| URN | urn:agi-llid:53373 |
|---|---|
| Connectivity | 19 |
| Name | Tpcn1 |
| Description | two pore segment channel 1 |
| Notes | Voltage-gated Ca(2+) and Na+ channels have 4 homologous domains, each containing 6 transmembrane segments, S1 to S6. TPCN1 is similar to these channels, but it has only 2 domains containing S1 to S6 (Ishibashi et al., 2000 [PubMed 10753632]).[supplied by OMIM] |
| Pathway | calcium transport pathway |
|---|---|
| calcium/calcium-mediated signaling pathway | |
| calcium-calcium-mediated signaling pathway | |
| calcium-calcium-mediated signaling pathway |
| GO Molecular Function | calcium ion binding |
|---|---|
| ion channel activity | |
| voltage-gated ion channel activity | |
| calcium channel activity |
| GO Cellular Component | membrane |
|---|---|
| integral to membrane |
| GO Biological Process | transmembrane transport |
|---|---|
| transport | |
| ion transport | |
| calcium ion transport |
| Ariadne Ontology | Other transport proteins |
|---|
| Group | Other transport proteins |
|---|---|
| transmembrane transport | |
| transport | |
| ion transport | |
| calcium ion transport | |
| calcium ion binding | |
| ion channel activity | |
| voltage-gated ion channel activity | |
| calcium channel activity | |
| membrane | |
| integral to membrane |
| MedScan ID | 53373 |
|---|
| Hugo ID | 18182 |
|---|
| Human chromosome position | 12q24.13 |
|---|
| LocusLink ID | 53373 |
|---|---|
| 252972 | |
| 246215 |
| Alias | TPC1 |
|---|---|
| FLJ20612 | |
| KIAA1169 | |
| two pore calcium channel protein 1 | |
| two-pore channel 1 | |
| two-pore segment channel 1 | |
| voltage-dependent calcium channel protein TPC1 | |
| mKIAA1169 | |
| 5730403B01Rik | |
| two pore channel 1 | |
| voltage-gated Ca channel | |
| 5730403B01 | |
| LOC246215 | |
| Tpcn1 | |
| two pore channel I | |
| two pore segment channel 1 | |
| two pore segment channel I | |
| voltage-gated Ca channels |
| Organism | Homo sapiens |
|---|---|
| Mus musculus | |
| Rattus norvegicus |
| OMIM ID | 609666 |
|---|
| Mouse chromosome position | 5 |
|---|
| GO ID | 0005262 |
|---|---|
| 0005244 | |
| 0006816 | |
| 0006811 | |
| 0055085 | |
| 0016021 | |
| 0016020 | |
| 0005216 | |
| 0006810 | |
| 0005509 |
| Rat chromosome position | 12q16 |
|---|
| Swiss-Prot Accession | Q9ULQ1 |
|---|---|
| Q9NWT7 | |
| Q9EQJ0 | |
| Q3UV38 | |
| Q9WTN5 | |
| A7E258 | |
| Q86XS9 | |
| Q8NC20 | |
| Q6P6R1 | |
| Q3V2Z6 | |
| Q6ZPW5 |
| PIR ID | JC7240 |
|---|
| Unigene ID | Hs.524763 |
|---|---|
| Mm.114054 | |
| Rn.24484 |
| KEGG ID | hsa:53373 |
|---|---|
| mmu:252972 | |
| rno:246215 |
| Swiss-Prot ID | TPC1_HUMAN |
|---|---|
| TPC1_RAT | |
| TPC1_MOUSE |
| Cell Localization | Membrane |
|---|---|
| Plasma membrane |
| IPI ID | IPI00385917 |
|---|---|
| IPI00795880 | |
| IPI00203176 | |
| IPI00111228 | |
| IPI00652986 | |
| IPI00164366 | |
| IPI00386050 | |
| IPI00798183 |
| Homologene ID | 9905 |
|---|
| RGD ID | 708494 |
|---|
| MGI ID | 2182472 |
|---|