Protein Slc18a3

URN urn:agi-llid:6572
Total Entities 0
Connectivity 142
Name Slc18a3
Description solute carrier family 18 (vesicular acetylcholine), member 3
Notes This gene is a member of the vesicular amine transporter family. The encoded transmembrane protein transports acetylcholine into secretory vesicles for release into the extracellular space. Acetylcholine transport utilizes a proton gradient established by a vacuolar ATPase. This gene is located within the first intron of the choline acetyltransferase gene. [provided by RefSeq, Jul 2008]

Ariadne Ontology Neurotransmitter loading
Other transport proteins
Neurotransmitter uptake
Secreted proteins
Biofluids assayable substances

GO Molecular Function acetylcholine binding
acetylcholine transmembrane transporter activity
monoamine transmembrane transporter activity

GO Cellular Component membrane
clathrin-sculpted acetylcholine transport vesicle membrane
AP-1 adaptor complex
AP-2 adaptor complex
integral to plasma membrane
integral to membrane
plasma membrane
cytoplasmic vesicle
synaptic vesicle
axon terminus
terminal button
neuron projection
axon

GO Biological Process transmembrane transport
synaptic transmission
neurotransmitter secretion
acetylcholine transport
monoamine transport

Pathway acetylcholine signaling pathway via muscarinic acetylcholine receptor
acetylcholine signaling pathway via nicotinic acetylcholine receptor

Group Neurotransmitter loading
Other transport proteins
Neurotransmitter uptake
transmembrane transport
synaptic transmission
neurotransmitter secretion
acetylcholine transport
monoamine transport
acetylcholine binding
acetylcholine transmembrane transporter activity
monoamine transmembrane transporter activity
membrane
clathrin-sculpted acetylcholine transport vesicle membrane
AP-1 adaptor complex
AP-2 adaptor complex
integral to plasma membrane
integral to membrane
plasma membrane
cytoplasmic vesicle
synaptic vesicle
axon terminus
terminal button
neuron projection
axon
Secreted proteins
Biofluids assayable substances

MedScan ID 6572

Hugo ID 10936

Human chromosome position 10q11.2

GenBank ID NC_000010
NM_003055
NP_003046
NG_011797
NC_018921
AC_000142
AC073366
CH471187
EAW93093
U10554
AAB92675
AK313094
BAG35918
BC007765
AAH07765
U09210
AAA20497
Q16572
JF432245
ADZ15462
NC_000080
NM_021712
NP_068358
AC_000036
AC167565
AF019045
AAD09151
CH466573
EDL24839
AK158592
BAE34572
BB450928
BC120498
AAI20499
BC137705
AAI37706
BY240679
O35304
NC_005115
NM_031663
NP_113851
AC_000084
CH474046
EDL88914
U34796
X80395
CAA56604
CB693073
U09211
AAA20498
U09838
AAA50831
Q62666

LocusLink ID 6572
20508
60422

Alias VACHT
vesicular acetylcholine transporter
solute carrier family 18 member 3
solute carrier family 18, member 3
VAT
rVAT
solute carrier family 18 (vesicular monoamine) member 3
solute carrier family 18 member III
solute carrier family 18 (vesicular monoamine), member III
solute carrier family 18 (vesicular acetylcholine), member 3
Solute carrier family 18
Slc18a3
OTTHUMP00000019582
MGC12716
solute carrier family 18 (vesicular acetylcholine), member III
VAT channel

Organism Homo sapiens
Mus musculus
Rattus norvegicus

OMIM ID 600336

Unigene ID Hs.654374
Mm.190503
Rn.9987

KEGG ID hsa:6572
mmu:20508
rno:60422

Swiss-Prot Accession Q16572
Q3TYJ1
O35304
Q62666
B2R7S1
Q64351

GO ID 0042166
0005277
0015870
0007269
0007268
0030121
0030122
0043679
0060201
0005887
0016020
0005886
0008021
0008504
0015844
0055085
0030424
0031410
0043005
0043195
0016021

PIR ID I38658

Swiss-Prot ID VACHT_HUMAN
VACHT_RAT

Cell Localization Membrane
Plasma membrane

IPI ID IPI00017623
IPI00326574

Mouse chromosome position 14 10.5 cM

Rat chromosome position 16p16

Homologene ID 11022

MGI ID 1101061

RGD ID 62072

Primary Cell Localization Plasma membrane