| URN | urn:agi-llid:2979 |
|---|---|
| Connectivity | 21 |
| Name | Guca1b |
| Description | guanylate cyclase activator 1B (retina) |
| Notes | The protein encoded by this gene is a calcium-binding protein that activates photoreceptor guanylate cyclases. This gene may have arisen due to a gene duplication event since there is a highly similar gene clustered with it on chromosome 6. Mutations in this gene can cause a form of retinitis pigmentosa. [provided by RefSeq] |
| Pathway | visual phototransduction pathway |
|---|
| GO Molecular Function | calcium ion binding |
|---|---|
| guanylate cyclase regulator activity | |
| calcium sensitive guanylate cyclase activator activity |
| GO Cellular Component | membrane |
|---|---|
| plasma membrane |
| GO Biological Process | response to stimulus |
|---|---|
| cell-cell signaling | |
| body fluid secretion | |
| visual perception | |
| phototransduction | |
| regulation of guanylate cyclase activity | |
| receptor guanylyl cyclase signaling pathway |
| Group | response to stimulus |
|---|---|
| cell-cell signaling | |
| body fluid secretion | |
| visual perception | |
| phototransduction | |
| regulation of guanylate cyclase activity | |
| receptor guanylyl cyclase signaling pathway | |
| calcium ion binding | |
| guanylate cyclase regulator activity | |
| calcium sensitive guanylate cyclase activator activity | |
| membrane | |
| plasma membrane |
| MedScan ID | 2979 |
|---|
| Hugo ID | 4679 |
|---|
| Human chromosome position | 6p21.1 |
|---|
| LocusLink ID | 2979 |
|---|---|
| 107477 | |
| 316218 |
| Alias | RP48 |
|---|---|
| GCAP2 | |
| GUCA2 | |
| DKFZp686E1183 | |
| RP1-139D8.1 | |
| guanylyl cyclase-activating protein 2 | |
| GCAP 2 | |
| guanylate cyclase-activating protein, photoreceptor 2 | |
| BC018258 | |
| MGC36472 | |
| GCAP2 (retina) | |
| guanylate cyclase activator 1B | |
| guanylate cyclase activator 1B (retina) | |
| guanylate cyclase-activating protein 2 | |
| Guanylyl cyclase activating protein 2 | |
| Guanylyl cyclase activating protein II | |
| Guca1b | |
| OTTHUMP00000016398 | |
| OTTHUMP00000039781 |
| Organism | Homo sapiens |
|---|---|
| Mus musculus | |
| Rattus norvegicus |
| OMIM ID | 602275 |
|---|
| Mouse chromosome position | 17 |
|---|
| GO ID | 0005509 |
|---|---|
| 0008048 | |
| 0030249 | |
| 0007589 | |
| 0007267 | |
| 0007602 | |
| 0007168 | |
| 0031282 | |
| 0050896 | |
| 0007601 | |
| 0005886 | |
| 0016020 |
| Rat chromosome position | 9q12 |
|---|
| Swiss-Prot Accession | Q9UMX6 |
|---|---|
| Q7Z3V9 | |
| Q8VBV8 | |
| Q9NU15 |
| Unigene ID | Hs.446529 |
|---|---|
| Mm.59151 | |
| Rn.38113 |
| KEGG ID | hsa:2979 |
|---|---|
| mmu:107477 | |
| rno:316218 |
| Swiss-Prot ID | GUC1B_MOUSE |
|---|---|
| GUC1B_HUMAN | |
| Q7Z3V9_HUMAN |
| Cell Localization | Cell membrane |
|---|
| IPI ID | IPI00121448 |
|---|---|
| IPI00219035 | |
| IPI00743844 | |
| IPI00874622 | |
| IPI00371758 |
| Homologene ID | 1586 |
|---|
| RGD ID | 1308191 |
|---|
| MGI ID | 1194489 |
|---|