| URN | urn:agi-llid:63900 |
|---|---|
| Connectivity | 57 |
| Name | Egln3 |
| Description | egl nine homolog 3 (C. elegans) |
| Notes | plays a role in regulation of cell proliferation [RGD] |
| Pathway | hypoxia inducible factor pathway |
|---|---|
| altered hypoxia inducible factor pathway |
| GO Molecular Function | oxidoreductase activity |
|---|---|
| L-ascorbic acid binding | |
| metal ion binding | |
| iron ion binding | |
| oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | |
| oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen |
| GO Cellular Component | cytoplasm |
|---|---|
| mitochondrion | |
| nucleus |
| GO Biological Process | regulation of cell proliferation |
|---|---|
| oxidation reduction | |
| apoptosis | |
| response to hypoxia |
| Group | regulation of cell proliferation |
|---|---|
| oxidation reduction | |
| apoptosis | |
| response to hypoxia | |
| oxidoreductase activity | |
| L-ascorbic acid binding | |
| metal ion binding | |
| iron ion binding | |
| oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | |
| oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen | |
| cytoplasm | |
| mitochondrion | |
| nucleus |
| MedScan ID | 63900 |
|---|
| Hugo ID | 14661 |
|---|
| Human chromosome position | 14q13.1 |
|---|
| LocusLink ID | 63900 |
|---|---|
| 112399 | |
| 112407 | |
| 54702 |
| Alias | PHD3 |
|---|---|
| HIFPH3 | |
| FLJ21620 | |
| MGC125998 | |
| MGC125999 | |
| egl nine homolog 3 | |
| HPH-1 | |
| HPH-3 | |
| HIF-PH3 | |
| HIF prolyl hydroxylase 3 | |
| HIF-prolyl hydroxylase 3 | |
| egl nine-like protein 3 isoform | |
| hypoxia-inducible factor prolyl hydroxylase 3 | |
| prolyl hydroxylase domain-containing protein 3 | |
| SM-20 | |
| AI505553 | |
| AI648162 | |
| 2610021G09Rik | |
| PHD-3 | |
| egl nine homolog 3, mitochondrial | |
| factor-responsive smooth muscle protein | |
| Sm20 | |
| 2610021G09 | |
| EGL nine (C.elegans) homolog 3 | |
| EGL nine (C.elegans) homolog III | |
| egl nine homolog 3 (C. elegans) | |
| EGL nine homolog III | |
| EGLN3 | |
| LOC360412 | |
| LOC497816 | |
| rat smooth muscle protein SM-20 |
| Organism | Homo sapiens |
|---|---|
| Mus musculus | |
| Rattus norvegicus |
| OMIM ID | 606426 |
|---|
| Mouse chromosome position | 12 |
|---|
| GO ID | 0031418 |
|---|---|
| 0005506 | |
| 0046872 | |
| 0016705 | |
| 0016702 | |
| 0006915 | |
| 0055114 | |
| 0042127 | |
| 0001666 | |
| 0005737 | |
| 0005634 | |
| 0016491 | |
| 0005739 |
| Rat chromosome position | 6q23 |
|---|
| Swiss-Prot Accession | Q9H6Z9 |
|---|---|
| Q3T1B0 | |
| Q91UZ4 | |
| Q62630 | |
| Q2TA79 | |
| Q3B8N4 | |
| Q6P1R2 | |
| Q3TCG8 | |
| Q8C8M6 | |
| Q8CCA8 | |
| Q8R5C7 |
| PIR ID | A53770 |
|---|
| Unigene ID | Hs.135507 |
|---|---|
| Mm.133037 | |
| Rn.10994 |
| KEGG ID | hsa:112399 |
|---|---|
| mmu:112407 | |
| rno:54702 |
| EC Number | 1.14.11.- |
|---|
| Swiss-Prot ID | EGLN3_RAT |
|---|---|
| EGLN3_HUMAN | |
| EGLN3_MOUSE |
| Cell Localization | Mitochondrion |
|---|---|
| Cytoplasm | |
| Nucleus |
| IPI ID | IPI00326540 |
|---|---|
| IPI00004971 | |
| IPI00126252 | |
| IPI00793033 |
| Homologene ID | 32531 |
|---|
| RGD ID | 71019 |
|---|
| MGI ID | 1932288 |
|---|