| URN | urn:agi-llid:169355 |
|---|---|
| Total Entities | 0 |
| Connectivity | 41 |
| Name | Ido2 |
| Description | indoleamine 2,3-dioxygenase 2 |
| Notes | Along with the enzymes encoded by the INDO (MIM 147435) and TDO2 (MIM 191070) genes, the enzyme encoded by the INDOL1 gene metabolizes tryptophan in the kynurenine pathway (Ball et al., 2007 [PubMed 17499941]).[supplied by OMIM, Feb 2011] |
| GO Molecular Function | oxidoreductase activity |
|---|---|
| dioxygenase activity | |
| tryptophan 2,3-dioxygenase activity | |
| indoleamine 2,3-dioxygenase activity | |
| heme binding | |
| metal ion binding |
| GO Cellular Component | cytoplasm |
|---|---|
| cytosol |
| GO Biological Process | small molecule metabolic process |
|---|---|
| oxidation-reduction process | |
| tryptophan catabolic process | |
| tryptophan catabolic process to kynurenine | |
| cellular nitrogen compound metabolic process |
| Pathway | kynurenine metabolic pathway |
|---|
| Group | small molecule metabolic process |
|---|---|
| oxidation-reduction process | |
| tryptophan catabolic process | |
| tryptophan catabolic process to kynurenine | |
| oxidoreductase activity | |
| dioxygenase activity | |
| tryptophan 2,3-dioxygenase activity | |
| indoleamine 2,3-dioxygenase activity | |
| cellular nitrogen compound metabolic process | |
| heme binding | |
| metal ion binding | |
| cytoplasm | |
| cytosol |
| LocusLink ID | 169355 |
|---|---|
| 209176 | |
| 681319 |
| GO ID | 0020037 |
|---|---|
| 0033754 | |
| 0046872 | |
| 0004833 | |
| 0034641 | |
| 0044281 | |
| 0006569 | |
| 0019441 | |
| 0005737 | |
| 0005829 | |
| 0051213 | |
| 0016491 | |
| 0055114 |
| Alias | INDOL1 |
|---|---|
| indoleamine 2,3-dioxygenase 2 | |
| IDO-2 | |
| indoleamine 2,3-dioxygenase-like 1 protein | |
| indoleamine 2,3-dioxygenase-like protein 1 | |
| indoleamine-pyrrole 2,3 dioxygenase-like 1 | |
| indoleamine-pyrrole 2,3-dioxygenase-like protein 1 | |
| AI265623 | |
| C230043N17Rik | |
| C230043N17 | |
| IDO2 | |
| OTTHUMP00000223617 | |
| OTTMUSP00000038470 | |
| LOC684861 | |
| LOC169355 |
| Mouse chromosome position | 8 |
|---|
| OMIM ID | 612129 |
|---|
| Rat chromosome position | 16q12.5 |
|---|
| Hugo ID | 27269 |
|---|
| Human chromosome position | 8p11.21 |
|---|
| Swiss-Prot Accession | F5H5G0 |
|---|---|
| Q6ZQW0 | |
| A4UHF3 | |
| Q8R0V5 | |
| A4UD41 |
| Unigene ID | Hs.676257 |
|---|---|
| Mm.219580 |
| KEGG ID | hsa:169355 |
|---|---|
| mmu:209176 | |
| rno:681319 |
| Swiss-Prot ID | I23O2_HUMAN |
|---|
| EC Number | 1.13.11.52 |
|---|---|
| 1.13.11.- |
| Ensembl ID | ENSG00000188676 |
|---|---|
| ENSP00000443432 | |
| ENST00000502986 | |
| ENSMUSG00000031549 | |
| ENSMUSP00000033953 | |
| ENSMUST00000033953 |
| Homologene ID | 48830 |
|---|
| Organism | Homo sapiens |
|---|---|
| Mus musculus | |
| Rattus norvegicus |
| MGI ID | 2142489 |
|---|
| RGD ID | 1596771 |
|---|
| MedScan ID | 169355 |
|---|