| URN | urn:agi-llid:23318 |
|---|---|
| Total Entities | 0 |
| Connectivity | 41 |
| Name | Zcchc11 |
| Description | zinc finger, CCHC domain containing 11 |
| Notes | ZCCHC11 is an RNA uridyltransferase (EC 2.7.7.52) that uses UTP to add uridines to the 3-prime end of substrate RNA molecules (Jones et al., 2009 [PubMed 19701194]).[supplied by OMIM, Jan 2011] |
| GO Molecular Function | transferase activity |
|---|---|
| nucleotidyltransferase activity | |
| RNA uridylyltransferase activity | |
| nucleic acid binding | |
| metal ion binding | |
| zinc ion binding |
| GO Cellular Component | nucleolus |
|---|---|
| cytoplasm | |
| nucleus |
| GO Biological Process | pre-miRNA processing |
|---|---|
| cytokine production | |
| stem cell maintenance | |
| positive regulation of interleukin-6 production | |
| regulation of lipopolysaccharide-mediated signaling pathway | |
| interleukin-6-mediated signaling pathway | |
| gene silencing by RNA | |
| negative regulation of NF-kappaB transcription factor activity | |
| histone mRNA catabolic process | |
| miRNA catabolic process | |
| RNA 3'-end processing | |
| miRNA metabolic process |
| Pathway | microRNA pathway |
|---|
| Group | pre-miRNA processing |
|---|---|
| cytokine production | |
| stem cell maintenance | |
| positive regulation of interleukin-6 production | |
| regulation of lipopolysaccharide-mediated signaling pathway | |
| interleukin-6-mediated signaling pathway | |
| gene silencing by RNA | |
| negative regulation of NF-kappaB transcription factor activity | |
| transferase activity | |
| nucleotidyltransferase activity | |
| RNA uridylyltransferase activity | |
| histone mRNA catabolic process | |
| miRNA catabolic process | |
| RNA 3'-end processing | |
| miRNA metabolic process | |
| nucleic acid binding | |
| metal ion binding | |
| zinc ion binding | |
| nucleolus | |
| cytoplasm | |
| nucleus |
| LocusLink ID | 23318 |
|---|---|
| 230594 | |
| 313481 |
| Cell Localization | Nucleus |
|---|---|
| Cytoplasm |
| GO ID | 0050265 |
|---|---|
| 0003676 | |
| 0008270 | |
| 0031123 | |
| 0001816 | |
| 0071044 | |
| 0070102 | |
| 0010587 | |
| 0010586 | |
| 0032088 | |
| 0032755 | |
| 0031054 | |
| 0031664 | |
| 0019827 | |
| 0005737 | |
| 0005730 | |
| 0046872 | |
| 0016779 | |
| 0016740 | |
| 0031047 | |
| 0005634 |
| Alias | TUT4 |
|---|---|
| PAPD3 | |
| terminal uridylyltransferase 4 | |
| TUTase 4 | |
| PAP associated domain containing 3 | |
| zinc finger CCHC domain-containing protein 11 | |
| PPAPD3 | |
| mKIAA0191 | |
| 6030404K05Rik | |
| 9230115F04Rik | |
| RP23-406B13.1 | |
| TUT4 TUTase | |
| PAP associated domain containing III | |
| ZCCHC11 | |
| zinc finger, CCHC domain containing 11 | |
| RIKEN cDNA 9230115F04 gene | |
| zinc finger, CCHC domain containing XI | |
| OTTMUSP00000008601 | |
| 6030404K05 | |
| 9230115F04 | |
| DKFZp779C1943 | |
| OTTHUMP00000009913 | |
| KIAA0191 | |
| LOC230595 | |
| LOC277730 | |
| FLJ42878 |
| Mouse chromosome position | 4 |
|---|
| OMIM ID | 613692 |
|---|
| Rat chromosome position | 5q35 |
|---|
| Hugo ID | 28981 |
|---|
| Human chromosome position | 1p32.3 |
|---|
| Swiss-Prot Accession | Q5TAX3 |
|---|---|
| B2RX14 | |
| Q3V3D5 | |
| Q9EQN6 | |
| A2A8R8 | |
| Q3UYT6 | |
| Q5DU43 | |
| A2RRP0 | |
| B7Z8J5 | |
| D3DQ35 | |
| Q12764 | |
| Q5TAX2 | |
| Q5TAX4 | |
| Q86XZ3 |
| Unigene ID | Hs.655407 |
|---|---|
| Mm.25181 | |
| Mm.446602 | |
| Rn.15558 |
| KEGG ID | hsa:23318 |
|---|---|
| mmu:230594 | |
| rno:313481 |
| Swiss-Prot ID | TUT4_MOUSE |
|---|---|
| TUT4_HUMAN |
| EC Number | 2.7.7.52 |
|---|
| Ensembl ID | ENSG00000134744 |
|---|---|
| ENSP00000257177 | |
| ENST00000257177 | |
| ENSP00000360599 | |
| ENST00000371544 | |
| ENSMUSG00000034610 | |
| ENSMUSP00000044836 | |
| ENSMUST00000043368 | |
| ENSMUSP00000120172 | |
| ENSMUST00000155068 | |
| ENSMUSP00000095538 | |
| ENSMUST00000097925 |
| Homologene ID | 35279 |
|---|
| Organism | Homo sapiens |
|---|---|
| Mus musculus | |
| Rattus norvegicus |
| MGI ID | 2445126 |
|---|
| RGD ID | 1310138 |
|---|
| MedScan ID | 23318 |
|---|