| URN | urn:agi-llid:131890 |
|---|---|
| Total Entities | 0 |
| Connectivity | 16 |
| Name | GRK7 |
| Description | G protein-coupled receptor kinase 7 |
| Notes | This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. It is specifically expressed in the retina and the encoded protein has been shown to phosphorylate cone opsins and initiate their deactivation. [provided by RefSeq] |
| Ariadne Ontology | GRK |
|---|
| GO Molecular Function | ATP binding |
|---|---|
| rhodopsin kinase activity | |
| G-protein coupled receptor kinase activity |
| GO Cellular Component | membrane |
|---|
| GO Biological Process | termination of G-protein coupled receptor signaling pathway |
|---|---|
| signal transduction | |
| protein autophosphorylation | |
| visual perception |
| Pathway | visual phototransduction pathway |
|---|---|
| altered visual phototransduction pathway |
| Group | GRK |
|---|---|
| termination of G-protein coupled receptor signaling pathway | |
| signal transduction | |
| protein autophosphorylation | |
| visual perception | |
| ATP binding | |
| rhodopsin kinase activity | |
| G-protein coupled receptor kinase activity | |
| membrane |
| MedScan ID | 131890 |
|---|
| Hugo ID | 17031 |
|---|
| Human chromosome position | 3q24 |
|---|---|
| 3q21-q23 |
| LocusLink ID | 131890 |
|---|
| Alias | GPRK7 |
|---|---|
| G protein-coupled receptor kinase 7 | |
| g protein-coupled receptor kinase GRK7 | |
| G protein receptor kinase 7 | |
| G protein-coupled receptor kinase VII | |
| GRK7 |
| Organism | Homo sapiens |
|---|
| OMIM ID | 606987 |
|---|
| Unigene ID | Hs.680654 |
|---|
| KEGG ID | hsa:131890 |
|---|
| Swiss-Prot Accession | Q8WTQ7 |
|---|
| EC Number | 2.7.11.16 |
|---|---|
| 2.7.11.14 |
| GO ID | 0005524 |
|---|---|
| 0004703 | |
| 0050254 | |
| 0046777 | |
| 0007165 | |
| 0038032 | |
| 0007601 | |
| 0016020 | |
| 0000166 | |
| 0004871 | |
| 0016740 | |
| 0006468 | |
| 0050896 |
| Swiss-Prot ID | GRK7_HUMAN |
|---|
| Cell Localization | Membrane |
|---|---|
| Cytoplasm |
| IPI ID | IPI00102804 |
|---|
| RGD ID | 1347561 |
|---|
| Primary Cell Localization | Cytoplasm |
|---|