| URN | urn:agi-llid:50592 |
|---|---|
| Connectivity | 2 |
| Name | Gria1 |
| Description | glutamate receptor, ionotropic, AMPA 1 |
| Notes | mouse homolog may play a role in regulation of neuronal synaptic plasticity and conditioned reinforcement learning [RGD] |
| Pathway | calcium/calmodulin dependent kinase 2 signaling pathway |
|---|---|
| calcium-calmodulin dependent kinase 2 signaling pathway |
| GO Molecular Function | protein domain specific binding |
|---|---|
| protein homodimerization activity | |
| PDZ domain binding | |
| small GTPase binding | |
| protein kinase binding | |
| myosin V binding | |
| receptor activity | |
| ionotropic glutamate receptor activity | |
| ion channel activity | |
| extracellular-glutamate-gated ion channel activity |
| GO Cellular Component | synapse |
|---|---|
| protein complex | |
| postsynaptic membrane | |
| postsynaptic density | |
| asymmetric synapse | |
| plasma membrane | |
| neuronal cell body | |
| dendritic spine | |
| dendritic shaft | |
| endoplasmic reticulum membrane | |
| endoplasmic reticulum | |
| early endosome | |
| endocytic vesicle membrane | |
| synaptosome | |
| ionotropic glutamate receptor complex | |
| cell junction | |
| integral to membrane |
| GO Biological Process | spinal cord development |
|---|---|
| positive regulation of synaptic transmission | |
| regulation of synaptic transmission | |
| regulation of synaptic plasticity | |
| synaptic transmission, glutamatergic | |
| regulation of receptor recycling | |
| receptor internalization | |
| regulation of action potential in neuron | |
| cellular response to growth factor stimulus | |
| cellular response to dsRNA | |
| response to fungicide | |
| response to lithium ion | |
| ion transport |
| Group | synapse |
|---|---|
| spinal cord development | |
| positive regulation of synaptic transmission | |
| regulation of synaptic transmission | |
| regulation of synaptic plasticity | |
| synaptic transmission, glutamatergic | |
| regulation of receptor recycling | |
| receptor internalization | |
| regulation of action potential in neuron | |
| cellular response to growth factor stimulus | |
| cellular response to dsRNA | |
| response to fungicide | |
| response to lithium ion | |
| ion transport | |
| protein domain specific binding | |
| protein homodimerization activity | |
| PDZ domain binding | |
| small GTPase binding | |
| protein kinase binding | |
| myosin V binding | |
| receptor activity | |
| ionotropic glutamate receptor activity | |
| ion channel activity | |
| extracellular-glutamate-gated ion channel activity | |
| protein complex | |
| postsynaptic membrane | |
| postsynaptic density | |
| asymmetric synapse | |
| plasma membrane | |
| neuronal cell body | |
| dendritic spine | |
| dendritic shaft | |
| endoplasmic reticulum membrane | |
| endoplasmic reticulum | |
| early endosome | |
| endocytic vesicle membrane | |
| synaptosome | |
| ionotropic glutamate receptor complex | |
| cell junction | |
| integral to membrane |
| MedScan ID | 50592 |
|---|
| LocusLink ID | 50592 |
|---|
| Alias | GluA1 |
|---|---|
| gluR-A | |
| glutamate receptor 1 | |
| gluR-1 | |
| gluR-K1 | |
| glutamate receptor A | |
| glutamate receptor subunit GluR1 | |
| AMPA-selective glutamate receptor 1 | |
| glutamate receptor, ionotropic, AMPA1 (alpha 1) | |
| Glur1 | |
| LOC691178 |
| Organism | Rattus norvegicus |
|---|
| GO ID | 0030165 |
|---|---|
| 0005234 | |
| 0005216 | |
| 0004970 | |
| 0031489 | |
| 0019904 | |
| 0042803 | |
| 0019901 | |
| 0004872 | |
| 0031267 | |
| 0071359 | |
| 0071363 | |
| 0006811 | |
| 0050806 | |
| 0031623 | |
| 0019228 | |
| 0001919 | |
| 0048167 | |
| 0050804 | |
| 0060992 | |
| 0010226 | |
| 0021510 | |
| 0035249 | |
| 0032279 | |
| 0030054 | |
| 0043198 | |
| 0043197 | |
| 0005769 | |
| 0030666 | |
| 0005783 | |
| 0005789 | |
| 0016021 | |
| 0008328 | |
| 0043025 | |
| 0005886 | |
| 0014069 | |
| 0045211 | |
| 0043234 | |
| 0045202 | |
| 0019717 |
| Rat chromosome position | 10 |
|---|
| Swiss-Prot Accession | P19490 |
|---|---|
| Q924I5 | |
| Q9QXM7 |
| PIR ID | A40170 |
|---|---|
| S07059 |
| Unigene ID | Rn.29971 |
|---|
| KEGG ID | rno:50592 |
|---|
| Swiss-Prot ID | GRIA1_RAT |
|---|
| Cell Localization | Cell membrane |
|---|---|
| Endoplasmic reticulum membrane | |
| Cell junction | |
| synapse | |
| postsynaptic cell membrane |
| IPI ID | IPI00231012 |
|---|---|
| IPI00324555 | |
| IPI00882436 | |
| IPI00768980 |
| RGD ID | 621531 |
|---|