| URN | urn:agi-llid:25769 |
|---|---|
| Total Entities | 0 |
| Connectivity | 20 |
| Name | Slc24a2 |
| Description | solute carrier family 24 (sodium/potassium/calcium exchanger), member 2 |
| Notes | The outer segment of retinal rod and cone photoreceptors contains electrogenic sodium-calcium exchangers which mediate a light-induced decrease in free calcium concentration. This function in cones is performed by SLC24A2 (Prinsen et al., 2000 [PubMed 10662833]).[supplied by OMIM] |
| Ariadne Ontology | Non-voltage K+ efflux |
|---|---|
| Na+ influx co-transport | |
| Ca++ export |
| GO Molecular Function | calcium channel activity |
|---|---|
| calcium, potassium:sodium antiporter activity | |
| antiporter activity | |
| symporter activity |
| GO Cellular Component | membrane |
|---|---|
| integral to membrane | |
| plasma membrane |
| GO Biological Process | transmembrane transport |
|---|---|
| long-term synaptic potentiation | |
| long term synaptic depression | |
| calcium ion transmembrane transport | |
| cellular calcium ion homeostasis | |
| learning | |
| memory | |
| visual perception | |
| ion transport | |
| sodium ion transport | |
| potassium ion transport | |
| calcium ion transport |
| Pathway | visual phototransduction pathway |
|---|---|
| altered visual phototransduction pathway |
| Group | Non-voltage K+ efflux |
|---|---|
| Na+ influx co-transport | |
| Ca++ export | |
| transmembrane transport | |
| long-term synaptic potentiation | |
| long term synaptic depression | |
| calcium ion transmembrane transport | |
| cellular calcium ion homeostasis | |
| learning | |
| memory | |
| visual perception | |
| ion transport | |
| sodium ion transport | |
| potassium ion transport | |
| calcium ion transport | |
| calcium channel activity | |
| calcium, potassium:sodium antiporter activity | |
| antiporter activity | |
| symporter activity | |
| membrane | |
| integral to membrane | |
| plasma membrane |
| MedScan ID | 25769 |
|---|
| Hugo ID | 10976 |
|---|
| Human chromosome position | 9p22.1 |
|---|---|
| 9p22-p13 |
| LocusLink ID | 25769 |
|---|---|
| 76376 | |
| 84550 |
| Alias | NCKX2 |
|---|---|
| sodium/potassium/calcium exchanger 2 | |
| retinal cone Na-Ca+K exchanger | |
| Na(+)/K(+)/Ca(2+)-exchange protein 2 | |
| AI847460 | |
| 2810021B17Rik | |
| 6330417K15Rik | |
| RP23-28B24.1 | |
| solute carrier family 24 (sodium/potassium/calcium exchanger), member 2 | |
| solute carrier family 24, member 2 | |
| potassium-dependent sodium-calcium exchanger | |
| OTTMUSP00000008100 | |
| Slc24a2 | |
| OTTMUSP00000008104 | |
| OTTMUSP00000008103 | |
| OTTHUMP00000021125 | |
| LOC100128844 | |
| 2810021B17 | |
| 6330417K15 | |
| OTTHUMP00000045115 | |
| FLJ45149 | |
| solute carrier family 24 member 2 |
| Organism | Homo sapiens |
|---|---|
| Mus musculus | |
| Rattus norvegicus |
| OMIM ID | 609838 |
|---|
| Unigene ID | Hs.283014 |
|---|---|
| Hs.590750 | |
| Hs.738749 | |
| Mm.490487 | |
| Rn.208755 | |
| Mm.127296 |
| KEGG ID | hsa:25769 |
|---|---|
| mmu:76376 | |
| rno:84550 |
| Swiss-Prot Accession | Q9UI40 |
|---|---|
| Q14BI1 | |
| Q8BUN9 | |
| O54701 | |
| B7ZLL8 | |
| Q9NTN5 | |
| Q9NZQ4 | |
| O54706 | |
| Q14AY1 | |
| Q3UWW4 | |
| Q8BYP4 | |
| Q8BZJ3 |
| GO ID | 0015297 |
|---|---|
| 0005262 | |
| 0015293 | |
| 0006874 | |
| 0006811 | |
| 0007612 | |
| 0060292 | |
| 0060291 | |
| 0007613 | |
| 0006813 | |
| 0006814 | |
| 0055085 | |
| 0007601 | |
| 0016021 | |
| 0005886 | |
| 0070588 | |
| 0006816 | |
| 0016020 | |
| 0008273 | |
| 0050896 | |
| 0005624 | |
| 0005509 | |
| 0030955 | |
| 0031402 |
| Swiss-Prot ID | NCKX2_HUMAN |
|---|---|
| NCKX2_RAT | |
| Q8BUN9_MOUSE | |
| Q14BI1_MOUSE |
| Cell Localization | Membrane |
|---|---|
| Plasma membrane |
| IPI ID | IPI00006444 |
|---|---|
| IPI00218809 | |
| IPI00197778 | |
| IPI00231428 | |
| IPI00225530 | |
| IPI00775867 | |
| IPI00884324 | |
| IPI00652257 | |
| IPI00406200 | |
| IPI00648345 | |
| IPI00648537 | |
| IPI00648825 |
| Mouse chromosome position | 4 |
|---|
| Rat chromosome position | 5q32 |
|---|
| Homologene ID | 10669 |
|---|
| MGI ID | 1923626 |
|---|
| RGD ID | 628650 |
|---|
| Primary Cell Localization | Plasma membrane |
|---|