| URN | urn:agi-llid:10369 |
|---|---|
| Connectivity | 62 |
| Name | Cacng2 |
| Description | calcium channel, voltage-dependent, gamma subunit 2 |
| Notes | L-type calcium channels are composed of five subunits. The protein encoded by this gene represents one of these subunits, gamma, and is one of several gamma subunit proteins. It is an integral membrane protein that is thought to stabilize the calcium channel in an inactive (closed) state. This protein is similar to the mouse stargazin protein, mutations in which have been associated with absence seizures, also known as petit-mal or spike-wave seizures. This gene is a member of the neuronal calcium channel gamma subunit gene subfamily of the PMP-22/EMP/MP20 family. [provided by RefSeq] |
| Pathway | calcium/calmodulin dependent kinase 2 signaling pathway |
|---|---|
| calcium-calmodulin dependent kinase 2 signaling pathway |
| GO Molecular Function | calcium channel regulator activity |
|---|---|
| ionotropic glutamate receptor binding | |
| calcium ion binding | |
| ion channel activity | |
| voltage-gated ion channel activity | |
| calcium channel activity | |
| voltage-gated calcium channel activity |
| GO Cellular Component | membrane |
|---|---|
| plasma membrane | |
| endocytic vesicle membrane | |
| voltage-gated calcium channel complex | |
| integral to membrane |
| GO Biological Process | transport |
|---|---|
| neurological system process | |
| transmission of nerve impulse | |
| regulation of membrane potential | |
| membrane depolarization | |
| membrane hyperpolarization | |
| neuromuscular junction development | |
| ion transport | |
| calcium ion transport |
| Ariadne Ontology | Voltage-dependent Ca++ import |
|---|---|
| Tight junction assembly |
| Group | Voltage-dependent Ca++ import |
|---|---|
| Tight junction assembly | |
| transport | |
| neurological system process | |
| transmission of nerve impulse | |
| regulation of membrane potential | |
| membrane depolarization | |
| membrane hyperpolarization | |
| neuromuscular junction development | |
| ion transport | |
| calcium ion transport | |
| calcium channel regulator activity | |
| ionotropic glutamate receptor binding | |
| calcium ion binding | |
| ion channel activity | |
| voltage-gated ion channel activity | |
| calcium channel activity | |
| voltage-gated calcium channel activity | |
| membrane | |
| plasma membrane | |
| endocytic vesicle membrane | |
| voltage-gated calcium channel complex | |
| integral to membrane |
| MedScan ID | 10369 |
|---|
| Hugo ID | 1406 |
|---|
| Human chromosome position | 22q13.1 |
|---|
| LocusLink ID | 10369 |
|---|---|
| 12300 | |
| 84347 |
| Alias | MGC138502 |
|---|---|
| MGC138504 | |
| voltage-dependent calcium channel gamma-2 subunit | |
| stargazin | |
| neuronal voltage-gated calcium channel gamma-2 subunit | |
| stg | |
| wag | |
| waggler | |
| AW060990 | |
| MGC123981 | |
| stargazer | |
| B230105C07Rik | |
| B930041E13Rik | |
| AL589650.1 | |
| TARP gamma 2 | |
| OTTMUSP00000017670 | |
| Ipr328 | |
| B230105C07 | |
| B930041E13 | |
| Cacng2 | |
| calcium channel, voltage-dependent, gamma subunit 2 | |
| calcium channel, voltage-dependent, gamma subunit II | |
| wagglers |
| Organism | Homo sapiens |
|---|---|
| Mus musculus | |
| Rattus norvegicus |
| OMIM ID | 602911 |
|---|
| Mouse chromosome position | 15 45.2 cM |
|---|
| GO ID | 0035255 |
|---|---|
| 0005245 | |
| 0005244 | |
| 0006816 | |
| 0006811 | |
| 0051899 | |
| 0060081 | |
| 0007528 | |
| 0019226 | |
| 0006810 | |
| 0030666 | |
| 0016021 | |
| 0005886 | |
| 0005891 | |
| 0005262 | |
| 0005216 | |
| 0050877 | |
| 0042391 | |
| 0016020 | |
| 0005246 | |
| 0005509 |
| Rat chromosome position | 7q33-q34 |
|---|
| Swiss-Prot Accession | Q9Y698 |
|---|---|
| O88602 | |
| Q3ZB20 | |
| Q8C8F5 | |
| Q99PR9 | |
| Q71RJ2 | |
| Q2M1M1 | |
| Q5TGT3 | |
| Q9UGZ7 |
| Unigene ID | Hs.670146 |
|---|---|
| Mm.277338 | |
| Mm.400802 | |
| Rn.72939 |
| KEGG ID | hsa:10369 |
|---|---|
| mmu:12300 | |
| rno:84347 |
| Swiss-Prot ID | CCG2_HUMAN |
|---|---|
| CCG2_MOUSE | |
| Q3ZB20_MOUSE | |
| Q99PR9_RAT |
| Cell Localization | Membrane |
|---|---|
| Plasma membrane |
| IPI ID | IPI00001962 |
|---|---|
| IPI00132786 | |
| IPI00201313 | |
| IPI00474426 |
| Homologene ID | 4432 |
|---|
| RGD ID | 71095 |
|---|
| MGI ID | 1316660 |
|---|