| URN | urn:agi-llid:10327 |
|---|---|
| Total Entities | 0 |
| Connectivity | 45 |
| Name | Akr1a1 |
| Description | aldo-keto reductase family 1, member A1 (aldehyde reductase) |
| Notes | This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member, also known as aldehyde reductase, is involved in the reduction of biogenic and xenobiotic aldehydes and is present in virtually every tissue. Multiple alternatively spliced transcript variants of this gene exist, all encoding the same protein. [provided by RefSeq, Jan 2011] |
| Ariadne Ontology | Glucose metabolism |
|---|
| GO Molecular Function | electron carrier activity |
|---|---|
| oxidoreductase activity | |
| L-glucuronate reductase activity | |
| alcohol dehydrogenase (NADP+) activity | |
| alditol:NADP+ 1-oxidoreductase activity |
| GO Cellular Component | apical plasma membrane |
|---|---|
| cytosol |
| GO Biological Process | cellular aldehyde metabolic process |
|---|---|
| aldehyde catabolic process | |
| L-ascorbic acid biosynthetic process | |
| D-glucuronate catabolic process | |
| glucose metabolic process | |
| oxidation-reduction process |
| Pathway | prostanoid biosynthetic pathway |
|---|
| Group | Glucose metabolism |
|---|---|
| cellular aldehyde metabolic process | |
| aldehyde catabolic process | |
| L-ascorbic acid biosynthetic process | |
| D-glucuronate catabolic process | |
| glucose metabolic process | |
| oxidation-reduction process | |
| electron carrier activity | |
| oxidoreductase activity | |
| L-glucuronate reductase activity | |
| alcohol dehydrogenase (NADP+) activity | |
| alditol:NADP+ 1-oxidoreductase activity | |
| apical plasma membrane | |
| cytosol |
| MedScan ID | 10327 |
|---|
| Hugo ID | 380 |
|---|
| Human chromosome position | 1p33-p32 |
|---|
| LocusLink ID | 10327 |
|---|---|
| 58810 | |
| 78959 |
| Alias | ALR |
|---|---|
| ARM | |
| DD3 | |
| ALDR1 | |
| RP4-697E16.2 | |
| alcohol dehydrogenase [NADP(+)] | |
| aldehyde reductase | |
| alcohol dehydrogenase | |
| dihydrodiol dehydrogenase 3 | |
| aldo-keto reductase family 1 member A1 | |
| Akr1a4 | |
| 2610201A18Rik | |
| RP23-177C18.1 | |
| aldo-keto reductase family 1, member A4 (aldehyde reductase) | |
| 3-DG-reducing enzyme | |
| aldo-keto reductase family 1, member a4 | |
| OTTMUSP00000009953 | |
| OTTHUMP00000009241 | |
| OTTHUMP00000009240 | |
| MGC1380 | |
| MGC12529 | |
| aldo-keto reductase family 1, member A1 (aldehyde reductase) | |
| aldo-keto reductase family 1, member A1 | |
| aldehyde reductase (Cricetulus griseus) | |
| Akr1a1 | |
| Akr1a I | |
| 2610201A18Rik(2) | |
| 2610201A18 |
| Organism | Homo sapiens |
|---|---|
| Mus musculus | |
| Rattus norvegicus |
| OMIM ID | 103830 |
|---|
| Unigene ID | Hs.474584 |
|---|---|
| Hs.721160 | |
| Mm.30085 | |
| Rn.835 |
| KEGG ID | hsa:10327 |
|---|---|
| mmu:58810 | |
| rno:78959 |
| Swiss-Prot Accession | P14550 |
|---|---|
| Q540D7 | |
| Q80XJ7 | |
| Q9JII6 | |
| P51635 | |
| Q9CQI5 | |
| Q9CQT8 | |
| Q9CT53 | |
| Q9D012 | |
| Q9D016 | |
| Q9D0I7 | |
| Q9D0P3 | |
| A8KAL8 | |
| D3DQ04 | |
| Q6IAZ4 |
| EC Number | 1.1.1.2 |
|---|
| GO ID | 0047939 |
|---|---|
| 0004032 | |
| 0009055 | |
| 0042840 | |
| 0019853 | |
| 0046185 | |
| 0006081 | |
| 0006006 | |
| 0016324 | |
| 0005829 | |
| 0008106 | |
| 0016491 | |
| 0055114 |
| PIR ID | A33851 |
|---|---|
| JN0629 |
| Swiss-Prot ID | AK1A1_MOUSE |
|---|---|
| AK1A1_HUMAN | |
| AK1A1_RAT |
| Cell Localization | Cytoplasm |
|---|
| IPI ID | IPI00466128 |
|---|---|
| IPI00220271 | |
| IPI00230859 |
| Mouse chromosome position | 4 |
|---|
| Rat chromosome position | 5q36 |
|---|
| Homologene ID | 74565 |
|---|
| MGI ID | 1929955 |
|---|
| RGD ID | 68346 |
|---|
| Primary Cell Localization | Cytoplasm |
|---|