Protein Rlbp1

URN urn:agi-llid:6017
Connectivity 17
Name Rlbp1
Description retinaldehyde binding protein 1
Notes The protein encoded by this gene is a 36-kD water-soluble protein which carries 11-cis-retinaldehyde or 11-cis-retinal as physiologic ligands. It may be a functional component of the visual cycle. Mutations of this gene have been associated with severe rod-cone dystrophy, Bothnia dystrophy (nonsyndromic autosomal recessive retinitis pigmentosa) and retinitis punctata albescens. [provided by RefSeq]

Pathway retinoid cycle metabolic pathway

GO Molecular Function transporter activity
retinol binding
11-cis retinal binding

GO Cellular Component intracellular
soluble fraction
cytoplasm

GO Biological Process response to stimulus
transport
visual perception
vitamin A metabolic process

Group transporter activity
response to stimulus
transport
visual perception
vitamin A metabolic process
retinol binding
11-cis retinal binding
intracellular
soluble fraction
cytoplasm

MedScan ID 6017

Hugo ID 10024

Human chromosome position 15q26

LocusLink ID 6017
19771
293049

Alias CRALBP
MGC3663
retinaldehyde-binding protein 1
cellular retinaldehyde-binding protein
cellular retinaldehyde-binding protein-1
3110056M11Rik
3110056M11
3110056M11Rik(2)
Newfoundland rod-cone dystrophy, included
retinaldehyde binding protein 1
retinaldehyde binding protein I
Retinaldehyde-binding protein-1 (cellular)
RLBP I
RLBP1

Organism Homo sapiens
Mus musculus
Rattus norvegicus

GenBank ID NC_000015
NM_000326
NP_000317
NT_010274
NW_925940
NW_001838222
NG_008116
AC_000058
AC_000147
AC124068
CH471101
EAX02038
L34219
AAA65123
AK312457
BAG35364
BC004199
AAH04199
BF940774
BG205561
BM704704
BM921294
BX490622
DQ980611
J04213
AAA60251
P12271
NC_000073
NM_020599
NP_065624
NT_039428
NW_001030863
AC_000029
NM_001173483
AC160464
AF084638
AAC99427
AF084639
AF084640
AF084641
AF084642
CH466543
EDL07072
EDL07073
AK014227
BAB29216
AK140622
BAE24430
BC016268
AAH16268
CO040983
Q544Y3
Q9Z275
NC_005100
NM_001106274
NW_047560
NW_001084766
AC_000069
CH473980
EDM08575
EDM08576

OMIM ID 180090
607475
136880
607476
268000

Mouse chromosome position 7 39.0 cM

GO ID 0005502
0019841
0005215
0050896
0007601
0006776
0005737
0005622
0005625
0006810

Rat chromosome position 1q31

Swiss-Prot Accession P12271
Q544Y3
Q9Z275
B2R667

PIR ID B31955

Unigene ID Hs.1933
Mm.41653
Rn.41007

KEGG ID hsa:6017
mmu:19771
rno:293049

Swiss-Prot ID RLBP1_MOUSE
RLBP1_HUMAN
Q544Y3_MOUSE
B2R667_HUMAN

Cell Localization Cytoplasm

IPI ID IPI00226080
IPI00218633
IPI00874161
IPI00798306
IPI00364357

Homologene ID 68046

RGD ID 1309649

MGI ID 97930