| URN | urn:agi-llid:4927 |
|---|---|
| Total Entities | 0 |
| Connectivity | 78 |
| Name | Nup88 |
| Description | nucleoporin 88kDa |
| Notes | The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins, a family of 50 to 100 proteins, are the main components of the nuclear pore complex in eukaryotic cells. The protein encoded by this gene belongs to the nucleoporin family and is associated with the oncogenic nucleoporin CAN/Nup214 in a dynamic subcomplex. This protein is also overexpressed in a large number of malignant neoplasms and precancerous dysplasias. [provided by RefSeq, Jul 2008] |
| GO Molecular Function | porin activity |
|---|---|
| transporter activity |
| GO Cellular Component | integral component of membrane |
|---|---|
| pore complex | |
| nuclear pore | |
| nucleolus | |
| cytosol | |
| nucleus |
| GO Biological Process | small molecule metabolic process |
|---|---|
| transmembrane transport | |
| mitotic nuclear envelope disassembly | |
| mitotic cell cycle | |
| cytokine-mediated signaling pathway | |
| ion transport | |
| hexose transport | |
| glucose transport | |
| regulation of glucose transport | |
| carbohydrate metabolic process | |
| transport | |
| protein transport | |
| mRNA transport | |
| viral process |
| Pathway | ribosome biogenesis pathway |
|---|
| Group | Nuclear pore organization and biogenesis |
|---|---|
| Protein nucleus import | |
| Nuclear export | |
| small molecule metabolic process | |
| transmembrane transport | |
| mitotic nuclear envelope disassembly | |
| mitotic cell cycle | |
| cytokine-mediated signaling pathway | |
| porin activity | |
| ion transport | |
| hexose transport | |
| glucose transport | |
| regulation of glucose transport | |
| carbohydrate metabolic process | |
| transport | |
| transporter activity | |
| protein transport | |
| mRNA transport | |
| viral process | |
| integral component of membrane | |
| pore complex | |
| nuclear pore | |
| nucleolus | |
| cytosol | |
| nucleus | |
| Biofluids assayable substances |
| LocusLink ID | 4927 |
|---|---|
| 19069 | |
| 113929 |
| Cell Localization | Nucleus |
|---|---|
| Nuclear pore complex |
| GO ID | 0005215 |
|---|---|
| 0005975 | |
| 0019221 | |
| 0015758 | |
| 0008645 | |
| 0051028 | |
| 0000278 | |
| 0007077 | |
| 0015031 | |
| 0010827 | |
| 0044281 | |
| 0055085 | |
| 0016032 | |
| 0005829 | |
| 0005643 | |
| 0005730 | |
| 0005634 | |
| 0015288 | |
| 0006811 | |
| 0006810 | |
| 0016021 | |
| 0046930 |
| Alias | nuclear pore complex protein Nup88 |
|---|---|
| karyoporin | |
| nucleoporin Nup88 | |
| 88 kDa nucleoporin | |
| nuclear pore complex protein 88 | |
| Nup84 | |
| Prei2 | |
| DN-279H6.4 | |
| preimplantation protein 2 | |
| nucleoporin 88kDa | |
| nucleoporin Nup84 | |
| 88 kDa nuclear pore complex protein | |
| preimplantation protein II | |
| NUP88 | |
| MGC8530 | |
| OTTMUSP00000006372 | |
| OTTMUSP00000006373 | |
| OTTMUSP00000006374 | |
| 88kDa nuclear pore complex protein | |
| 88kDa nucleoporin | |
| LOC630141 | |
| nucleoporin 88 | |
| nucleoporin 88kD |
| Mouse chromosome position | 11 43.21 cM |
|---|
| OMIM ID | 602552 |
|---|
| Rat chromosome position | 10q24 |
|---|
| Hugo ID | 8067 |
|---|
| Human chromosome position | 17p13.2 |
|---|
| Swiss-Prot Accession | Q99567 |
|---|---|
| Q5QNU0 | |
| Q8BQF0 | |
| Q8CEC0 | |
| O08658 | |
| Q80Z13 | |
| Q8K090 | |
| D3DTM2 | |
| Q9BWE5 |
| Unigene ID | Hs.584784 |
|---|---|
| Mm.288962 | |
| Rn.11042 |
| KEGG ID | hsa:4927 |
|---|---|
| mmu:19069 | |
| rno:113929 |
| Swiss-Prot ID | NUP88_MOUSE |
|---|---|
| NUP88_RAT | |
| NUP88_HUMAN |
| Ensembl ID | ENSG00000108559 |
|---|---|
| ENSP00000458954 | |
| ENST00000573584 | |
| ENSMUSG00000040667 | |
| ENSMUSP00000048101 | |
| ENSMUST00000035283 | |
| ENSMUSP00000104171 | |
| ENSMUST00000108531 | |
| ENSMUSP00000104170 | |
| ENSMUST00000108530 | |
| ENSRNOG00000006126 | |
| ENSRNOP00000009015 | |
| ENSRNOT00000009015 |
| Homologene ID | 1901 |
|---|
| Organism | Homo sapiens |
|---|---|
| Mus musculus | |
| Rattus norvegicus |
| MGI ID | 104900 |
|---|
| RGD ID | 620182 |
|---|
| MedScan ID | 4927 |
|---|