021 | |
| Q11211 | |
| Q64316 | |
| Q75MN2 | |
| Q96B34 | |
| Q96HG5 | |
| Q3TI89 | |
| Q3TVP6 | |
| Q6ZWM3 |
| GO ID | 0005524 |
|---|---|
| 0030957 | |
| 0019894 | |
| 0050998 | |
| 0019901 | |
| 0005200 | |
| 0051084 | |
| 0034332 | |
| 0007411 | |
| 0007596 | |
| 0034329 | |
| 0045216 | |
| 0006928 | |
| 0044267 | |
| 0006457 | |
| 0051592 | |
| 0070688 | |
| 0035267 | |
| 0030424 | |
| 0030863 | |
| 0005737 | |
| 0005856 | |
| 0005829 | |
| 0030529 | |
| 0000166 | |
| 0007409 | |
| 0014069 | |
| 0043234 |
| PIR ID | A25168 |
|---|---|
| A39104 |
| Swiss-Prot ID | ACTB_HUMAN |
|---|---|
| ACTB_RAT | |
| ACTB_MOUSE |
| Cell Localization | Cytoplasm |
|---|---|
| cytoskeleton |
| IPI ID | IPI00021439 |
|---|---|
| IPI00189819 | |
| IPI00110850 |
| Mouse chromosome position | 5 80.0 cM |
|---|
| Rat chromosome position | 12p11 |
|---|
| Homologene ID | 110648 |
|---|
| MGI ID | 87904 |
|---|
| RGD ID | 628837 |
|---|
| Primary Cell Localization | Cytoplasm |
|---|