Protein Cbr1

URN urn:agi-llid:873
Total Entities 0
Connectivity 179
Name Cbr1
Description carbonyl reductase 1
Notes Carbonyl reductase is one of several monomeric, NADPH-dependent oxidoreductases having wide specificity for carbonyl compounds. This enzyme is widely distributed in human tissues. Another carbonyl reductase gene, CRB3, lies close to this gene on chromosome 21q. [provided by RefSeq, Jul 2008]
Ariadne Ontology Prostaglandins, Thromboxane synthesis
Secreted proteins
Biofluids assayable substances
GO Molecular Function nucleotide binding
oxidoreductase activity
oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor
prostaglandin-E2 9-reductase activity
15-hydroxyprostaglandin dehydrogenase (NADP+) activity
carbonyl reductase (NADPH) activity
GO Cellular Component plasma membrane
cytoplasm
cytosol
intracellular membrane-bounded organelle
nucleus
microvillus
GO Biological Process metabolic process
drug metabolic process
peptidyl-lysine modification
vitamin K metabolic process
phylloquinone catabolic process
response to lipopolysaccharide
response to gonadotropin stimulus
response to testosterone stimulus
ovulation from ovarian follicle
oxidation-reduction process
Pathway prostanoid biosynthetic pathway
Group Prostaglandins, Thromboxane synthesis
metabolic process
drug metabolic process
peptidyl-lysine modification
vitamin K metabolic process
phylloquinone catabolic process
response to lipopolysaccharide
response to gonadotropin stimulus
response to testosterone stimulus
ovulation from ovarian follicle
oxidation-reduction process
nucleotide binding
oxidoreductase activity
oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor
prostaglandin-E2 9-reductase activity
15-hydroxyprostaglandin dehydrogenase (NADP+) activity
carbonyl reductase (NADPH) activity
plasma membrane
cytoplasm
cytosol
intracellular membrane-bounded organelle
nucleus
microvillus
Secreted proteins
Biofluids assayable substances
MedScan ID 873
649801
Hugo ID 1548
Human chromosome position 21q22.13
GenBank ID NC_000021
NM_001757
NP_001748
NC_018932
AC_000153
AB003151
BAA33498
AP000688
AP001724
BAA95508
CH471079
EAX09752
EAX09753
EAX09754
EAX09755
EF141836
ABK97430
M62420
AAA17881
AB124848
BAE45940
AK294142
BAG57468
AK308691
AK311219
AK314879
BAG37394
AL548852
BC002511
AAH02511
BC015640
AAH15640
BT019843
AAV38646
CR541708
CAG46509
J04056
AAA52070
P16152
DQ892353
ABM83279
DQ895559
ABM86485
NC_000082
NM_007620
NP_031646
AC_000038
AC160993
CH466602
EDL03764
EDL03765
AK146805
BC012714
AAH12714
BC158026
AAI58027
BC158029
AAI58030
BY319589
BY635597
U31966
AAB19006
P48758
NC_005110
NM_019170
NP_062043
NW_001089764
CH473989
EDM10787
D89070
BAA19008
X95986
CAA65230
AF023086
AAB81080
AF181955
AAF03394
AF181956
AAF03395
AF181957
AAF03396
BC105893
AAI05894
D89069
BAA19007
X84349
CAA59088
P47727
XM_003751016
XP_003751064
AABR06067713
LocusLink ID 873
12408
29224
100360507
Alias CBR
hCBR1
SDR21C1
carbonyl reductase [NADPH] 1
carbonyl reductase (NADPH) 1
prostaglandin 9-ketoreductase
prostaglandin-E(2) 9-reductase
NADPH-dependent carbonyl reductase 1
15-hydroxyprostaglandin dehydrogenase
short chain dehydrogenase/reductase family 21C, member 1
CR
AW261796
Carbonyl reductase [NADPH] 1 (NADPH-dependent carbonyl reductase 1)
Cbr 1
20-beta-hydroxysteroid dehydrogenase
inducible carbonyl reductase-like
CRN
NADP-dependent 15-hydroxyprostaglandin dehydrogenases
nonspecific NADPH-dependent carbonyl reductase
nonspecific NADP(H)-dependent carbonyl reductase
nonspecific NAD(P)H-dependent carbonyl reductase
NADP-specific 15-hydroxyprostaglandin dehydrogenases
NADP-specific 15-hydroxyprostaglandin dehydrogenase
NADP-linked 15-hydroxyprostaglandin dehydrogenases
NADP-linked 15-hydroxyprostaglandin dehydrogenase
NADPH-dependent carbonyl reductase I
NADP(H)-dependent carbonyl reductase 1
NADPH2-dependent carbonyl reductase
OTTMUSP00000021476
NADP-dependent 15-hydroxyprostaglandin dehydrogenase
NADP(H)-dependent carbonyl reductase I
prostaglandin E2-9-oxoreductases
NADP(H)2-dependent carbonyl reductase
type II 15-hydroxyprostaglandin dehydrogenase
xenobiotic ketone reductase
type II 15-hydroxyprostaglandin dehydrogenases
PGE2 9-oxoreductase
prostaglandin E2-9-oxoreductase
prostaglandin E 9-ketoreductase
PGE-9-ketoreductase
PGE2-9-OR
PGE2-9-ketoreductase
reductase, 15-hydroxy-9-oxoprostaglandin
carbonyl reductase (NAD(P)H) 1
NAD(P)H-dependent carbonyl reductase I
15-hydroxyprostaglandin dehydrogenase (NADP)
15-hydroxyprostaglandin dehydrogenase (NADP+)
15-hydroxyprostaglandin dehydrogenases
9-keto-prostaglandin E2 reductase
9-ketoprostaglandin reductase
ALR3
carbonyl reductase (NAD(P)H)
carbonyl reductase (NAD(P)H) I
carbonyl reductase (NADP(H))
carbonyl reductase (NADP(H)) 1
carbonyl reductase (NADP(H)) I
carbonyl reductase (NADPH)
LOC224441
NAD(P)H-dependent carbonyl reductase 1
MGC124927
carbonyl reductase (NADPH) I
CBR1
carbonyl reductase I
carbonyl reductase 1
Carbonyl reductase [NADP(H)] 1 (NADP(H)-dependent carbonyl reductase 1)
Carbonyl reductase [NAD(P)H] 1 (NAD(P)H-dependent carbonyl reductase 1)
carbonyl reductase 2 (Cricetulus griseus)
NAD(P)H2-dependent carbonyl reductase
LOC100360507
Organism Homo sapiens
Mus musculus
Rattus norvegicus
OMIM ID 114830
Unigene ID Hs.88778
Mm.26940
Rn.3425
KEGG ID hsa:873
mmu:12408
rno:29224
rno:100360507
Swiss-Prot Accession P16152
B2RXY7
P48758
P47727
B2RBZ7
Q3LHW8
Q91X28
O08558
Q3KR58
EC Number 1.1.1.197
1.1.1.184
1.1.1.189
GO ID 0047021
0004090
0000166
0016655
0050221
0017144
0055114
0042373
0005737
0016491
0008152
0042376
0043231
0005902
0005634
0005886
0001542
0018205
0034698
0032496
0033574
0005829
PIR ID A61271
S68982
Swiss-Prot ID CBR1_HUMAN
CBR1_MOUSE
CBR1_RAT
Cell Localization Cytoplasm
Plasma membrane
IPI ID IPI00295386
IPI00314191
IPI00331856
Mouse chromosome position 16 67.0 cM
Rat chromosome position 11q11
11
MGI ID 88284
RGD ID 2286
2321950
Primary Cell Localization Plasma membrane