| URN | urn:agi-llid:338457 |
|---|---|
| Connectivity | 3 |
| Name | Tlr9 |
| Description | toll-like receptor 9 |
| Pathway | Toll-like receptor signaling pathway |
|---|
| GO Molecular Function | interleukin-1 receptor binding |
|---|---|
| siRNA binding | |
| unmethylated CpG binding | |
| transmembrane receptor activity |
| GO Cellular Component | plasma membrane |
|---|---|
| cytoplasm | |
| intrinsic to membrane | |
| endosome membrane | |
| basolateral plasma membrane | |
| apical plasma membrane |
| GO Biological Process | defense response to bacterium |
|---|---|
| defense response to virus | |
| pathogen-associated molecular pattern dependent induction by symbiont of host innate immunity | |
| positive regulation of interleukin-12 production | |
| positive regulation of interleukin-18 production | |
| negative regulation of interleukin-8 production | |
| positive regulation of interleukin-6 production | |
| positive regulation of interleukin-8 production | |
| positive regulation of interleukin-10 production | |
| positive regulation of chemokine production | |
| positive regulation of tumor necrosis factor production | |
| positive regulation of interferon-beta production | |
| positive regulation of interferon-alpha biosynthetic process | |
| positive regulation of interferon-gamma biosynthetic process | |
| positive regulation of interferon-beta biosynthetic process | |
| signal transduction | |
| positive regulation of I-kappaB kinase-NF-kappaB cascade | |
| positive regulation of JUN kinase activity | |
| positive regulation of toll-like receptor signaling pathway | |
| negative regulation of toll-like receptor signaling pathway | |
| I-kappaB kinase-NF-kappaB cascade | |
| positive regulation of autophagy | |
| positive regulation of gene-specific transcription from RNA polymerase II promoter | |
| positive regulation of NF-kappaB transcription factor activity | |
| negative regulation of NF-kappaB transcription factor activity | |
| positive regulation of NF-kappaB import into nucleus | |
| microglial cell activation during immune response | |
| I-kappaB phosphorylation | |
| innate immune response | |
| toll-like receptor signaling pathway | |
| positive regulation of nitric-oxide synthase biosynthetic process |
| Group | defense response to bacterium |
|---|---|
| defense response to virus | |
| pathogen-associated molecular pattern dependent induction by symbiont of host innate immunity | |
| positive regulation of interleukin-12 production | |
| positive regulation of interleukin-18 production | |
| negative regulation of interleukin-8 production | |
| positive regulation of interleukin-6 production | |
| positive regulation of interleukin-8 production | |
| positive regulation of interleukin-10 production | |
| positive regulation of chemokine production | |
| positive regulation of tumor necrosis factor production | |
| positive regulation of interferon-beta production | |
| positive regulation of interferon-alpha biosynthetic process | |
| positive regulation of interferon-gamma biosynthetic process | |
| positive regulation of interferon-beta biosynthetic process | |
| signal transduction | |
| positive regulation of I-kappaB kinase-NF-kappaB cascade | |
| positive regulation of JUN kinase activity | |
| positive regulation of toll-like receptor signaling pathway | |
| negative regulation of toll-like receptor signaling pathway | |
| I-kappaB kinase-NF-kappaB cascade | |
| positive regulation of autophagy | |
| positive regulation of gene-specific transcription from RNA polymerase II promoter | |
| positive regulation of NF-kappaB transcription factor activity | |
| negative regulation of NF-kappaB transcription factor activity | |
| positive regulation of NF-kappaB import into nucleus | |
| microglial cell activation during immune response | |
| I-kappaB phosphorylation | |
| innate immune response | |
| toll-like receptor signaling pathway | |
| positive regulation of nitric-oxide synthase biosynthetic process | |
| interleukin-1 receptor binding | |
| siRNA binding | |
| unmethylated CpG binding | |
| transmembrane receptor activity | |
| plasma membrane | |
| cytoplasm | |
| intrinsic to membrane | |
| endosome membrane | |
| basolateral plasma membrane | |
| apical plasma membrane |
| MedScan ID | 338457 |
|---|
| LocusLink ID | 338457 |
|---|
| Alias | toll-like receptor 9 |
|---|
| Organism | Rattus norvegicus |
|---|
| GenBank ID | NW_001084876 |
|---|---|
| NM_198131 | |
| NP_937764 | |
| AC_000076 | |
| CH473954 | |
| EDL77326 | |
| AY191271 | |
| AAO91938 | |
| AY197553 | |
| AAO62342 | |
| AY258139 | |
| AAO93109 | |
| AY859725 | |
| AAW50953 | |
| Q5I2M6 | |
| Q6Y1S0 | |
| Q80VG6 | |
| Q80XA5 |
| GO ID | 0005149 |
|---|---|
| 0035197 | |
| 0045322 | |
| 0007249 | |
| 0007252 | |
| 0042742 | |
| 0051607 | |
| 0002282 | |
| 0032088 | |
| 0032717 | |
| 0034122 | |
| 0052033 | |
| 0043123 | |
| 0043507 | |
| 0042346 | |
| 0051092 | |
| 0010508 | |
| 0032722 | |
| 0010552 | |
| 0045356 | |
| 0045359 | |
| 0032728 | |
| 0045078 | |
| 0032733 | |
| 0032735 | |
| 0032741 | |
| 0032755 | |
| 0032757 | |
| 0051770 | |
| 0034123 | |
| 0032760 | |
| 0002224 | |
| 0016324 | |
| 0016323 | |
| 0005737 | |
| 0010008 | |
| 0005886 | |
| 0031224 | |
| 0004888 | |
| 0045087 | |
| 0007165 |
| Swiss-Prot Accession | Q6Y1S0 |
|---|---|
| Q5I2M6 | |
| Q80VG6 | |
| Q80XA5 |
| Unigene ID | Rn.92495 |
|---|
| KEGG ID | rno:338457 |
|---|
| Swiss-Prot ID | Q6Y1S0_RAT |
|---|
| IPI ID | IPI00382375 |
|---|
| RGD ID | 631352 |
|---|