Protein Slc24a1

URN urn:agi-llid:9187
Connectivity 16
Name Slc24a1
Description solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
Notes SLC24A1 belongs to a family of potassium-dependent sodium/calcium exchangers. Members of this family have 2 large hydrophilic loops and 2 sets of multiple transmembrane-spanning segments (Schnetkamp, 2004 [PubMed 14770312]).[supplied by OMIM]

Pathway visual phototransduction pathway

GO Molecular Function calcium ion binding
calcium, potassium:sodium antiporter activity
antiporter activity
symporter activity

GO Cellular Component membrane
outer membrane
membrane fraction
integral to membrane
integral to plasma membrane

GO Biological Process response to stimulus
transmembrane transport
transport
visual perception
response to light intensity
ion transport
calcium ion transport

Ariadne Ontology Non-voltage K+ efflux
Na+ influx co-transport
Ca++ export

Group Non-voltage K+ efflux
Na+ influx co-transport
Ca++ export
response to stimulus
transmembrane transport
transport
visual perception
response to light intensity
ion transport
calcium ion transport
calcium ion binding
calcium, potassium:sodium antiporter activity
antiporter activity
symporter activity
membrane
outer membrane
membrane fraction
integral to membrane
integral to plasma membrane

MedScan ID 9187

Hugo ID 10975

Human chromosome position 15q22

LocusLink ID 9187
214111
56814

Alias NCKX
RODX
NCKX1
HsT17412
KIAA0702
sodium/potassium/calcium exchanger 1
retinal rod Na-Ca+K exchanger
retinal rod Na+/Ca+/K+ exchanger
Na(+)/K(+)/Ca(2+)-exchange protein 1
MGC27617
sodium/calcium/potassium exchanger
LOC360437
LOC678758
NCKX I
retinal rod Na/Ca/K exchanger
Slc24a I
Slc24a1
solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
solute carrier family 24 (sodium/potassium/calcium exchanger), member I

Organism Homo sapiens
Mus musculus
Rattus norvegicus

GenBank ID NC_000015
NM_004727
NP_004718
NT_010194
NW_925884
NW_001838218
AC_000058
AC_000147
AC011939
AC027220
CH471082
EAW77739
EAW77740
EAW77741
AB014602
BAA31677
AF026132
AAB97832
AF062921
AAC16732
AF062922
AAC77912
AK300633
BAG62323
AK304006
BAG64922
BC012630
BC029407
BC117263
AAI17264
BC143375
AAI43376
O60721
Q17RM9
NC_000075
NM_144813
NP_659062
NT_039474
NW_001030907
AC_000031
AC140243
CH466522
EDL26073
BC016094
AAH16094
BC044859
Q91WD8
NC_005107
NM_020090
NP_064475
NW_047799
NW_001084873
AC_000076
AF176688
AAD53121
Q9QZM6

OMIM ID 603617

Mouse chromosome position 9

GO ID 0015297
0008273
0015293
0006816
0006811
0009642
0050896
0055085
0006810
0007601
0005887
0005624
0019867
0016021
0016020
0005509

Rat chromosome position 8q24

Swiss-Prot Accession O60721
Q17RM9
Q91WD8
Q9QZM6
Q62932
O43485
O75184

Unigene ID Hs.173092
Mm.156124
Rn.205732

KEGG ID hsa:9187
mmu:214111
rno:56814

Swiss-Prot ID NCKX1_RAT
NCKX1_HUMAN
Q91WD8_MOUSE

Cell Localization Membrane
Plasma membrane

IPI ID IPI00215161
IPI00231152
IPI00231153
IPI00767564
IPI00006195
IPI00216460
IPI00128027
IPI00783599

Homologene ID 3472

RGD ID 620080

MGI ID 2384871