| URN | urn:agi-llid:28987 |
|---|---|
| Total Entities | 0 |
| Connectivity | 14 |
| Name | Nob1 |
| Description | NIN1/RPN12 binding protein 1 homolog (S. cerevisiae) |
| Notes | In yeast, over 200 protein and RNA cofactors are required for ribosome assembly, and these are generally conserved in eukaryotes. These factors orchestrate modification and cleavage of the initial 35S precursor rRNA transcript into the mature 18S, 5.8S, and 25S rRNAs, folding of the rRNA, and binding of ribosomal proteins and 5S RNA. Nob1 is involved in pre-rRNA processing. In a late cytoplasmic processing step, Nob1 cleaves a 20S rRNA intermediate at cleavage site D to produce the mature 18S rRNA (Lamanna and Karbstein, 2009 [PubMed 19706509]).[supplied by OMIM, Nov 2010] |
| GO Molecular Function | metal ion binding |
|---|
| GO Cellular Component | nucleolus |
|---|---|
| cytoplasm | |
| nucleus |
| GO Biological Process | visual perception |
|---|---|
| maturation of SSU-rRNA | |
| ribosomal small subunit biogenesis |
| Pathway | ribosome biogenesis pathway |
|---|---|
| ribosome biogenesis pathway | |
| ribosome biogenesis pathway |
| Group | visual perception |
|---|---|
| maturation of SSU-rRNA | |
| ribosomal small subunit biogenesis | |
| metal ion binding | |
| nucleolus | |
| cytoplasm | |
| nucleus |
| LocusLink ID | 28987 |
|---|---|
| 67619 | |
| 291996 |
| Cell Localization | Nucleus |
|---|
| GO ID | 0046872 |
|---|---|
| 0005634 | |
| 0030490 | |
| 0042274 | |
| 0007601 | |
| 0005737 | |
| 0005730 |
| Alias | ART-4 |
|---|---|
| NOB1P | |
| MST158 | |
| MSTP158 | |
| PSMD8BP1 | |
| RNA-binding protein NOB1 | |
| protein ART-4 | |
| PSMD8 binding protein 1 | |
| nin one binding protein | |
| phosphorylation regulatory protein HP-10 | |
| adenocarcinoma antigen recognized by T lymphocytes 4 | |
| 1700021I09Rik | |
| 1700021I09 | |
| NIN1/RPN12 binding protein 1 homolog | |
| NIN1/RPN12 binding protein 1 homolog (S. cerevisiae) | |
| nin one-binding protein | |
| MGC156557 | |
| adenocarcinoma antigen recognized by T lymphocytes IV | |
| likely ortholog of mouse nin one binding protein | |
| LOC291996 | |
| MGC118441 | |
| MGC144649 | |
| MGC144650 | |
| LOC90015 |
| Mouse chromosome position | 8 |
|---|
| OMIM ID | 613586 |
|---|
| Rat chromosome position | 19q12 |
|---|
| Hugo ID | 29540 |
|---|
| Human chromosome position | 16q22.3 |
|---|
| Swiss-Prot Accession | Q9ULX3 |
|---|---|
| Q148S3 | |
| Q8BW10 | |
| Q6VEU1 | |
| A0JN09 | |
| Q7L6B7 | |
| Q7M4M4 | |
| Q7Z4B5 | |
| Q9NWB0 | |
| Q7TPR3 | |
| Q9CRD7 |
| PIR ID | A61382 |
|---|
| Unigene ID | Hs.271695 |
|---|---|
| Mm.334793 | |
| Rn.102586 |
| KEGG ID | hsa:28987 |
|---|---|
| mmu:67619 | |
| rno:291996 |
| Swiss-Prot ID | NOB1_RAT |
|---|---|
| NOB1_HUMAN | |
| NOB1_MOUSE |
| Ensembl ID | ENSG00000141101 |
|---|---|
| ENSP00000268802 | |
| ENST00000268802 | |
| ENSMUSG00000003848 | |
| ENSMUSP00000003946 | |
| ENSMUST00000003946 | |
| ENSRNOG00000021890 | |
| ENSRNOP00000031905 | |
| ENSRNOT00000034386 |
| Homologene ID | 31924 |
|---|
| Organism | Homo sapiens |
|---|---|
| Mus musculus | |
| Rattus norvegicus |
| MGI ID | 1914869 |
|---|
| RGD ID | 735222 |
|---|
| MedScan ID | 28987 |
|---|