| URN | urn:agi-Regulation:inout-urn:agi-llid:1162:out-urn:agi-meshdis:Cockayne%20Syndrome::unknown |
|---|---|
| References | 4 |
| Connectivity | 2 |
| Effect | unknown |
| Original # of References | 4 |
| TextRef | info:pmid/17854076#abs:2 |
|---|---|
| PubYear | 2008 |
| MedlineTA | Hum Mutat |
| MedLine Reference | 17854076:1 |
| Sentence | However, the Cockayne syndrome caused by the ERCC6 defect has not been linked to cancer predisposition; likely due to the fact that cells with severe disruption of the ERCC6 function are sensitive to lesion-induced apoptosis, thus reducing the chance of tumorigenesis. |
| TextRef | info:pmid/19894250#title:1 |
|---|---|
| PubYear | 2010 |
| MedLine Reference | 19894250:100 |
| Sentence | Mutation update for the CSB/ERCC6 and CSA/ERCC8 genes involved in Cockayne syndrome. |
| TextRef | info:pmid/15489290#body:317 |
|---|---|
| PubYear | 2004 |
| MedlineTA | Genes Dev |
| MedLine Reference | 15489290:1316 |
| Sentence | Mutations in the CSA and CSB/ERCC6 genes result in Cockayne Syndrome , a premature-aging syndrome that is characterized by developmental abnormalities. |
| TextMods | 69: '(CS)' -> '' |
| TextRef | info:pmid/15226310#body:279 |
|---|---|
| PubYear | 2004 |
| MedlineTA | J Cell Biol |
| MedLine Reference | 15226310:1278 |
| Sentence | When a complex is stalled on a DNA lesion the transient interactions of the Cockayne syndrome B protein are stabilized, to allow Cockayne syndrome B to exert its function in damage removal. |
| TextMods | 76: 'CSB ' -> 'Cockayne syndrome B ' 129: 'CSB ' -> 'Cockayne syndrome B ' |