| URN | urn:agi-llid:222962 |
|---|---|
| Total Entities | 0 |
| Connectivity | 52 |
| Name | Slc29a4 |
| Description | solute carrier family 29 (nucleoside transporters), member 4 |
| Notes | This gene is a member of the SLC29 family and encodes a plasma membrane protein with 11 transmembrane helices. This protein catalyzes the reuptake of monoamines into presynaptic neurons, thus determining the intensity and duration of monoamine neural signaling. It has been shown to transport several compounds, including serotonin, dopamine, and the neurotoxin 1-methyl-4-phenylpyridinium. Alternate transcriptional splice variants which encode the same protein have been characterized. [provided by RefSeq, Jul 2008] |
| Ariadne Ontology | Neurotransmitter uptake |
|---|---|
| Biofluids assayable substances |
| GO Molecular Function | nucleoside transmembrane transporter activity |
|---|
| GO Cellular Component | membrane |
|---|---|
| apical plasma membrane | |
| integral to membrane | |
| plasma membrane |
| GO Biological Process | transmembrane transport |
|---|---|
| transport | |
| nucleoside transport |
| Pathway | metformin pharmacokinetics pathway |
|---|
| Group | Neurotransmitter uptake |
|---|---|
| transmembrane transport | |
| transport | |
| nucleoside transport | |
| nucleoside transmembrane transporter activity | |
| membrane | |
| apical plasma membrane | |
| integral to membrane | |
| plasma membrane | |
| Biofluids assayable substances |
| MedScan ID | 222962 |
|---|
| Hugo ID | 23097 |
|---|
| Human chromosome position | 7p22.1 |
|---|
| LocusLink ID | 222962 |
|---|---|
| 243328 | |
| 288499 |
| Alias | ENT4 |
|---|---|
| PMAT | |
| PSEC0113 | |
| equilibrative nucleoside transporter 4 | |
| hENT4 | |
| solute carrier family 29 member 4 | |
| plasma membrane monoamine transporter | |
| mPMAT | |
| LOC381743 | |
| solute carrier family 29 (nucleoside transporters), member IV | |
| solute carrier family 29 (nucleoside transporters), member 4 | |
| Slc29a4 | |
| OTTHUMP00000025415 | |
| MGC38048 | |
| FLJ34923 | |
| equilibrative nucleoside transporter IV | |
| brain transport protein pmat |
| Organism | Homo sapiens |
|---|---|
| Mus musculus | |
| Rattus norvegicus |
| OMIM ID | 609149 |
|---|
| Unigene ID | Hs.4302 |
|---|---|
| Mm.125942 | |
| Rn.18610 |
| KEGG ID | hsa:222962 |
|---|---|
| mmu:243328 | |
| rno:288499 |
| Swiss-Prot Accession | Q7RTT9 |
|---|---|
| Q8R139 | |
| Q6PJ08 | |
| Q86WY8 | |
| Q8NAR3 | |
| Q8NBM2 |
| GO ID | 0005337 |
|---|---|
| 0055085 | |
| 0016324 | |
| 0016021 | |
| 0005886 | |
| 0006810 | |
| 0016020 | |
| 0015858 |
| Swiss-Prot ID | S29A4_MOUSE |
|---|---|
| S29A4_HUMAN |
| Cell Localization | Cell membrane |
|---|---|
| Apical cell membrane | |
| Plasma membrane |
| IPI ID | IPI00153278 |
|---|---|
| IPI00641511 | |
| IPI00888339 |
| Mouse chromosome position | 5 |
|---|
| Rat chromosome position | 12p11 |
|---|
| Homologene ID | 71345 |
|---|
| MGI ID | 2385330 |
|---|
| RGD ID | 1310545 |
|---|
| Primary Cell Localization | Plasma membrane |
|---|