| URN | urn:agi-llid:10399 |
|---|---|
| Total Entities | 0 |
| Connectivity | 775 |
| Name | Gnb2l1 |
| Description | guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1 |
| Notes | may act as a receptor for activated protein kinase C [RGD, Feb 2006] |
| GO Molecular Function | ion channel inhibitor activity |
|---|---|
| cysteine-type endopeptidase activator activity involved in apoptotic process | |
| protein tyrosine kinase inhibitor activity | |
| receptor activity | |
| protein complex scaffold | |
| enzyme binding | |
| receptor binding | |
| receptor tyrosine kinase binding | |
| protein kinase C binding | |
| protein phosphatase binding | |
| SH2 domain binding |
| GO Cellular Component | membrane |
|---|---|
| phagocytic cup | |
| small ribosomal subunit | |
| midbody | |
| intracellular | |
| plasma membrane | |
| cell projection | |
| cytoplasm | |
| cytosol | |
| perinuclear region of cytoplasm | |
| mitochondrion | |
| cytoskeleton | |
| nucleus | |
| dendrite | |
| perikaryon | |
| neuronal cell body |
| GO Biological Process | rhythmic process |
|---|---|
| positive regulation of GTPase activity | |
| positive regulation of cAMP catabolic process | |
| multicellular organismal development | |
| positive regulation of gastrulation | |
| gastrulation | |
| cell cycle | |
| regulation of cell cycle | |
| regulation of cell division | |
| intracellular signal transduction | |
| positive regulation of intrinsic apoptotic signaling pathway | |
| negative regulation of protein kinase B signaling | |
| negative regulation of Wnt signaling pathway | |
| protein kinase C-activating G-protein coupled receptor signaling pathway | |
| negative regulation of cell growth | |
| positive regulation of cell migration | |
| regulation of establishment of cell polarity | |
| apoptotic process | |
| positive regulation of apoptotic process | |
| activation of cysteine-type endopeptidase activity involved in apoptotic process | |
| regulation of establishment of protein localization to plasma membrane | |
| negative regulation of phagocytosis | |
| positive regulation of mitochondrial depolarization | |
| positive regulation of proteasomal ubiquitin-dependent protein catabolic process | |
| positive regulation of protein phosphorylation | |
| positive regulation of protein homooligomerization | |
| regulation of growth | |
| negative regulation of translation | |
| negative regulation of protein tyrosine kinase activity | |
| regulation of translation | |
| positive regulation of cyclic-nucleotide phosphodiesterase activity | |
| regulation of protein localization | |
| modulation by virus of host morphology or physiology | |
| protein localization |
| Pathway | CFTR-Related Ion-Channel Dysfunction in Cystic Fibrosis Airway Epithelium (Class III Mutations) |
|---|---|
| NGF/AP-1/TP53/MYC Expression Targets | |
| NGF/SMAD3/NF-kB Expression Targets | |
| ribosome biogenesis pathway |
| Group | Oncogenes |
|---|---|
| rhythmic process | |
| positive regulation of GTPase activity | |
| positive regulation of cAMP catabolic process | |
| multicellular organismal development | |
| positive regulation of gastrulation | |
| gastrulation | |
| cell cycle | |
| regulation of cell cycle | |
| regulation of cell division | |
| intracellular signal transduction | |
| positive regulation of intrinsic apoptotic signaling pathway | |
