| URN | urn:agi-llid:2780 |
|---|---|
| Connectivity | 4 |
| Name | Gnat2 |
| Description | guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 |
| Notes | Transducin is a 3-subunit guanine nucleotide-binding protein (G protein) which stimulates the coupling of rhodopsin and cGMP-phoshodiesterase during visual impulses. The transducin alpha subunits in rods and cones are encoded by separate genes. This gene encodes the alpha subunit in cones. [provided by RefSeq] |
| Pathway | visual phototransduction pathway |
|---|
| GO Molecular Function | signal transducer activity |
|---|---|
| nucleotide binding | |
| guanyl nucleotide binding | |
| GTP binding | |
| GTPase activity | |
| G-protein coupled photoreceptor activity |
| GO Cellular Component | photoreceptor inner segment |
|---|---|
| photoreceptor outer segment membrane | |
| plasma membrane | |
| membrane fraction | |
| heterotrimeric G-protein complex | |
| photoreceptor outer segment |
| GO Biological Process | response to stimulus |
|---|---|
| retinal cone cell development | |
| visual perception | |
| phototransduction | |
| signal transduction | |
| G-protein signaling, coupled to cGMP nucleotide second messenger | |
| elevation of cytosolic calcium ion concentration | |
| detection of chemical stimulus involved in sensory perception of bitter taste | |
| detection of light stimulus involved in visual perception | |
| response to light intensity | |
| G-protein coupled receptor protein signaling pathway |
| Ariadne Ontology | Gt |
|---|
| Group | Gt |
|---|---|
| response to stimulus | |
| retinal cone cell development | |
| visual perception | |
| phototransduction | |
| signal transduction | |
| G-protein signaling, coupled to cGMP nucleotide second messenger | |
| elevation of cytosolic calcium ion concentration | |
| detection of chemical stimulus involved in sensory perception of bitter taste | |
| detection of light stimulus involved in visual perception | |
| response to light intensity | |
| G-protein coupled receptor protein signaling pathway | |
| signal transducer activity | |
| nucleotide binding | |
| guanyl nucleotide binding | |
| GTP binding | |
| GTPase activity | |
| G-protein coupled photoreceptor activity | |
| photoreceptor inner segment | |
| photoreceptor outer segment membrane | |
| plasma membrane | |
| membrane fraction | |
| heterotrimeric G-protein complex | |
| photoreceptor outer segment |
| MedScan ID | 2780 |
|---|
| Hugo ID | 4394 |
|---|
| Human chromosome position | 1p13.1 |
|---|
| LocusLink ID | 2780 |
|---|---|
| 14686 | |
| 365901 |
| Alias | ACHM4 |
|---|---|
| GNATC | |
| RP5-1160K1.4 | |
| guanine nucleotide-binding protein G(t) subunit alpha-2 | |
| transducin alpha-2 chain | |
| cone-type transducin alpha subunit | |
| transducin, cone-specific, alpha polypeptide | |
| guanine nucleotide-binding protein G(t), alpha-2 subunit | |
| Gt-2 | |
| Gnat-2 | |
| Tcalpha | |
| AW490837 | |
| RP23-89M15.3 | |
| OTTMUSP00000007612 | |
| OTTMUSP00000007617 | |
| G protein, alpha transducing activity polypeptide 2 | |
| G protein, alpha transducing activity polypeptide II | |
| G(T), alpha II | |
| G(T), alpha-2 | |
| G(T), alpha-2 subunit | |
| Gnat2 | |
| guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 | |
| guanine nucleotide binding protein, alpha transducing 2 | |
| guanine nucleotide binding protein, alpha transducing activity polypeptide 2 | |
| guanine nucleotide binding protein, alpha transducing II | |
| LOC92084 | |
| OTTHUMP00000013354 |
| Organism | Homo sapiens |
|---|---|
| Mus musculus | |
| Rattus norvegicus |
| OMIM ID | 139340 |
|---|
| Mouse chromosome position | 3 49.0 cM |
|---|
| GO ID | 0008020 |
|---|---|
| 0005525 | |
| 0019001 | |
| 0000166 | |
| 0004871 | |
| 0007186 | |
| 0050908 | |
| 0007602 | |
| 0050896 | |
| 0046549 | |
| 0007601 | |
| 0005834 | |
| 0001917 | |
| 0001750 | |
| 0042622 | |
| 0005886 | |
| 0003924 | |
| 0007199 | |
| 0001580 | |
| 0007204 | |
| 0009642 | |
| 0007165 | |
| 0005624 |
| Rat chromosome position | 2q34 |
|---|
| Swiss-Prot Accession | P19087 |
|---|---|
| Q5T697 | |
| Q16162 | |
| A2AE33 | |
| P50149 | |
| Q8BSY7 | |
| Q9D7B3 |
| PIR ID | A47219 |
|---|
| Unigene ID | Hs.36973 |
|---|---|
| Mm.439652 | |
| Rn.219804 |
| KEGG ID | hsa:2780 |
|---|---|
| mmu:14686 | |
| rno:365901 |
| Swiss-Prot ID | GNAT2_MOUSE |
|---|---|
| GNAT2_HUMAN | |
| Q5T697_HUMAN | |
| A2AE33_MOUSE |
| Cell Localization | Cytoplasm |
|---|
| IPI ID | IPI00228620 |
|---|---|
| IPI00217269 | |
| IPI00648939 | |
| IPI00648622 | |
| IPI00649933 | |
| IPI00368308 |
| Homologene ID | 21092 |
|---|
| RGD ID | 1309514 |
|---|
| MGI ID | 95779 |
|---|