| URN | urn:agi-llid:8865 |
|---|---|
| Total Entities | 0 |
| Connectivity | 47 |
| Name | Baz1b |
| Description | bromodomain adjacent to zinc finger domain, 1B |
| Notes | This gene encodes a member of the bromodomain protein family. The bromodomain is a structural motif characteristic of proteins involved in chromatin-dependent regulation of transcription. This gene is deleted in Williams-Beuren syndrome, a developmental disorder caused by deletion of multiple genes at 7q11.23. [provided by RefSeq, Jul 2008] |
| GO Molecular Function | chromatin binding |
|---|---|
| protein complex scaffold | |
| histone binding | |
| vitamin D receptor binding | |
| histone acetyl-lysine binding | |
| nucleotide binding | |
| ATP binding | |
| metal ion binding | |
| zinc ion binding | |
| transferase activity | |
| kinase activity | |
| histone kinase activity | |
| protein tyrosine kinase activity | |
| non-membrane spanning protein tyrosine kinase activity | |
| vitamin D receptor activator activity |
| GO Cellular Component | chromatin remodeling complex |
|---|---|
| WINAC complex | |
| nuclear replication fork | |
| centromeric heterochromatin | |
| condensed chromosome | |
| nucleus |
| GO Biological Process | chromatin-mediated maintenance of transcription |
|---|---|
| regulation of transcription, DNA-dependent | |
| transcription, DNA-dependent | |
| double-strand break repair | |
| protein phosphorylation | |
| histone phosphorylation | |
| phosphorylation | |
| response to DNA damage stimulus | |
| nucleosome disassembly | |
| DNA replication-dependent nucleosome disassembly | |
| chromatin assembly or disassembly | |
| chromatin remodeling | |
| ATP-dependent chromatin remodeling | |
| regulation of gene expression, epigenetic | |
| heart morphogenesis |
| Pathway | ataxia telangiectasia-mutated (ATM) signaling pathway |
|---|
| Group | chromatin-mediated maintenance of transcription |
|---|---|
| regulation of transcription, DNA-dependent | |
| transcription, DNA-dependent | |
| double-strand break repair | |
| protein phosphorylation | |
| histone phosphorylation | |
| phosphorylation | |
| response to DNA damage stimulus | |
| nucleosome disassembly | |
| DNA replication-dependent nucleosome disassembly | |
| chromatin assembly or disassembly | |
| chromatin remodeling | |
| ATP-dependent chromatin remodeling | |
| regulation of gene expression, epigenetic | |
| heart morphogenesis | |
| chromatin binding | |
| protein complex scaffold | |
| histone binding | |
| vitamin D receptor binding | |
| histone acetyl-lysine binding | |
| nucleotide binding | |
| ATP binding | |
| metal ion binding | |
| zinc ion binding | |
| transferase activity | |
| kinase activity | |
| histone kinase activity | |
| protein tyrosine kinase activity | |
| non-membrane spanning protein tyrosine kinase activity | |
| vitamin D receptor activator activity | |
| chromatin remodeling complex | |
| WINAC complex | |
| nuclear replication fork | |
| centromeric heterochromatin | |
| condensed chromosome | |
| nucleus |
| MedScan ID | 8865 |
|---|
| Hugo ID | 961 |
|---|
| Human chromosome position | 7q11.23 |
|---|
| LocusLink ID | 8865 |
|---|---|
| 9031 | |
| 22385 | |
| 368002 |
| Alias | WSTF |
|---|---|
| WBSCR9 | |
| WBSCR10 | |
| tyrosine-protein kinase BAZ1B | |
| hWALp2 | |
| transcription factor WSTF | |
| williams syndrome transcription factor | |
| williams-Beuren syndrome chromosomal region 9 protein | |
| williams-Beuren syndrome chromosomal region 10 protein | |
| C87820 | |
| williams syndrome transcription factor homolog | |
| Williams-Beuren syndrome chromosome region 9 homolog | |
| bromodomain adjacent to zinc finger domain protein 1B | |
| williams-Beuren syndrome chromosomal region 9 protein homolog | |
| bromodomain adjacent to zinc finger domain, 1B; Williams-Beuren syndrome chromosome region 9 homolog | |
| Williams-Beuren syndrome chromosome region 10 | |
| Williams-Beuren syndrome chromosome region 9 | |
| williams-beuren syndrome chromosome region 9 homolog (human) | |
| OTTHUMP00000197535 | |
| bromodomain adjacent to zinc finger domain, 1B; Williams-Beuren syndrome chromosome region 9 homolog (human) | |
| Baz1b | |
| LOC194311 | |
| LOC231781 | |
| OTTMUSP00000018605 |
| Organism | Homo sapiens |
|---|---|
| Mus musculus | |
| Rattus norvegicus |
| OMIM ID | 605681 |
|---|
| Unigene ID | Hs.647016 |
|---|---|
| Mm.40331 | |
| Rn.7043 |
| KEGG ID | hsa:9031 |
|---|---|
| mmu:22385 | |
| rno:368002 |
| Swiss-Prot Accession | Q9UIG0 |
|---|---|
| Q9Z277 | |
| G3V661 | |
| B9EJ99 | |
| Q3URP5 | |
| Q3USR7 | |
| Q3UVM2 | |
| Q8CAU9 | |
| Q9CU68 | |
| B9EGK3 | |
| D3DXE9 | |
| O95039 | |
| O95247 | |
| O95277 | |
| Q6P1K4 | |
| Q86UJ6 |
| EC Number | 2.7.10.2 |
|---|
| GO ID | 0005524 |
|---|---|
| 0003682 | |
| 0070577 | |
| 0035173 | |
| 0004715 | |
| 0032947 | |
| 0004713 | |
| 0071884 | |
| 0042809 | |
| 0008270 | |
| 0043044 | |
| 0034725 | |
| 0048096 | |
| 0006302 | |
| 0003007 | |
| 0016572 | |
| 0006337 | |
| 0040029 | |
| 0006355 | |
| 0006974 | |
| 0006351 | |
| 0071778 | |
| 0005721 | |
| 0016585 | |
| 0000793 | |
| 0043596 | |
| 0042393 | |
| 0016301 | |
| 0046872 | |
| 0000166 | |
| 0016740 | |
| 0006333 | |
| 0006338 | |
| 0016310 | |
| 0006468 | |
| 0005634 |
| PIR ID | T17401 |
|---|
| Swiss-Prot ID | BAZ1B_MOUSE |
|---|---|
| BAZ1B_HUMAN |
| Cell Localization | Nucleus |
|---|
| IPI ID | IPI00923656 |
|---|---|
| IPI00930843 | |
| IPI00069817 | |
| IPI00216695 |
| Mouse chromosome position | 5 |
|---|
| Rat chromosome position | 12q12 |
|---|
| Homologene ID | 22651 |
|---|
| MGI ID | 1353499 |
|---|
| RGD ID | 1597089 |
|---|