| negative regulation of protein kinase B signaling | |
| negative regulation of Wnt signaling pathway | |
| protein kinase C-activating G-protein coupled receptor signaling pathway | |
| negative regulation of cell growth | |
| ion channel inhibitor activity | |
| positive regulation of cell migration | |
| regulation of establishment of cell polarity | |
| apoptotic process | |
| positive regulation of apoptotic process | |
| activation of cysteine-type endopeptidase activity involved in apoptotic process | |
| cysteine-type endopeptidase activator activity involved in apoptotic process | |
| regulation of establishment of protein localization to plasma membrane | |
| negative regulation of phagocytosis | |
| positive regulation of mitochondrial depolarization | |
| positive regulation of proteasomal ubiquitin-dependent protein catabolic process | |
| positive regulation of protein phosphorylation | |
| positive regulation of protein homooligomerization | |
| regulation of growth | |
| negative regulation of translation | |
| negative regulation of protein tyrosine kinase activity | |
| protein tyrosine kinase inhibitor activity | |
| regulation of translation | |
| positive regulation of cyclic-nucleotide phosphodiesterase activity | |
| regulation of protein localization | |
| modulation by virus of host morphology or physiology | |
| protein localization | |
| receptor activity | |
| protein complex scaffold | |
| enzyme binding | |
| receptor binding | |
| receptor tyrosine kinase binding | |
| protein kinase C binding | |
| protein phosphatase binding | |
| SH2 domain binding | |
| membrane | |
| phagocytic cup | |
| small ribosomal subunit | |
| midbody | |
| intracellular | |
| plasma membrane | |
| cell projection | |
| cytoplasm | |
| cytosol | |
| perinuclear region of cytoplasm | |
| mitochondrion | |
| cytoskeleton | |
| nucleus | |
| dendrite | |
| perikaryon | |
| neuronal cell body |
| LocusLink ID | 10399 |
|---|---|
| 14694 | |
| 83427 |
| Cell Localization | Cell membrane |
|---|---|
| Cytoplasm | |
| Perinuclear region | |
| Cytoskeleton | |
| Nucleus | |
| Perikaryon | |
| Cell projection | |
| Dendrite | |
| Phagocytic cup |
| GO ID | 0042169 |
|---|---|
| 0008656 | |
| 0019899 | |
| 0008200 | |
| 0032947 | |
| 0005080 | |
| 0019903 | |
| 0030292 | |
| 0005102 | |
| 0030971 | |
| 0006919 | |
| 0007049 | |
| 0007369 | |
| 0019048 | |
| 0030178 | |
| 0030308 | |
| 0050765 | |
| 0051898 | |
| 0061099 | |
| 0017148 | |
| 0043547 | |
| 0043065 | |
| 0030822 | |
| 0030335 | |
| 0051343 | |
| 2000543 | |
| 2001244 | |
| 0051901 | |
| 0032436 | |
| 0032464 | |
| 0001934 | |
| 0051726 | |
| 0051302 | |
| 2000114 | |
| 0090003 | |
| 0032880 | |
| 0048511 | |
| 0005737 | |
| 0005856 | |
| 0005829 | |
| 0030425 | |
| 0030496 | |
| 0005739 | |
| 0043025 | |
| 0005634 | |
| 0043204 | |
| 0048471 | |
| 0001891 | |
| 0015935 | |
| 0004872 | |
| 0006915 | |
| 0035556 | |
| 0007275 | |
| 0008104 | |
| 0040008 | |
| 0006417 | |
| 0042995 | |
| 0005622 | |
| 0016020 | |
| 0005886 | |
| 0007205 |
| Alias | H12.3 |
|---|---|
| HLC-7 | |
| PIG21 | |
| RACK1 | |
| Gnb2-rs1 | |
| HLC7 | |
| guanine nucleotide-binding protein subunit beta-2-like 1 | |
| lung cancer oncogene 7 | |
| proliferation-inducing gene 21 | |
| receptor for activated C kinase 1 | |
