| URN | urn:agi-llid:4038 |
|---|---|
| Total Entities | 0 |
| Connectivity | 58 |
| Name | Lrp4 |
| Description | low density lipoprotein receptor-related protein 4 |
| Notes | This gene encodes a member of the low-density lipoprotein receptor-related protein family. The encoded protein may be a regulator of Wnt signaling. Mutations in this gene are associated with Cenani-Lenz syndrome. [provided by RefSeq, May 2010] |
| Ariadne Ontology | Secreted proteins |
|---|
| GO Molecular Function | receptor tyrosine kinase binding |
|---|---|
| protein homodimerization activity | |
| calcium ion binding |
| GO Cellular Component | membrane |
|---|---|
| integral to membrane | |
| plasma membrane |
| GO Biological Process | negative regulation of Wnt receptor signaling pathway |
|---|---|
| negative regulation of canonical Wnt receptor signaling pathway | |
| Wnt receptor signaling pathway | |
| regulation of protein phosphorylation | |
| cell differentiation | |
| receptor clustering | |
| synaptic growth at neuromuscular junction | |
| negative regulation of ossification | |
| multicellular organismal development | |
| anatomical structure development | |
| embryonic digit morphogenesis | |
| kidney development | |
| hair follicle development | |
| dorsal-ventral pattern formation | |
| proximal-distal pattern formation | |
| embryonic limb morphogenesis | |
| odontogenesis of dentin-containing tooth | |
| endocytosis | |
| protein localization |
| Pathway | acetylcholine signaling pathway via nicotinic acetylcholine receptor |
|---|
| Group | negative regulation of Wnt receptor signaling pathway |
|---|---|
| negative regulation of canonical Wnt receptor signaling pathway | |
| Wnt receptor signaling pathway | |
| regulation of protein phosphorylation | |
| cell differentiation | |
| receptor clustering | |
| synaptic growth at neuromuscular junction | |
| negative regulation of ossification | |
| multicellular organismal development | |
| anatomical structure development | |
| embryonic digit morphogenesis | |
| kidney development | |
| hair follicle development | |
| dorsal-ventral pattern formation | |
| proximal-distal pattern formation | |
| embryonic limb morphogenesis | |
| odontogenesis of dentin-containing tooth | |
| endocytosis | |
| protein localization | |
| receptor tyrosine kinase binding | |
| protein homodimerization activity | |
| calcium ion binding | |
| membrane | |
| integral to membrane | |
| plasma membrane | |
| Secreted proteins |
| MedScan ID | 4038 |
|---|
| Hugo ID | 6696 |
|---|
| Human chromosome position | 11p11.2 |
|---|
| LocusLink ID | 4038 |
|---|---|
| 228357 | |
| 83469 |
| Alias | CLSS |
|---|---|
| LRP-4 | |
| LRP10 | |
| MEGF7 | |
| SOST2 | |
| low-density lipoprotein receptor-related protein 4 | |
| multiple epidermal growth factor-like domains 7 | |
| mdig | |
| D230026E03 | |
| 6430526J12Rik | |
| LDLR dan | |
| Kiaa0816 | |
| low density lipoprotein receptor-related protein 4 | |
| OTTMUSP00000015050 | |
| Lrp4 | |
| low density lipoprotein-related protein IV | |
| low density lipoprotein-related protein 4 | |
| low density lipoprotein receptor-related protein IV | |
| 6430526J12 | |
| LOC277398 |
| Organism | Homo sapiens |
|---|---|
| Mus musculus | |
| Rattus norvegicus |
| OMIM ID | 604270 |
|---|---|
| 614305 | |
| 212780 |
| Unigene ID | Hs.4930 |
|---|---|
| Mm.275149 | |
| Mm.469960 | |
| Rn.21381 |
| KEGG ID | hsa:4038 |
|---|---|
| mmu:228357 | |
| rno:83469 |
| Swiss-Prot Accession | O75096 |
|---|---|
| Q8VI56 | |
| Q76LU2 | |
| Q9QYP1 | |
| B2RN39 | |
| Q4AC85 | |
| Q5KTZ5 | |
| A2AGT4 | |
| Q8BPX5 | |
| Q8CBB3 | |
| Q8CCP5 |
| GO ID | 0005509 |
|---|---|
| 0042803 | |
| 0030971 | |
| 0016055 | |
| 0009953 | |
| 0042733 | |
| 0006897 | |
| 0001942 | |
| 0001822 | |
| 0090090 | |
| 0030279 | |
| 0042475 | |
| 0009954 | |
| 0043113 | |
| 0001932 | |
| 0051124 | |
| 0016021 | |
| 0005886 | |
| 0048856 | |
| 0030154 | |
| 0030326 | |
| 0007275 | |
| 0030178 | |
| 0008104 | |
| 0016020 |
| Swiss-Prot ID | LRP4_HUMAN |
|---|---|
| LRP4_MOUSE |
| Cell Localization | Membrane |
|---|
| IPI ID | IPI00930747 |
|---|---|
| IPI00411145 | |
| IPI00411146 |
| Mouse chromosome position | 2 50.0 cM |
|---|
| Rat chromosome position | 3q24 |
|---|
| Homologene ID | 17964 |
|---|
| MGI ID | 2442252 |
|---|
| RGD ID | 619731 |
|---|