| URN | urn:agi-llid:10569 |
|---|---|
| Total Entities | 0 |
| Connectivity | 36 |
| Name | Slu7 |
| Description | SLU7 splicing factor homolog (S. cerevisiae) |
| Notes | Pre-mRNA splicing occurs in two sequential transesterification steps. The protein encoded by this gene is a splicing factor that has been found to be essential during the second catalytic step in the pre-mRNA splicing process. It associates with the spliceosome and contains a zinc knuckle motif that is found in other splicing factors and is involved in protein-nucleic acid and protein-protein interactions. [provided by RefSeq, Jul 2008] |
| GO Molecular Function | second spliceosomal transesterification activity |
|---|---|
| nucleic acid binding | |
| pre-mRNA 3'-splice site binding | |
| metal ion binding | |
| zinc ion binding |
| GO Cellular Component | spliceosomal complex |
|---|---|
| nucleolus | |
| small nuclear ribonucleoprotein complex | |
| nuclear speck | |
| catalytic step 2 spliceosome | |
| cytoplasm | |
| intracellular membrane-bounded organelle | |
| nucleus |
| GO Biological Process | cellular response to heat |
|---|---|
| RNA splicing | |
| mRNA processing | |
| RNA splicing, via transesterification reactions | |
| mRNA splicing, via spliceosome | |
| alternative mRNA splicing, via spliceosome | |
| mRNA 3'-splice site recognition | |
| intracellular protein transport |
| Pathway | spliceosomal pathway |
|---|---|
| spliceosome pathway |
| Group | mRNA processing |
|---|---|
| cellular response to heat | |
| second spliceosomal transesterification activity | |
| RNA splicing | |
| mRNA processing | |
| RNA splicing, via transesterification reactions | |
| mRNA splicing, via spliceosome | |
| alternative mRNA splicing, via spliceosome | |
| mRNA 3'-splice site recognition | |
| intracellular protein transport | |
| nucleic acid binding | |
| pre-mRNA 3'-splice site binding | |
| metal ion binding | |
| zinc ion binding | |
| spliceosomal complex | |
| nucleolus | |
| small nuclear ribonucleoprotein complex | |
| nuclear speck | |
| catalytic step 2 spliceosome | |
| cytoplasm | |
| intracellular membrane-bounded organelle | |
| nucleus |
| LocusLink ID | 10569 |
|---|---|
| 193116 | |
| 303057 |
| Cell Localization | Nucleus |
|---|---|
| Cytoplasm |
| GO ID | 0030628 |
|---|---|
| 0000386 | |
| 0008270 | |
| 0000375 | |
| 0000380 | |
| 0034605 | |
| 0006886 | |
| 0000389 | |
| 0000398 | |
| 0071013 | |
| 0005737 | |
| 0043231 | |
| 0016607 | |
| 0005730 | |
| 0005634 | |
| 0030532 | |
| 0005681 | |
| 0046872 | |
| 0003676 | |
| 0008380 | |
| 0006397 |
| Alias | 9G8 |
|---|---|
| hSlu7 | |
| pre-mRNA-splicing factor SLU7 | |
| splicing factor | |
| step II splicing factor SLU7 | |
| zinc knuckle motif containing | |
| AU018913 | |
| D3Bwg0878e | |
| D11Ertd730e | |
| RP23-26M1.8 | |
| OTTMUSP00000005614 | |
| SLU7 splicing factor homolog (S. cerevisiae) | |
| SLU7 splicing factor | |
| SLU7 | |
| MGC9280 | |
| MGC31026 | |
| LOC303057 | |
| LOC216689 | |
| DNA segment, Chr 3, Brigham & Women's Genetics 0878 expressed | |
| DNA segment, Chr 11, ERATO Doi 730, expressed | |
| OTTMUSP00000005613 |
| Mouse chromosome position | 11 |
|---|
| OMIM ID | 605974 |
|---|
| Rat chromosome position | 10q21 |
|---|
| Hugo ID | 16939 |
|---|
| Human chromosome position | 5q33.3 |
|---|
| Swiss-Prot Accession | O95391 |
|---|---|
| Q8BHJ9 | |
| B0BNL0 | |
| Q80ZG5 | |
| D3DQK2 | |
| Q3LUJ0 | |
| Q3LUJ1 | |
| Q6RXQ5 | |
| Q96FM9 | |
| Q3KQQ3 | |
| Q5SRU1 | |
| Q63ZX3 | |
| Q6P923 | |
| Q8BL59 | |
| Q8BXD5 | |
| Q8R5C1 | |
| Q91YV6 | |
| Q6P6G1 |
| Unigene ID | Hs.435342 |
|---|---|
| Mm.28200 | |
| Rn.137183 |
| KEGG ID | hsa:10569 |
|---|---|
| mmu:193116 | |
| rno:303057 |
| Swiss-Prot ID | SLU7_HUMAN |
|---|---|
| SLU7_MOUSE | |
| SLU7_RAT |
| Ensembl ID | ENSG00000164609 |
|---|---|
| ENSP00000297151 | |
| ENST00000297151 | |
| ENSMUSG00000020409 | |
| ENSMUSP00000020681 | |
| ENSMUST00000020681 | |
| ENSMUSP00000137281 | |
| ENSMUST00000178622 | |
| ENSRNOG00000003822 | |
| ENSRNOP00000005132 | |
| ENSRNOT00000005132 |
| Homologene ID | 4690 |
|---|
| Organism | Homo sapiens |
|---|---|
| Mus musculus | |
| Rattus norvegicus |
| MGI ID | 2385598 |
|---|
| RGD ID | 631432 |
|---|
| MedScan ID | 10569 |
|---|