| human lung cancer oncogene 7 protein | |
| receptor of activated protein kinase C 1 | |
| cell proliferation-inducing gene 21 protein | |
| guanine nucleotide binding protein beta polypeptide 2-like 1 | |
| guanine nucleotide-binding protein subunit beta-like protein 12.3 | |
| protein homologous to chicken B complex protein, guanine nucleotide binding | |
| p205 | |
| GB-like | |
| AL033335 | |
| RP23-14F5.6 | |
| 12-3 | |
| receptor for activated C kinase | |
| activated protein kinase C receptor | |
| guanine nucleotide binding protein related | |
| guanine nucleotide binding protein, beta 2, related sequence 1 | |
| guanine nucleotide binding protein, beta-2, related sequence 1 | |
| guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1 | |
| guanine nucleotide binding protein (G protein), beta polypeptide 2 like 1 sequence 1 | |
| rCG_34190 | |
| protein kinase C receptor | |
| receptor for activated protein kinase C | |
| guanine nucleotide binding protein, beta polypeptide 2-like 1 | |
| guanine nucleotide binding protein (G protein) beta polypeptide 2-like 1 | |
| RACK I | |
| protein kinase C receptors | |
| lung cancer oncogene VII | |
| LOC309294 | |
| receptor of activated C kinase 1 | |
| LOC90938 | |
| OTTMUSP00000005677 | |
| Receptor of activated protein kinase C I | |
| RACK1 scaffold protein | |
| RACK1 scaffolding protein | |
| receptor for activated C kinase RACK1 | |
| receptor for activated protein kinase C RACK1 | |
| LOC153763 | |
| OTTHUMP00000223930 | |
| receptor for activated protein kinase C 1 | |
| Gnb2l1 | |
| D4Mgi39 | |
| DNA Segment, Chr 4, Mouse Genome Informatics 39 | |
| LOC134379 | |
| Gnb2l I | |
| Gnb2-rs I | |
| guanine nucleotide binding (G), beta polypeptide 2-like | |
| Guanine nucleotide-binding protein beta subunit-like protein 12.3 | |
| GB-likes | |
| guanine nucleotide binding protein (G protein), beta polypeptide 2-like I | |
| guanine nucleotide binding, beta polypeptide 2-like | |
| guanine nucleotide binding, beta 2, related sequence | |
| guanine nucleotide binding protein, beta polypeptide 2-like I | |
| guanine nucleotide binding protein, beta 2, related sequence I |
| Mouse chromosome position | 11 |
|---|
| OMIM ID | 176981 |
|---|
| Rat chromosome position | 10q21 |
|---|
| Hugo ID | 4399 |
|---|
| Human chromosome position | 5q35.3 |
|---|
| Swiss-Prot Accession | E9KL35 |
|---|---|
| P63244 | |
| P68040 | |
| P63245 | |
| P25388 | |
| P99049 | |
| Q3THP0 | |
| Q3THY7 | |
| Q3TKQ0 | |
| Q3TW88 | |
| Q5NCC5 | |
| Q5NCC6 | |
| Q9CSQ0 | |
| Q9ERM6 | |
| B3KTJ0 | |
| D3DWS0 | |
| Q53HU2 | |
| Q5J8M6 | |
| Q5VLR4 | |
| Q6FH47 |
| PIR ID | S38398 |
|---|---|
| A36986 | |
| B33928 |
| Unigene ID | Hs.5662 |
|---|---|
| Mm.5305 | |
| Rn.55487 |
| KEGG ID | hsa:10399 |
|---|---|
| mmu:14694 | |
| rno:83427 | |
| rno:100911540 |
| Swiss-Prot ID | GBLP_MOUSE |
|---|---|
| GBLP_RAT | |
| GBLP_HUMAN |
| Ensembl ID | ENSG00000204628 |
|---|---|
| ENSP00000366013 | |
| ENST00000376817 | |
| ENSP00000426909 | |
| ENST00000512805 | |
| ENSMUSG00000020372 | |
| ENSMUSP00000020640 | |
| ENSMUST00000020640 | |
| ENSRNOG00000002390 | |
| ENSRNOP00000003334 | |
| ENSRNOT00000003334 |
| Homologene ID | 4446 |
|---|
| Organism | Homo sapiens |
|---|---|
| Mus musculus | |
| Rattus norvegicus |
| MGI ID | 101849 |
|---|
| RGD ID | 69229 |
|---|
| MedScan ID | 10399 |
|---|