Protein Rcvrn

URN urn:agi-llid:5957
Connectivity 55
Name Rcvrn
Description recoverin
Notes This gene encodes a member of the recoverin family of neuronal calcium sensors. The encoded protein contains three calcium-binding EF-hand domains and may prolong the termination of the phototransduction cascade in the retina by blocking the phosphorylation of photo-activated rhodopsin. Recoverin may be the antigen responsible for cancer-associated retinopathy. [provided by RefSeq]

Pathway visual phototransduction pathway

GO Molecular Function calcium ion binding
calcium sensitive guanylate cyclase activator activity

GO Biological Process response to stimulus
visual perception
phototransduction
signal transduction
regulation of calcium ion transport

Group response to stimulus
visual perception
phototransduction
signal transduction
regulation of calcium ion transport
calcium ion binding
calcium sensitive guanylate cyclase activator activity

MedScan ID 5957

Hugo ID 9937

Human chromosome position 17p13.1

LocusLink ID 5957
19674
140936

Alias RCV1
recoverin
cancer associated retinopathy antigen
cancer-associated retinopathy protein
CAR
MGC129468
S-modulin
RP23-338M9.3
OTTMUSP00000006130
guanylate cyclase activator
cancer associated retinopathy protein
23 kDa photoreceptor cell-specific protein
RCV I
Rcvrn

Organism Homo sapiens
Mus musculus
Rattus norvegicus

GenBank ID NC_000017
NM_002903
NP_002894
NT_010718
NW_001838403
NW_926584
AC_000060
AC_000149
AC026591
CH471108
EAW90014
AB001838
BAA19460
AK314129
BAG36819
BC001720
AAH01720
BT009838
AAP88840
S43855
AAB23163
S45545
AAB23392
S62028
AAB26894
P35243
Q53XL0
DQ892822
ABM83748
DQ896068
ABM87067
NC_000077
NM_009038
NP_033064
NT_096135
NW_001030477
AC_000033
AL646097
CH466601
EDL10434
BC110564
AAI10565
CK617354
CK617615
CK627353
X66196
CAA46958
P34057
NC_005109
NM_080901
NP_543177
NW_001084656
NW_047334
AC_000078
CH473948
EDM04794
AY063482
AAL38975
Q8VH47

OMIM ID 179618

Mouse chromosome position 11 35.0 cM

GO ID 0005509
0008048
0007602
0051924
0050896
0007165
0007601

Rat chromosome position 10q24

Swiss-Prot Accession P35243
Q53XL0
P34057
Q2TB46
Q8VH47

PIR ID S21155
JC1227

Unigene ID Hs.80539
Mm.439726
Rn.38641

KEGG ID hsa:5957
mmu:19674
rno:140936

Swiss-Prot ID RECO_MOUSE
RECO_HUMAN
Q8VH47_RAT
Q53XL0_HUMAN
Q2TB46_MOUSE

IPI ID IPI00222363
IPI00219720
IPI00206326

Homologene ID 2177

RGD ID 620258

MGI ID 97883