| URN | urn:agi-llid:5957 |
|---|---|
| Total Entities | 0 |
| Connectivity | 109 |
| Name | Rcvrn |
| Description | recoverin |
| Notes | This gene encodes a member of the recoverin family of neuronal calcium sensors. The encoded protein contains three calcium-binding EF-hand domains and may prolong the termination of the phototransduction cascade in the retina by blocking the phosphorylation of photo-activated rhodopsin. Recoverin may be the antigen responsible for cancer-associated retinopathy. [provided by RefSeq] |
| Ariadne Ontology | Secreted proteins |
|---|---|
| Biofluids assayable substances |
| GO Molecular Function | calcium ion binding |
|---|---|
| calcium sensitive guanylate cyclase activator activity |
| GO Cellular Component | dendrite |
|---|
| GO Biological Process | response to stimulus |
|---|---|
| signal transduction | |
| phototransduction | |
| regulation of calcium ion transport | |
| visual perception |
| Pathway | visual phototransduction pathway |
|---|---|
| altered visual phototransduction pathway |
| Group | response to stimulus |
|---|---|
| signal transduction | |
| phototransduction | |
| regulation of calcium ion transport | |
| visual perception | |
| calcium ion binding | |
| calcium sensitive guanylate cyclase activator activity | |
| dendrite | |
| Secreted proteins | |
| Biofluids assayable substances |
| MedScan ID | 5957 |
|---|
| Hugo ID | 9937 |
|---|
| Human chromosome position | 17p13.1 |
|---|
| LocusLink ID | 5957 |
|---|---|
| 19674 | |
| 140936 |
| Alias | RCV1 |
|---|---|
| recoverin | |
| cancer associated retinopathy antigen | |
| cancer-associated retinopathy protein | |
| CAR | |
| S-modulin | |
| RP23-338M9.3 | |
| guanylate cyclase activator | |
| cancer associated retinopathy protein | |
| 23 kDa photoreceptor cell-specific protein | |
| RCV I | |
| Rcvrn | |
| OTTMUSP00000006130 | |
| MGC129468 |
| Organism | Homo sapiens |
|---|---|
| Mus musculus | |
| Rattus norvegicus |
| OMIM ID | 179618 |
|---|
| Unigene ID | Hs.80539 |
|---|---|
| Mm.439726 | |
| Rn.38641 |
| KEGG ID | hsa:5957 |
|---|---|
| mmu:19674 | |
| rno:140936 |
| Swiss-Prot Accession | P35243 |
|---|---|
| Q53XL0 | |
| P34057 | |
| Q2TB46 | |
| Q8VH47 |
| GO ID | 0005509 |
|---|---|
| 0008048 | |
| 0007602 | |
| 0051924 | |
| 0007165 | |
| 0007601 | |
| 0050896 | |
| 0030425 |
| PIR ID | S21155 |
|---|---|
| JC1227 |
| Swiss-Prot ID | RECO_MOUSE |
|---|---|
| RECO_HUMAN | |
| Q8VH47_RAT | |
| Q53XL0_HUMAN | |
| Q2TB46_MOUSE |
| IPI ID | IPI00222363 |
|---|---|
| IPI00219720 | |
| IPI00206326 |
| Mouse chromosome position | 11 35.0 cM |
|---|
| Rat chromosome position | 10q24 |
|---|
| Homologene ID | 2177 |
|---|
| MGI ID | 97883 |
|---|
| RGD ID | 620258 |
|---|