| URN | urn:agi-llid:1382 |
|---|---|
| Connectivity | 63 |
| Name | Crabp2 |
| Description | cellular retinoic acid binding protein 2 |
| Notes | A number of specific carrier proteins for members of the vitamin A family have been discovered. Cellular retinoic acid binding proteins (CRABP) are low molecular weight proteins whose precise function remains unknown. The inducibility of the CRABP2 gene suggests that this isoform is important in retinoic acid-mediated regulation of human skin growth and differentiation. It has been postulated that the CRABP2 gene is transcriptionally regulated by a newly synthesized regulatory protein. [provided by RefSeq] |
| Pathway | retinoic acid metabolic pathway |
|---|
| GO Molecular Function | transporter activity |
|---|---|
| lipid binding | |
| cyclin binding | |
| retinal binding | |
| retinol binding | |
| retinoid binding | |
| retinoic acid binding |
| GO Cellular Component | cytoplasm |
|---|---|
| nucleus |
| GO Biological Process | transport |
|---|---|
| epidermis development | |
| embryonic forelimb morphogenesis | |
| signal transduction | |
| regulation of transcription, DNA-dependent | |
| retinoic acid metabolic process | |
| lipid transport |
| Group | transporter activity |
|---|---|
| transport | |
| epidermis development | |
| embryonic forelimb morphogenesis | |
| signal transduction | |
| regulation of transcription, DNA-dependent | |
| retinoic acid metabolic process | |
| lipid transport | |
| lipid binding | |
| cyclin binding | |
| retinal binding | |
| retinol binding | |
| retinoid binding | |
| retinoic acid binding | |
| cytoplasm | |
| nucleus |
| MedScan ID | 1382 |
|---|
| Hugo ID | 2339 |
|---|
| Human chromosome position | 1q21.3 |
|---|
| LocusLink ID | 1382 |
|---|---|
| 12904 | |
| 29563 |
| Alias | RBP6 |
|---|---|
| CRABP-II | |
| RP11-66D17.4 | |
| cellular retinoic acid-binding protein 2 | |
| OTTHUMP00000038732 | |
| cellular retinoic acid-binding protein II | |
| Crabp-2 | |
| CrabpII | |
| AI893628 | |
| cellular lipid-binding protein | |
| cellular retinoic acid binding protein II | |
| cellular retinoic acid binding protein 2 | |
| Crabp2 | |
| LOC229505 | |
| OTTHUMP00000038730 | |
| Retinoic acid-binding protein II, cellular | |
| RETINOIC ACID-BINDING PROTEIN II, CELLULAR (CRABP-II) |
| Organism | Homo sapiens |
|---|---|
| Mus musculus | |
| Rattus norvegicus |
| OMIM ID | 180231 |
|---|
| Mouse chromosome position | 3 |
|---|
| GO ID | 0008289 |
|---|---|
| 0016918 | |
| 0001972 | |
| 0005501 | |
| 0019841 | |
| 0005215 | |
| 0035115 | |
| 0008544 | |
| 0006355 | |
| 0042573 | |
| 0007165 | |
| 0005737 | |
| 0005634 | |
| 0030332 | |
| 0006810 | |
| 0006869 |
| Rat chromosome position | 2q34 |
|---|
| Swiss-Prot Accession | P29373 |
|---|---|
| Q5SYZ4 | |
| P22935 | |
| P51673 | |
| Q6XL81 | |
| B2R4Z8 | |
| Q6ICN6 | |
| D3DVC5 |
| PIR ID | A45057 |
|---|---|
| I53298 | |
| A42495 |
| Unigene ID | Hs.405662 |
|---|---|
| Mm.4757 | |
| Rn.11333 |
| KEGG ID | hsa:1382 |
|---|---|
| mmu:12904 | |
| rno:29563 |
| Swiss-Prot ID | RABP2_HUMAN |
|---|---|
| RABP2_RAT | |
| RABP2_MOUSE | |
| D3DVC5_HUMAN | |
| B2R4Z8_HUMAN |
| Cell Localization | Cytoplasm |
|---|---|
| Nucleus |
| IPI ID | IPI00216088 |
|---|---|
| IPI00231750 | |
| IPI00133687 | |
| IPI00643056 |
| Homologene ID | 1415 |
|---|
| RGD ID | 62070 |
|---|
| MGI ID | 88491 |
|---|