| URN | urn:agi-llid:7536 |
|---|---|
| Total Entities | 0 |
| Connectivity | 57 |
| Name | Sf1 |
| Description | splicing factor 1 |
| Notes | This gene encodes a nuclear pre-mRNA splicing factor. The encoded protein specifically recognizes the intron branch point sequence and is required for the early stages of spliceosome assembly. Alternate splicing results in multiple transcript variants. [provided by RefSeq, May 2010] |
| GO Molecular Function | transcription corepressor activity |
|---|---|
| nucleic acid binding | |
| RNA binding | |
| metal ion binding | |
| zinc ion binding |
| GO Cellular Component | spliceosomal complex |
|---|---|
| nucleolus | |
| ribosome | |
| cytoplasm | |
| nucleus |
| GO Biological Process | Leydig cell differentiation |
|---|---|
| male sex determination | |
| regulation of steroid biosynthetic process | |
| cell cycle process | |
| negative regulation of smooth muscle cell proliferation | |
| regulation of transcription, DNA-templated | |
| transcription, DNA-templated | |
| RNA splicing | |
| mRNA processing | |
| mRNA splicing, via spliceosome | |
| spliceosomal complex assembly | |
| mRNA 3'-splice site recognition |
| Pathway | spliceosomal pathway |
|---|---|
| spliceosome pathway |
| Group | mRNA processing |
|---|---|
| Leydig cell differentiation | |
| male sex determination | |
| regulation of steroid biosynthetic process | |
| cell cycle process | |
| negative regulation of smooth muscle cell proliferation | |
| regulation of transcription, DNA-templated | |
| transcription corepressor activity | |
| transcription, DNA-templated | |
| RNA splicing | |
| mRNA processing | |
| mRNA splicing, via spliceosome | |
| spliceosomal complex assembly | |
| mRNA 3'-splice site recognition | |
| nucleic acid binding | |
| RNA binding | |
| metal ion binding | |
| zinc ion binding | |
| spliceosomal complex | |
| nucleolus | |
| ribosome | |
| cytoplasm | |
| nucleus |
| LocusLink ID | 7536 |
|---|---|
| 22668 | |
| 117855 |
| Cell Localization | Nucleus |
|---|
| GO ID | 0003723 |
|---|---|
| 0003676 | |
| 0003714 | |
| 0008270 | |
| 0033327 | |
| 0022402 | |
| 0000389 | |
| 0000398 | |
| 0030238 | |
| 0050810 | |
| 0006355 | |
| 0000245 | |
| 0006351 | |
| 0005730 | |
| 0005634 | |
| 0005840 | |
| 0005681 | |
| 0046872 | |
| 0008380 | |
| 0006397 | |
| 0048662 | |
| 0005737 |
| Alias | BBP |
|---|---|
| MBBP | |
| ZFM1 | |
| ZNF162 | |
| D11S636 | |
| ZCCHC25 | |
| splicing factor 1 | |
| zinc finger protein 162 | |
| transcription factor ZFM1 | |
| zinc finger gene in MEN1 locus | |
| mammalian branch point-binding protein | |
| MZFM | |
| WBP4 | |
| CW17R | |
| Zfp162 | |
| BB094781 | |
| CW17 | |
| SF1/mBBP | |
| splicing factor I | |
| ZFM I | |
| OTTMUSP00000029805 | |
| OTTHUMP00000069749 | |
| 1K1G_A | |
| OTTHUMP00000069752 | |
| OTTMUSP00000020162 | |
| mBBP/SF1 | |
| OTTHUMP00000069750 | |
| OTTMUSP00000020160 |
| Mouse chromosome position | 19 |
|---|
| OMIM ID | 601516 |
|---|
| Rat chromosome position | 1q43 |
|---|
| Hugo ID | 12950 |
|---|
| Human chromosome position | 11q13 |
|---|
| Swiss-Prot Accession | Q15637 |
|---|---|
| Q3UI45 | |
| E9Q4Q2 | |
| Q3TZI3 | |
| Q64213 | |
| F1LSC3 | |
| I6L9G4 | |
| F1LM37 | |
| B7Z1Q1 | |
| C9JJE2 | |
| Q14818 | |
| Q14819 | |
| Q15913 | |
| Q8IY00 | |
| Q92744 | |
| Q92745 | |
| Q969H7 | |
| Q9BW01 | |
| Q9UEI0 |
| PIR ID | G02919 |
|---|
| Unigene ID | Hs.502829 |
|---|---|
| Mm.256422 | |
| Rn.1074 | |
| Rn.220071 |
| KEGG ID | hsa:7536 |
|---|---|
| mmu:22668 | |
| rno:117855 |
| Swiss-Prot ID | SF01_HUMAN |
|---|
| Ensembl ID | ENSG00000168066 |
|---|---|
| ENSP00000366604 | |
| ENST00000377387 | |
| ENSP00000366607 | |
| ENST00000377390 | |
| ENSP00000334414 | |
| ENST00000334944 | |
| ENSP00000366611 | |
| ENST00000377394 | |
| ENSP00000227503 | |
| ENST00000227503 | |
| ENSP00000413084 | |
| ENST00000422298 | |
| ENSMUSG00000024949 | |
| ENSMUSP00000121309 | |
| ENSMUST00000131252 | |
| ENSRNOG00000021085 | |
| ENSRNOP00000041676 | |
| ENSRNOT00000044866 |
| Homologene ID | 6461 |
|---|
| Organism | Homo sapiens |
|---|---|
| Mus musculus | |
| Rattus norvegicus |
| MGI ID | 1095403 |
|---|
| RGD ID | 620645 |
|---|
| MedScan ID | 7536 |
|---|