| URN | urn:agi-llid:44 |
|---|---|
| Total Entities | 0 |
| Connectivity | 38 |
| Name | Cnga3 |
| Description | cyclic nucleotide gated channel alpha 3 |
| Notes | This gene encodes a member of the cyclic nucleotide-gated cation channel protein family which is required for normal vision and olfactory signal transduction. Mutations in this gene are associated with achromatopsia (rod monochromacy) and color blindness. Two alternatively spliced transcripts encoding different isoforms have been described. [provided by RefSeq] |
| Ariadne Ontology | Non-voltage K+ efflux |
|---|---|
| Non-voltage Na+ influx |
| GO Molecular Function | nucleotide binding |
|---|---|
| cGMP binding | |
| signal transducer activity | |
| ion channel activity | |
| ligand-gated ion channel activity | |
| intracellular cyclic nucleotide activated cation channel activity | |
| intracellular cGMP activated cation channel activity |
| GO Cellular Component | membrane |
|---|---|
| integral to membrane | |
| plasma membrane | |
| photoreceptor outer segment |
| GO Biological Process | response to stimulus |
|---|---|
| transmembrane transport | |
| signal transduction | |
| retinal cone cell development | |
| ion transmembrane transport | |
| response to magnesium ion | |
| response to corticosteroid stimulus | |
| response to cAMP | |
| visual perception | |
| transport | |
| ion transport | |
| cation transport |
| Pathway | visual phototransduction pathway |
|---|---|
| altered visual phototransduction pathway |
| Group | Non-voltage K+ efflux |
|---|---|
| Non-voltage Na+ influx | |
| response to stimulus | |
| transmembrane transport | |
| signal transduction | |
| retinal cone cell development | |
| ion transmembrane transport | |
| response to magnesium ion | |
| response to corticosteroid stimulus | |
| response to cAMP | |
| visual perception | |
| transport | |
| ion transport | |
| cation transport | |
| nucleotide binding | |
| cGMP binding | |
| signal transducer activity | |
| ion channel activity | |
| ligand-gated ion channel activity | |
| intracellular cyclic nucleotide activated cation channel activity | |
| intracellular cGMP activated cation channel activity | |
| membrane | |
| integral to membrane | |
| plasma membrane | |
| photoreceptor outer segment |
| MedScan ID | 44 |
|---|
| Hugo ID | 2150 |
|---|
| Human chromosome position | 2q11.2 |
|---|
| LocusLink ID | 44 |
|---|---|
| 1261 | |
| 12790 | |
| 85257 |
| Alias | CNG3 |
|---|---|
| ACHM2 | |
| CCNC1 | |
| CCNCa | |
| CNCG3 | |
| CCNCalpha | |
| cyclic nucleotide-gated cation channel alpha-3 | |
| CNG-3 | |
| CNG channel alpha-3 | |
| cyclic nucleotide-gated channel alpha-3 | |
| cone photoreceptor cGMP-gated channel alpha subunit | |
| cone photoreceptor cGMP-gated channel subunit alpha | |
| cyclic nucleotide gated channel alpha 3 | |
| OTTHUMP00000161120 | |
| OTTMUSP00000029513 | |
| Cyclic nucleotide gated channel alpha III | |
| OTTHUMP00000203133 | |
| Cyclic-nucleotide-gated cation channel alpha III | |
| Cnga3 | |
| Cyclic-nucleotide-gated cation channel alpha 3 | |
| achromatopsia (rod monochromacy) 2 | |
| CCNC I | |
| CNG channel alpha 3 | |
| CNG channel alpha III |
| Organism | Homo sapiens |
|---|---|
| Mus musculus | |
| Rattus norvegicus |
| OMIM ID | 600053 |
|---|---|
| 216900 |
| Unigene ID | Hs.234785 |
|---|---|
| Mm.214224 | |
| Rn.10886 |
| KEGG ID | hsa:1261 |
|---|---|
| mmu:12790 | |
| rno:85257 |
| Swiss-Prot Accession | Q16281 |
|---|---|
| Q9JJZ8 | |
| Q9QWN7 | |
| Q8CFV6 | |
| Q9WV01 | |
| Q4VAP7 | |
| Q53RD2 | |
| Q9UP64 | |
| Q6ZNA7 | |
| P97627 | |
| Q9ER32 | |
| Q9ER33 | |
| Q9QX26 |
| GO ID | 0030553 |
|---|---|
| 0005221 | |
| 0015276 | |
| 0046549 | |
| 0007165 | |
| 0006810 | |
| 0007601 | |
| 0016021 | |
| 0001750 | |
| 0005886 | |
| 0005216 | |
| 0000166 | |
| 0006812 | |
| 0034220 | |
| 0006811 | |
| 0051591 | |
| 0032026 | |
| 0050896 | |
| 0055085 | |
| 0016020 | |
| 0005223 | |
| 0004871 | |
| 0031960 |
| PIR ID | I78560 |
|---|---|
| S74179 |
| Swiss-Prot ID | CNGA3_MOUSE |
|---|---|
| CNGA3_HUMAN | |
| Q4VAP7_HUMAN | |
| Q9QWN7_RAT | |
| Q8CFV6_MOUSE |
| Cell Localization | Membrane |
|---|---|
| Plasma membrane |
| IPI ID | IPI00122446 |
|---|---|
| IPI00000812 | |
| IPI00816511 | |
| IPI00190422 | |
| IPI00229409 | |
| IPI00442261 | |
| IPI00856786 | |
| IPI00780204 | |
| IPI00776808 | |
| IPI00777256 | |
| IPI00778973 | |
| IPI00781076 | |
| IPI00781859 |
| Mouse chromosome position | 1 |
|---|
| Rat chromosome position | 9q21 |
|---|
| Homologene ID | 994 |
|---|
| MGI ID | 1341818 |
|---|
| RGD ID | 70948 |
|---|
| Primary Cell Localization | Plasma membrane |
|---|