Protein TP53BP1

URN	urn:agi-llid:7158
Total Entities	0
Connectivity	447
Name	TP53BP1
Description	tumor protein p53 binding protein 1

GO Molecular Function	RNA polymerase II transcription cofactor activity
	transcription factor binding
	p53 binding
	RNA polymerase II activating transcription factor binding
	methylated histone residue binding
	DNA binding
	damaged DNA binding
	telomeric DNA binding

GO Cellular Component	nucleoplasm
	replication fork
	chromosome, centromeric region
	kinetochore
	chromosome, telomeric region
	condensed chromosome kinetochore
	cytoplasm
	chromosome
	nucleus

GO Biological Process	DNA repair
	double-strand break repair
	double-strand break repair via homologous recombination
	cellular response to DNA damage stimulus
	positive regulation of transcription, DNA-templated
	positive regulation of transcription from RNA polymerase II promoter
	regulation of transcription, DNA-templated
	positive regulation of sequence-specific DNA binding transcription factor activity
	transcription, DNA-templated
	transcription from RNA polymerase II promoter

Pathway	Double Strand DNA Non-Homologous Repair
	Immunoglobulin Class-Switch Recombination via Alternative End-Joining
	Immunoglobulin Class-Switch Recombination via Classical Non-Homologous End-Joining
	ataxia telangiectasia-mutated (ATM) signaling pathway
	non-homologous end joining pathway of double-strand break repair
	Copy of 'ataxia telangiectasia-mutated (ATM) signaling pathway'

Group	Transcription factors
	DNA repair
	double-strand break repair
	double-strand break repair via homologous recombination
	cellular response to DNA damage stimulus
	positive regulation of transcription, DNA-templated
	positive regulation of transcription from RNA polymerase II promoter
	regulation of transcription, DNA-templated
	RNA polymerase II transcription cofactor activity
	positive regulation of sequence-specific DNA binding transcription factor activity
	transcription, DNA-templated
	transcription from RNA polymerase II promoter
	transcription factor binding
	p53 binding
	RNA polymerase II activating transcription factor binding
	methylated histone residue binding
	DNA binding
	damaged DNA binding
	telomeric DNA binding
	nucleoplasm
	replication fork
	chromosome, centromeric region
	kinetochore
	chromosome, telomeric region
	condensed chromosome kinetochore
	cytoplasm
	chromosome
	nucleus
	Basic Regulators of Immunoglobulin Class-Switch Recombination
	Basic Regulators of Alternative End Joining
	Secreted proteins

Alias	p202
	53BP1
	tumor suppressor p53-binding protein 1
	p53BP1
	p53-binding protein 1
	tumor protein 53-binding protein, 1
	tumor protein p53-binding protein, 1
	m53BP1
	Tp53bp1
	RP23-437L13.2
	murine p53-binding protein
	transformation related protein 53 binding-protein 1
	Trp53bp1
	transformation related protein 53 binding protein 1
	Tumor suppressor p53-binding protein I
	tumor protein p53 binding protein, I
	tumor protein p53 binding protein 1
	tumor protein 53-binding protein, I
	tumour 53-binding
	tumor 53-binding
	tumour suppressor p53-binding protein 1
	tumor p53 binding
	tumour p53 binding
	tumour protein 53-binding protein, 1
	tumour protein 53-binding protein, I
	tumour protein p53 binding protein, I
	tumour suppressor p53-binding protein I
	LOC100502715
	TP53BP I
	tumour protein p53 binding protein 1
	m53BP I
	53BP I
	LOC688035
	Trp53bp I
	MGC100303
	MGC138366
	OTTMUSP00000017048
	P531_HUMAN
	p53-binding protein I
	transformation related protein 53 binding protein I
	OTTMUSP00000017066
	FLJ41424

Mouse chromosome position	2

OMIM ID	605230

Rat chromosome position	3q35

Hugo ID	11999

Human chromosome position	15q15-q21

PIR ID	I38604

Swiss-Prot ID	TP53B_HUMAN
	TP53B_MOUSE

Homologene ID	4137

MGI ID	1351320

RGD ID	1308039

MedScan ID	7158

Primary Cell Localization	Nucleus