| URN | urn:agi-llid:5357 |
|---|---|
| Total Entities | 0 |
| Connectivity | 7 |
| Name | Pls1 |
| Description | plastin 1 |
| Notes | Plastins are a family of actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes. In humans, two ubiquitous plastin isoforms (L and T) have been identified. The protein encoded by this gene is a third distinct plastin isoform, which is specifically expressed at high levels in the small intestine. Alternatively spliced transcript variants varying in the 5' UTR, but encoding the same protein, have been found for this gene. A pseudogene of this gene is found on chromosome 11.[provided by RefSeq, Feb 2010] |
| Ariadne Ontology | Actin-based cytoskeleton assembly |
|---|
| GO Molecular Function | actin binding |
|---|---|
| actin filament binding | |
| calcium ion binding | |
| structural constituent of cytoskeleton |
| GO Cellular Component | cytoplasm |
|---|
| Pathway | auditory mechanotransduction pathway |
|---|
| Group | Actin-based cytoskeleton assembly |
|---|---|
| actin binding | |
| actin filament binding | |
| calcium ion binding | |
| structural constituent of cytoskeleton | |
| cytoplasm |
| MedScan ID | 5357 |
|---|
| Hugo ID | 9090 |
|---|
| Human chromosome position | 3q23 |
|---|
| LocusLink ID | 5357 |
|---|---|
| 102502 | |
| 315926 |
| Alias | plastin-1 |
|---|---|
| fimbrin | |
| I plastin | |
| intestine specific plastin | |
| intestine-specific plastin | |
| AI427122 | |
| I-fimbrin | |
| plastin 1, I | |
| plastin 1 (I isoform) | |
| I-plastin | |
| PLS I | |
| Plastin I | |
| plastin 1 | |
| MGC189074 | |
| I isoform plastin I | |
| I isoform plastin 1 | |
| LOC194483 | |
| LOC235532 |
| Organism | Homo sapiens |
|---|---|
| Mus musculus | |
| Rattus norvegicus |
| OMIM ID | 602734 |
|---|
| Unigene ID | Hs.203637 |
|---|---|
| Mm.11869 | |
| Rn.224870 |
| KEGG ID | hsa:5357 |
|---|---|
| mmu:102502 | |
| rno:315926 |
| Swiss-Prot Accession | Q14651 |
|---|---|
| Q3V0K9 | |
| Q3V3X1 | |
| B5DEY0 | |
| A8K2Q1 | |
| D3DNG3 | |
| Q8NEG6 |
| GO ID | 0051015 |
|---|---|
| 0005509 | |
| 0005200 | |
| 0005737 | |
| 0003779 |
| PIR ID | A56536 |
|---|
| Swiss-Prot ID | PLSI_HUMAN |
|---|---|
| PLSI_MOUSE |
| Cell Localization | Cytoplasm |
|---|
| IPI ID | IPI00032304 |
|---|---|
| IPI00344681 |
| Mouse chromosome position | 9 |
|---|
| Rat chromosome position | 8q31 |
|---|
| Homologene ID | 68270 |
|---|
| MGI ID | 104809 |
|---|
| RGD ID | 1307142 |
|---|
| Primary Cell Localization | Cytoplasm |
|---|